Zobrazeno 1 - 8
of 8
pro vyhledávání: '"G C, Crawley"'
Autor:
M. T. Briggs, G. C. Crawley
Publikováno v:
ChemInform. 26
Autor:
M. P. Edwards, S. J. Foster, J. F. Kingston, R. M. Mcmillan, J.-M. Girodeau, T. G. C. Bird, G. C. Crawley
Publikováno v:
Agents and Actions. 34:110-112
Methoxyalkyl thiazoles are novel 5-lipoxygenase inhibitors which are neither redox agents nor iron chelators and are exemplified by ICI211965 [1-(3-(naphth-2-ylmethoxy)phenyl)-1-(thiazol-2-yl)prop yl methyl ether]. ICI211965 potently inhibits LTC4 sy
Autor:
G C, Crawley, T G, Bird, P, Bruneau, R I, Dowell, P N, Edwards, S J, Foster, J M, Girodeau, R M, McMillan, E R, Walker, D, Waterson
Publikováno v:
Journal of lipid mediators. 6(1-3)
Structure and activity relationships of (methoxyalkyl)thiazole and 4-methoxytetrahydropyran series of 5-lipoxygenase inhibitors are reviewed. One member of the 4-methoxytetrahydropyran series, 6-([fluoro-5-(4-methoxy-3,4,5,6-tetrahydro-2H-pyran-4-yl)
Autor:
G. C. CRAWLEY
Publikováno v:
Chemischer Informationsdienst. 12
Autor:
G. C. Crawley, J. Harley-Mason
Publikováno v:
Chemischer Informationsdienst. Organische Chemie. 2
Publikováno v:
Chemischer Informationsdienst. Organische Chemie. 1
Autor:
John Harley-Mason, G. C. Crawley
Publikováno v:
J. Chem. Soc. D. :685-686
Publikováno v:
Journal of the Chemical Society C: Organic. :1725
On incubation with selected micro-organisms mycophenolic acid (1) has been found to undergo one or more of the following transformations: (a) oxygenation of the 4-methyl group giving an alcohol (5) and an aldehyde (6), (b) oxygenation of the 3′-met