Prostate cancer and Hedgehog signalling pathway

Autor: J. Cassinello Espinosa, G. Aparicio Gallego, R. García Campelo, S. Díaz Prado, L. M. Antón Aparicio, M. Valladares Ayerbes, M. Reboredo López

Publikováno v: ResearcherID
RUC. Repositorio da Universidade da Coruña
instname

[Abstract] The Hedgehog (Hh) family of intercellular signalling proteins have come to be recognised as key mediators in many fundamental processes in embryonic development. Their activities are central to the growth, patterning and morphogenesis of m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47ecd9415115b0945b470f54ba46d37
https://doi.org/10.1007/s12094-007-0080-x

Multiple biomarker tissue arrays: A computational approach to identifying protein-protein interactions in the EGFR/ERK signalling pathway

Autor: G. Aparicio Gallego, L. Miguel Antón Aparicio, V. Medina Villaamil, I. Santamarina Caínzos, Manuel Valladares-Ayerbes

Publikováno v: RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
Journal of Molecular Signaling; Vol 7 (2012); Art. 14
RUC. Repositorio da Universidade da Coruña
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Journal of Molecular Signaling

[Abstract] Background. Many studies have demonstrated genetic and environmental factors that lead to renal cell carcinoma (RCC) and that occur during a protracted period of tumourigenesis. It appears suitable to identify and characterise potential mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a31a79567795997ec212efb46d1b74d6
http://hdl.handle.net/20.500.11940/7818

Tissue array analysis for the differentiation of gliosis from gliomas

Autor: S. Díaz Prado, M. Valladares Ayerbes, L. M. Antón Aparicio, A. Álvarez García, L. A. Rivas López, V. Medina Villaamil, I. Santamarina Caínzos, G. Aparicio Gallego

Publikováno v: RUC. Repositorio da Universidade da Coruña
instname
RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)

[Abstract] The aim of this study was to provide a methodology to make a clear distinction between malignant tumors and morphologically similar benign processes, by examining the expression of EGFR, VEGF, HIF1-α, survivin, Bcl-2 and p53 proteins. Fou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e484d169b4621c071848191b993dc4
https://hdl.handle.net/2183/14681

MicroRNAs as emerging biomarkers for micrometastasis detection in genitourinary tumors

Autor: R. García Campelo, Margarita Reboredo, S. Antolín Novoa, G. Aparicio Gallego, M. Valladares Ayerbes, D. Dopico Vázquez, L. M. Antón Aparicio, V. Medina Villaamil, M. Quindós Varela, I. Santamarina Caínzos

Publikováno v: RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)

52 Background: MicroRNAs regulate numerous aspects of normal and pathological cellular processes, including cancer. Detection of circulating tumor cells (CTC) may provide diagnostic and prognostic information in genitourinary (GU) tumors. miRNAs may

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02fe5c10aae4bb84bbff5a81665c112d
http://hdl.handle.net/20.500.11940/3001

Cyclooxygenase-2 (COX-2): a molecular target in prostate cancer

Autor: G. Aparicio Gallego, S. Díaz Prado, J. Cassinello Espinosa, L. M. Antón Aparicio, P. Jiménez Fonseca, R. García Campelo

Publikováno v: RUC. Repositorio da Universidade da Coruña
instname

[Abstract] Epidemiological studies provided the first evidence that COX may be involved in the pathogenesis of cancer. In the process of carcinogenesis and in the route of intracellular signalling during carcinogenesis, COX-2 expression may be a univ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed72f6fd30923b08a2c95eb1cce6b76
https://pubmed.ncbi.nlm.nih.gov/18055324