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Effect of polymeric black tea polyphenols on benzo(a)pyrene [B(a)P]-induced cytochrome P4501A1 and 1A2 in mice

Autor: G. B. Maru, R. Krishnan, R. Raghunathan

Publikováno v: Xenobiotica. 35:671-682

The chemopreventive activity of green tea polyphenols (GTPs) is, in part, due to modulation of cytochrome P450s (CYPs). To investigate the enzyme modulatory properties of major black tea polyphenols, the effect of decaffeinated black tea extract (DBT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40889a31befe3eedf393bdd10d99e6b9
https://doi.org/10.1080/00498250500202155

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The Distribution of Total Particulate Matter (TPM) And Nicotine Between Mainstream and Sidestream Smoke in Bidis and Cigarettes

Autor: G. B. Maru, S. S. Pakhale, S. S. Dolas

Publikováno v: Analytical Letters. 30:383-394

The mainstream (MS) and sidestream (SS) smoke of three types of popular Indian cigarettes, a brand of low tar Indian cigarettes, a brand of US cigarettes and two brands of popular Indian bidis were analysed for carcinogenic total particulate matter (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::588e04a4b06cb7669b4953015bb82ff2
https://doi.org/10.1080/00032719708002810

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Effects of turmeric on the activities of benzo(a)pyrene-induced cytochrome P-450 isozymes

Autor: R, Thapliyal, S S, Deshpande, G B, Maru

Publikováno v: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 20(1)

Turmeric and/or its main coloring component, curcumin (diferuloylmethane), have been shown to inhibit benzo(a)pyrene [B(a)P]-induced forestomach papillomas in mice. However, the mechanisms of turmeric-mediated chemoprevention are not well understood.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8fb14630cd07faa8c209a7de55dac2da
https://pubmed.ncbi.nlm.nih.gov/11215708

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Subchronic oral hepatotoxicity of turmeric in mice--histopathological and ultrastructural studies

Autor: S V, Kandarkar, S S, Sawant, A D, Ingle, S S, Deshpande, G B, Maru

Publikováno v: Indian journal of experimental biology. 36(7)

Dietary administration of the whole spice turmeric (0.2%, 1.0%, 5.0%) or ethanolic turmeric extract (ETE, 0.05%, 0.25%) for 14 days, at doses reported to be cancer preventive in model systems, were found to be hepatotoxic in mice. Histopathological e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4df85972daa1bc02b552dd6df3fa83ca
https://pubmed.ncbi.nlm.nih.gov/9782784

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Dna Damage as a Marker of Exposure to Carcinogens

Autor: S. V. Bhide, G. B. Maru

Publikováno v: Journal of Toxicology: Toxin Reviews. 8:177-194

The biochemical and molecular basis of cancer continues to be an expanding area of research at least in part due to concerns about increasing human health risks caused by exposure to toxic chemicals of both industrial and natural origin. Recently bio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::595a82255255b2245f1f397ea9c4bef2
https://doi.org/10.3109/15569548909059749

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Preliminary observations on interaction of 14C-metronidazole with macromolecules in vivo and in vitro

Autor: M, Chacko, G B, Maru, S V, Bhide

Publikováno v: Indian journal of physiology and pharmacology. 30(3)

Preliminary studies on the in vivo and in vitro interactions of 14C-metronidazole with macromolecules showed that the agent or its metabolite(s) can interact with nucleic acids and proteins in vivo. In vitro studies suggest that in absence of DNA syn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bb8d4d55d684576e0fb64ffc68d49a5f
https://pubmed.ncbi.nlm.nih.gov/3557608

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