Zobrazeno 1 - 4
of 4
pro vyhledávání: '"G Alan, Nickols"'
Autor:
James W. Malecha, Christina N. Steininger, Melanie L. Williams, Kristen E. Shannon, Thomas Rogers, Bryan H. Landis, Tiffany Duffin, Srinivasan Nagarajan, Pegg Jodi Ann, Hwang-Fun Lu, Rico Joseph G, Maureen A. Nickols, Jun Zhu, Sandra K. Freeman, V. Wayne Engleman, David W. Griggs, G. Alan Nickols, Jeffery L. Keene, Devadas Balekudru, Debra M. Meyer, Marisa M. Westlin, Larry Miller, Laura D. Marrufo, Nawasa F. Green, Melissa K. Lantz, Mark A. Russell, Peter G. Ruminski, Mary Beth Finn, H. Peter Kleine, Joe T. Collins
Publikováno v:
Bioorganic & Medicinal Chemistry. 15:3783-3800
The integrin αvβ3, vitronectin receptor, is expressed in a number of cell types and has been shown to mediate adhesion of osteoclasts to bone matrix, vascular smooth muscle cell migration, and angiogenesis. We recently disclosed the discovery of a
Autor:
Srinivasan Nagarajan, Ish K. Libertyville Khanna, Tiffany Duffin, Alan F. Gasiecki, Jeffery L. Keene, Mihir D. Parikh, Michael Clare, Marisa M. Westlin, Maureen A. Nickols, Christina A. Steininger, Melanie L. Williams, Hwang-Fun Lu, Thomas Rogers, Jon A. Klover, Mary Beth Finn, V. Wayne Engleman, Sandra K. Freeman, William F. Westlin, Barbara B. Chen, G. Alan Nickols, Kristen E. Shannon, Mark A. Russell, Bipinchandra N. Desai
Publikováno v:
Bioorganic & Medicinal Chemistry. 15:3390-3412
The integrin alpha(v)beta(3) is expressed in a number of cell types and is thought to play a major role in several pathological conditions. Various small molecules that inhibit the integrin have been shown to suppress tumor growth and retinal angioge
Autor:
Srinivasan Nagarajan, G. Alan Nickols, Jon A. Klover, David W. Griggs, Sandra K. Freeman, V. Wayne Engleman, Jane M. Meyer, Julie M. Miyashiro
Publikováno v:
Chemical Biology Drug Design. 67:177-181
A peptidomimetic inhibitor of the integrin alpha(v)beta(3) has been substantially modified to produce several new nonpeptidic antagonists. These inhibitors are simpler to synthesize and belong to new classes of scaffolds. Some of the compounds served
Autor:
Srinivasan R, Nagarajan, Balekudru, Devadas, James W, Malecha, Hwang-Fun, Lu, Peter G, Ruminski, Joseph G, Rico, Thomas E, Rogers, Laura D, Marrufo, Joe T, Collins, H Peter, Kleine, Melissa K, Lantz, Jun, Zhu, Nawasa F, Green, Mark A, Russell, Bryan H, Landis, Lawrence M, Miller, Debra M, Meyer, Tiffany D, Duffin, V Wayne, Engleman, Mary B, Finn, Sandra K, Freeman, David W, Griggs, Melanie L, Williams, Maureen A, Nickols, Jodi A, Pegg, Kristen E, Shannon, Christina, Steininger, Marisa M, Westlin, G Alan, Nickols, Jeffery L, Keene
Publikováno v:
Bioorganicmedicinal chemistry. 15(11)
The integrin alpha(v)beta(3), vitronectin receptor, is expressed in a number of cell types and has been shown to mediate adhesion of osteoclasts to bone matrix, vascular smooth muscle cell migration, and angiogenesis. We recently disclosed the discov