Zobrazeno 1 - 10
of 39
pro vyhledávání: '"G B, Landwehrmeyer"'
Autor:
Jacob Lahr, Lora Minkova, Sarah J. Tabrizi, Julie C. Stout, Stefan Klöppel, Elisa Scheller, the TrackOn-HD Investigators, A. Coleman, J. Decolongon, M. Fan, T. Koren, C. Jauffret, D. Justo, S. Lehericy, K. Nigaud, R. Valabrègue, A. Schoonderbeek, E. P. ‘t Hart, H. Crawford, S. Gregory, D. Hensman Moss, E. Johnson, J. Read, G. Owen, M. Papoutsi, C. Berna, A. Razi, G. Rees, R. I. Scahill, D. Craufurd, R. Reilmann, N. Weber, J. Stout, I. Labuschagne, M. Orth, G. B. Landwehrmeyer, D. Langbehn, H. Johnson, J. Long, J. Mills
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Huntington’s disease (HD) is a genetically caused neurodegenerative disorder characterized by heterogeneous motor, psychiatric, and cognitive symptoms. Although motor symptoms may be the most prominent presentation, cognitive symptoms such as memor
Externí odkaz:
https://doaj.org/article/c4ae59d737bd4473a864c93be1985ab9
Publikováno v:
Der Nervenarzt. 91(4)
In Germany at least 8000 and probably up to ca. 14,000 people currently suffer from clinically manifest Huntington's disease (HD). In addition, an estimated 24,000 Germans carry the HD mutation in the huntingtin (HTT) gene and will develop HD during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48ee641e35e1255ced861ceaaf6a6aac
https://pubmed.ncbi.nlm.nih.gov/32179957
https://pubmed.ncbi.nlm.nih.gov/32179957
Autor:
Frank Birklein, Elena K. Krumova, Christian Maihöfner, Volker Huge, D.-R. Treede, Thomas R. Tölle, Roman Rolke, Nurcan Üçeyler, V. Tronnier, R. Baron, Walter Magerl, Claudia Sommer, Christoph Maier, Andrea Scherens, Janne Gierthmühlen, Gunnar Wasner, Andreas Binder, Michael Valet, Niels Birbaumer, Helmut Richter, Herta Flor, Christian Geber, G. B. Landwehrmeyer, A. Schwarz
Publikováno v:
Pain. 150:439-450
Neuropathic pain is accompanied by both positive and negative sensory signs. To explore the spectrum of sensory abnormalities, 1236 patients with a clinical diagnosis of neuropathic pain were assessed by quantitative sensory testing (QST) following t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484f5a75e45f17900f8c60c232902b5b
https://doi.org/10.1016/j.pain.2010.05.002
https://doi.org/10.1016/j.pain.2010.05.002
Autor:
Roman Rolke, Michael Valet, Christoph Maier, Niels Birbaumer, Till Sprenger, Christian Maihöfner, B. Wasserka, I. C. Bötefür, Ralf Baron, G. B. Landwehrmeyer, Frank Birklein, Herta Flor, C. Schaub, C. Rolko, Andreas Binder, Volker Huge, Andrea Scherens, Antje Beyer, Walter Magerl, Rolf-Detlef Treede, Thomas R. Tölle, R. Klug, S. Braune
Publikováno v:
Pain. 123:231-243
The nationwide multicenter trials of the German Research Network on Neuropathic Pain (DFNS) aim to characterize the somatosensory phenotype of patients with neuropathic pain. For this purpose, we have implemented a standardized quantitative sensory t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3dee4010200b063c1f3f2467f3ca28
https://doi.org/10.1016/j.pain.2006.01.041
https://doi.org/10.1016/j.pain.2006.01.041
Autor:
J. M. Vetter, Thomas J. Feuerstein, G. B. Landwehrmeyer, Rolf Jackisch, J. Heinemeyer, T. Jehle, P. Franz, P. F. Behrens
Publikováno v:
Journal of Neurochemistry. 85:1054-1063
In Huntington's disease (HD), neuronal loss is most prominent in the striatum leading to emotional, cognitive and progressive motor dysfunction. The R6/2 mice, transgenic for exon 1 of the HD gene, develop a neurological phenotype with similarities t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a12491ca27fe1d255e87b7c7aca745d3
