Zobrazeno 1 - 10 of 71 pro vyhledávání: '"G A Silverman"'
1
Systemic lupus erythematosus aggravates atherosclerosis by promoting IgG deposition and inflammatory cell imbalance
Autor: T Liu, N Shi, S Zhang, G J Silverman, X-W Duan, H Niu
Publikováno v: Lupus
Background Systemic lupus erythematosus (SLE) patients experience a premature and more severe presentation of coronary artery disease. The underlying mechanisms of accelerated coronary artery disease in SLE patients remain to be elucidated. Methods B
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c0a04d10caebd1a3da8c31b6cba02e
https://doi.org/10.1177/0961203320904779
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2
Application of Enzyme-Linked Immunosorbent Assay for Detection of Staphylococcal Enterotoxins in Food
Autor: G. J. Silverman, J. K. S. Kuo
Publikováno v: Journal of food protection. 43(5)
The enzyme-linked immunospecific assay (ELISA) is equally as sensitive as the radioimmunoassay (RIA) for detecting staphylococcal enterotoxins (SE). The substitution of an enzyme in ELISA for I-125 in RIA results in a more stable reagent and enables
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::840bc02cf07fe9de8ff92ce3b9a38fd0
https://pubmed.ncbi.nlm.nih.gov/30822871
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3
VH3 family antibodies bind domain D of staphylococcal protein A
Autor: P W Roben, A N Salem, G J Silverman
Publikováno v: The Journal of Immunology. 154:6437-6445
Staphylococcal protein A (SpA) is a 45-kDa bacterial membrane protein that can interact with either Fc gamma, a constant region portion of IgG, or with the Fab portion that also mediates conventional Ag binding. In recent reports, SpA has been shown
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e6987606b5c297ee37008f088a048c8
https://doi.org/10.4049/jimmunol.154.12.6437
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4
Molecular selection of human antibodies with an unconventional bacterial B cell antigen
Autor: M Sasano, D R Burton, G J Silverman
Publikováno v: The Journal of Immunology. 151:5822-5839
Unconventional Ag for B cells that are comparable to known superantigens for T lymphocytes have not been well characterized. However, the bacterial membrane protein, Staphylococcal protein A (SpA), has sites that interact with the Fab of many IgM, Ig
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc02fb831945ca631fc98cb1c328b788
https://doi.org/10.4049/jimmunol.151.10.5822
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5
Age-associated changes in binding of human B lymphocytes to a VH3-restricted unconventional bacterial antigen
Autor: G J Silverman, M Sasano, S B Wormsley
Publikováno v: The Journal of Immunology. 151:5840-5855
We have recently demonstrated that there is a site on Staphylococcal protein A (SpA) that interacts with B cell Ig receptors in a manner comparable with known T cell superantigens, because this binding specificity is restricted to Fab with VH3 H chai
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82466cca499ada1c0aadf84953622c0e
https://doi.org/10.4049/jimmunol.151.10.5840
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6
Genetic transfer and expression of reconstructed yeast artificial chromosomes containing normal and translocated BCL2 proto-oncogenes
Autor: G A Silverman, E Yang, J H Proffitt, M Zutter, S J Korsmeyer
Publikováno v: Molecular and Cellular Biology. 13:5469-5478
The goal of this study was to determine whether it will be feasible to study the expression of a large, human gene, such as the BCL2 proto-oncogene, by DNA transfection. The BCL2 proto-oncogene is 230 kb in size and is deregulated in tumor cells by t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::705c54cf4ac57c67f1b9f1f512ac1072
https://doi.org/10.1128/mcb.13.9.5469
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9
Human IgA and IgG F(ab')2 that bind to staphylococcal protein A belong to the VHIII subgroup
Autor: E H Sasso, G J Silverman, M Mannik
Publikováno v: The Journal of Immunology. 147:1877-1883
Staphylococcal protein A (SPA) is a bacterial membrane protein that possesses, in addition to its Fc gamma-binding activity, a distinct specificity for the Fab region of some IgM, IgA, IgG, and IgE. The Fab site that binds to SPA has been localized t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a80d02794e64fedcbb34937cda3ed300
https://doi.org/10.4049/jimmunol.147.6.1877
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10
Intraclonal diversity in the VH genes expressed by CD5- chronic lymphocytic leukemia-producing pathologic IgM rheumatoid factor
Autor: J Roudier, G J Silverman, P P Chen, D A Carson, T J Kipps
Publikováno v: The Journal of Immunology. 144:1526-1530
The leukemic cells from 95% of patients with B cell chronic lymphocytic leukemia (CLL) coexpress B cell differentiation antigens and the pan-T lymphocyte surface antigen CD5 (Leu 1). As such, CLL generally may be considered a malignancy of the CD5 B
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de5afa65da95d82b0d8969a5f7e499a3
https://doi.org/10.4049/jimmunol.144.4.1526
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