Zobrazeno 1 - 5
of 5
pro vyhledávání: '"G C, Grosveld"'
Publikováno v:
Blood. 95:3341-3348
The ETS family of proteins is a large group of transcription factors implicated in many aspects of normal hematopoietic development, as well as oncogenesis. For example, the TEL1/ETV6 (TEL1) gene is required for normal yolk sac angiogenesis, adult bo
Autor:
S C, Raimondi, S A, Shurtleff, J R, Downing, J, Rubnitz, S, Mathew, M, Hancock, C H, Pui, G K, Rivera, G C, Grosveld, F G, Behm
Publikováno v:
Blood. 90(11)
Although abnormalities involving the short arm of chromosome 12 (12p) are one of the most frequently observed rearrangements in childhood acute lymphoblastic leukemia (ALL), little is known about the frequency of different structural abnormalities an
Autor:
Dario A. A. Vignali, Mark Y. Sangster, J. M. Van Deursen, William E. Thierfelder, S. R. Sarawar, R. T. Carson, Peter C. Doherty, G. C. Grosveld, K. Yamamoto, James N. Ihle, Ralph A. Tripp
Publikováno v:
Nature. 382(6587)
Signal transducers and activators of transcription (STATs) are activated by tyrosine phosphorylation in response to cytokines and mediate many of their functional responses. Stat4 was initially cloned as a result of its homology with Stat1 (refs 4, 5
Autor:
R A, Flavell, N K, Moschonas, E, deBoer, G C, Grosveld, M, Busslinger, H H, Dahl, F G, Grosveld
Publikováno v:
Progress in clinical and biological research.
Publikováno v:
Blood. 72(6)
The major consequence of the Philadelphia (Ph) translocation in chronic myeloid leukemia (CML) is the formation of a bcr-abl hybrid oncogene encoding a tumor cell-specific protein P210bcr-abl. In contrast to this, in Ph chromosome-positive acute lymp