https://doi.org/10.1046/j.1471-4159.2003.01704.x
https://doi.org/10.1046/j.1471-4159.2003.01704.x
Autor:
Thomas F. Meyer, Birgit Schwalenstöcker, M. Ebstein, Bing-gen Zhu, G. B. Landwehrmeyer, Christoph Münch, Stefan Stamm, U. Seefried, Albert C. Ludolph
Publikováno v:
Journal of Neurochemistry. 82:594-603
Glutamate-mediated neurotoxicity and a reduced expression of the excitatory amino acid transporter 2 (EAAT2) have been described in the pathogenesis of several acute and chronic neurological conditions. EAAT2 is the major carrier of glutamate in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::147793255adf2f3e3d55f512689f69ec
https://doi.org/10.1046/j.1471-4159.2002.01012.x
https://doi.org/10.1046/j.1471-4159.2002.01012.x
Autor:
M. Darstein, Carl Hermann Lücking, C Albrecht, P. A. Löschmann, G B Landwehrmeyer, C Deransart, Thomas J. Feuerstein, C De Groote
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 363:414-421
Using the rat model of Parkinson's disease described by Ungerstedt the release of [3H]acetylcholine ([3H]ACh) in the caudatoputamen was investigated to assess possible long-term effects of unilateral dopaminergic denervation on the modulation of chol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c364b7dc5b94780df7e1224be192050a
https://doi.org/10.1007/s002100000373
https://doi.org/10.1007/s002100000373
Autor:
Anne B. Young, G B Landwehrmeyer, Küppenbender Kd, David G. Standaert, T. J. Feuerstein, J. B. Penney
Publikováno v:
The Journal of Comparative Neurology. 419:407-421
N-methyl-D-aspartate (NMDA) receptors are composed of subunits from two families: NR1 and NR2. We used a dual-label in situ hybridization technique to assess the levels of NR1 and NR2A-D messenger ribonucleic acid (mRNA) expressed in projection neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99c501250cea6abdcfd87b704c23ad74
https://doi.org/10.1002/(sici)1096-9861(20000417)419:4<407::aid-cne1>3.0.co
https://doi.org/10.1002/(sici)1096-9861(20000417)419:4<407::aid-cne1>3.0.co
Publikováno v:
The Journal of Comparative Neurology. 415:204-217
Alternative splicing of the mRNA encoding the N-methyl-D-aspartate (NMDA) receptor subunit NR1 changes the structural, physiologic, and pharmacologic properties of the resultant NMDA receptors. We used dual label immunocytochemistry and confocal micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba104d937f17d544ddca343f8e6f6314
https://doi.org/10.1002/(sici)1096-9861(19991213)415:2<204::aid-cne5>3.0.co
https://doi.org/10.1002/(sici)1096-9861(19991213)415:2<204::aid-cne5>3.0.co
Autor:
J. B. Penney, Gonul Velicelebi, Christoph M. Kosinski, T J Counihan, Clemens R. Scherzer, David G. Standaert, Lorrie P. Daggett, G B Landwehrmeyer, Anne B. Young, J A Kerner
Publikováno v:
The Journal of Comparative Neurology. 390:63-74
N-methyl-D-aspartate receptors (NRs) play an important role in basal ganglia function. By using in situ hybridization with ribonucleotide probes, we investigated the regional and cellular distribution of NR subunit mRNA expression in the human basal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e86330d0e83f519225f17dd006ea5d7f
https://doi.org/10.1002/(sici)1096-9861(19980105)390:1<63::aid-cne6>3.0.co
https://doi.org/10.1002/(sici)1096-9861(19980105)390:1<63::aid-cne6>3.0.co