Zobrazeno 1 - 10
of 25
pro vyhledávání: '"G C, Ness"'
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 10, Pp 1878-1887 (1994)
We investigated the relationship between plasma cholestanol (5 alpha-dihydrocholesterol) concentrations and the activity and mRNA levels of cholesterol 7 alpha-hydroxylase, the rate-controlling enzyme for bile acid synthesis, in three female sitoster
Externí odkaz:
https://doaj.org/article/b71bcc03515d4d83944ae3099fa7327a
Publikováno v:
Journal of Lipid Research, Vol 33, Iss 8, Pp 1193-1200 (1992)
We investigated the effects of cholesterol, cholestyramine, and taurocholate feeding on steady state specific activities and mRNA levels of hepatic 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase and cholesterol 7 alpha-hydroxylase in the rat. Interru
Externí odkaz:
https://doaj.org/article/b52a0cc42441478eaa33b876b7381605
Publikováno v:
Journal of Lipid Research, Vol 28, Iss 3, Pp 292-304 (1987)
Methods were developed for determination of human mononuclear leukocyte HMG-CoA reductase protein concentration by a noncompetitive, solid phase, bridged biotin-avidin enzyme immunoassay procedure. Leukocyte microsomal HMG-CoA reductase, first immobi
Externí odkaz:
https://doaj.org/article/9b97b2ee708740238fe873f31a00f7f5
Publikováno v:
Journal of lipid research. 39(1)
The effects of atorvastatin on the expression of the hepatic HMG-CoA reductase and LDL receptor genes were investigated in rats. Like the other statins, atorvastatin increased the rate of degradation and presumably cycling of the hepatic LDL receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c24521373fb27dee9608f2e72addde34
https://pubmed.ncbi.nlm.nih.gov/9469588
https://pubmed.ncbi.nlm.nih.gov/9469588
Publikováno v:
American journal of medical genetics. 68(3)
A limitation to treating Smith-Lemli-Opitz infants by giving dietary cholesterol is their impaired ability to absorb cholesterol due to a deficiency of bile acids. Since intravenously administered lipoprotein cholesterol should not require bile acids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d14e2a0ee003b353e0a9c0896f130f5a
https://pubmed.ncbi.nlm.nih.gov/9024567
https://pubmed.ncbi.nlm.nih.gov/9024567
Publikováno v:
Sub-cellular biochemistry. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d58345448fe3b3649a3dce2902341ca2
https://pubmed.ncbi.nlm.nih.gov/9090303
https://pubmed.ncbi.nlm.nih.gov/9090303
Publikováno v:
The Journal of biological chemistry. 269(46)
The question of whether the effects of insulin and glucagon on hepatic 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity are mediated largely by changes in the phosphorylation state of the enzyme or by changes in the quantity of enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee9d5e7e5d876a2741c2ef98bdea37a7
https://pubmed.ncbi.nlm.nih.gov/7961882
https://pubmed.ncbi.nlm.nih.gov/7961882
Autor:
S, Shefer, G, Salen, J, Bullock, L B, Nguyen, G C, Ness, Z, Vhao, P F, Belamarich, I, Chowdhary, S, Lerner, A K, Batta
Publikováno v:
Hepatology (Baltimore, Md.). 20(1 Pt 1)
We investigated hepatic cholesterol homeostasis in four homozygous sitosterolemic subjects from two unrelated families who showed enhanced absorption, diminished removal and increased tissue and plasma concentrations of sitosterol (24-ethyl cholester
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::10c69138463f13050f9c54fb6ebe25ae
https://pubmed.ncbi.nlm.nih.gov/8020891
https://pubmed.ncbi.nlm.nih.gov/8020891
Autor:
G C, Ness, S J, Nazian
Publikováno v:
Journal of andrology. 13(4)
The developmental expression of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the rate-limiting reaction of mevalonate formation, was investigated in rat testes. Adult testes were found to contain three distinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::514ecd9c281f3d94fb150c0c3dabfe2a
https://pubmed.ncbi.nlm.nih.gov/1399833
https://pubmed.ncbi.nlm.nih.gov/1399833
Publikováno v:
Journal of lipid research. 33(7)
Sitosterolemia is a rare inherited lipid storage disease characterized chemically by the accumulation of plant sterols and 5 alpha-saturated stanols in plasma and tissues. Very low cholesterol synthesis due to a deficiency of HMG-CoA reductase associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d56d5ee59dfa4fbe1ca25cf6df81b789
https://pubmed.ncbi.nlm.nih.gov/1431587
https://pubmed.ncbi.nlm.nih.gov/1431587