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Signaling pathways recruited by the cardiotrophin-like cytokine/cytokine-like factor-1 composite cytokine: specific requirement of the membrane-bound form of ciliary neurotrophic factor receptor alpha component

Autor: E, Lelièvre, H, Plun-Favreau, S, Chevalier, J, Froger, C, Guillet, G C, Elson, J F, Gauchat, H, Gascan

Publikováno v: The Journal of biological chemistry. 276(25)

Ciliary neurotrophic factor (CNTF) is a cytokine supporting the differentiation and survival of a number of neural cell types. Its receptor complex consists of a ligand-binding component, CNTF receptor (CNTFR), associated with two signaling receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3b02eb91f8b34284fb1a5f071cdc128
https://pubmed.ncbi.nlm.nih.gov/11294841

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Cytokine-like factor-1, a novel soluble protein, shares homology with members of the cytokine type I receptor family

Autor: G C, Elson, P, Graber, C, Losberger, S, Herren, D, Gretener, L N, Menoud, T N, Wells, M H, Kosco-Vilbois, J F, Gauchat

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 161(3)

In this report we describe the identification, cloning, and expression pattern of human cytokine-like factor 1 (hCLF-1) and the identification and cloning of its murine homologue. They were identified from expressed sequence tags using amino acid seq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::91ef8e3c0f1faa425d2b837d47728691
https://pubmed.ncbi.nlm.nih.gov/9686600

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