Zobrazeno 1 - 10
of 27
pro vyhledávání: '"G C, Chamness"'
Autor:
S, Oesterreich, S G, Hilsenbeck, D R, Ciocca, D C, Allred, G M, Clark, G C, Chamness, C K, Osborne, S A, Fuqua
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 2(7)
Heat shock protein 27 (hsp27) belongs to the family of heat shock proteins and is thought to be involved in thermotolerance, cell proliferation, drug resistance, and chaperone processes. The aim of this study was to investigate whether hsp27 levels a
Publikováno v:
Cancer. 74(5)
The incidence of estrogen receptor (ER)-positive breast cancer apparently is increasing. It remains unclear whether this increase is due to an improvement in receptor assay sensitivity, a change in patient characteristics, or a change in tumor biolog
Autor:
C K, Osborne, G C, Chamness
Publikováno v:
Breast cancer research and treatment. 32(1)
Autor:
R, Molina, D R, Ciocca, A K, Tandon, D C, Allred, G M, Clark, G C, Chamness, W J, Gullick, W L, McGuire
Publikováno v:
Anticancer research. 12(6B)
Three hundred and one primary breast cancers from patients with tumor infiltrated lymph nodes were analyzed for the presence of HER-2/neu oncoprotein by two procedures: Western blot (WB) and immunohistochemistry (IHC). Overexpression of this protein
Publikováno v:
Cancer. 70
Every month, treatment decisions must be made for more than 6000 patients with breast cancer without axillary node involvement in the United States. Approximately 70% of these patients will survive more than 10 years after surgery and/or radiation tr
Publikováno v:
Journal of the National Cancer Institute. Monographs. (11)
Treatment decisions must be made on 9000 axillary node-negative breast cancer patients each month in the United States. Which of these patients will benefit from adjuvant therapy is a major question. Valid methods are needed to distinguish those pati
Publikováno v:
Cancer surveys. 14
We have used the screening techniques of CMC and SSCP of selected PCR fragments, and also gel retardation assays, to discover a number of ER variants in clinical breast cancer tissues. We have found base pair insertions, transitions, and deletions, a
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 5(11)
We have used the screening techniques of chemical mismatch cleavage, single stranded conformational polymorphism, and gel retardation to discover a number of estrogen receptor RNA variants in clinical breast cancer tissues. We have found basepair ins
Autor:
S A, Fuqua, S D, Fitzgerald, G C, Chamness, A K, Tandon, D P, McDonnell, Z, Nawaz, B W, O'Malley, W L, McGuire
Publikováno v:
Cancer research. 51(1)
Since progesterone receptor (PgR) is normally induced by estrogen, breast cancer lacking estrogen receptor (ER) would also be expected to lack PgR. However, a small percentage of breast cancers are ER- yet PgR+. These tumors might possess an ER which
Publikováno v:
Cancer research. 50(13)
DNA methylation is known to be involved in eukaryotic gene control; it may thus exert effects during development and tumorigenesis. We have examined the methylation status of the estrogen receptor (ER) gene in different human tissues. The ER gene was