Zobrazeno 1 - 10
of 80
pro vyhledávání: '"G A Limb"'
Publikováno v:
Organoids, Vol 3, Iss 3, Pp 148-164 (2024)
In zebrafish and various mammalian species, HB-EGF has been shown to promote Müller glia proliferation and activation of repair mechanisms that have not been fully investigated in human retina. In the current study, 70- to 90-day-old human retinal o
Externí odkaz:
https://doaj.org/article/3a7e7adf34094f029439ca6e01e48c65
Autor:
William D. B. Lamb, Karen Eastlake, Joshua Luis, Najam A. Sharif, Peng T. Khaw, G. Astrid Limb
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2024)
IntroductionAs with any other radial glia in the central nervous system, Müller glia derive from the same neuroepithelial precursors, perform similar functions, and exhibit neurogenic properties as radial glia in the brain. Müller glial cells retai
Externí odkaz:
https://doaj.org/article/9ecf20fce74d49e7adbb0f170f740a47
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Müller glia play very important and diverse roles in retinal homeostasis and disease. Although much is known of the physiological and morphological properties of mammalian Müller glia, there is still the need to further understand the prof
Externí odkaz:
https://doaj.org/article/6507aa18b2f64bfb83eea7bc1e220b0d
Publikováno v:
Mathematical Biosciences and Engineering, Vol 17, Iss 3, Pp 2741-2759 (2020)
Chronic eye diseases are the main cause of vision loss among adults. Among these, retinal degenerative diseases affect millions of people globally, causing permanent loss of cells and organ dysfunction. Despite recent progress in developing stem cell
Externí odkaz:
https://doaj.org/article/a754839d8d2d48abbb0972f8ddbd88c5
Autor:
Karen Eastlake, Weixin Wang, Hari Jayaram, Celia Murray‐Dunning, Amanda J. F. Carr, Conor M. Ramsden, Anthony Vugler, Katrina Gore, Nadine Clemo, Mark Stewart, Pete Coffey, Peng T. Khaw, G. Astrid Limb
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 8, Pp 775-784 (2019)
Abstract Glaucoma is one of the leading causes of blindness, and there is an ongoing need for new therapies. Recent studies indicate that cell transplantation using Müller glia may be beneficial, but there is a need for novel sources of cells to pro
Externí odkaz:
https://doaj.org/article/3318628640d742c6b2a42b2b510967aa
Publikováno v:
Current Eye Research
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Purpose A major challenge in glaucoma research is the lack of reproducible animal models of RGC and optic nerve damage, the characteristic features of this condition. We therefore examined the glaucomatous responses of two different rat strains, the
Autor:
Dalia Abdulhussein, Abu Abraham, Vivek Agrahari, Mourad Amrane, Ananta Ayyagari, Franz Buchholzer, James E. Chastain, Chiungkuang Chen, Andy K. Cheng, Audrey Chia, M. Francesca Cordeiro, Philippe Daull, Mitchell A. deLong, Li Lian Foo, Pooja Gudibanda, Martina C. Herwig-Carl, Alex A. Huang, Shahid Husain, Chinenye Idigo, Schuichi Koizumi, Sade Kosoko-Lasaki, Megan S. Kuhn, Aishwarya Kundu, William D.B. Lamb, Alex Leung, Yu Meng Li, G. Astrid Limb, Karin U. Loeffler, Phil Luthert, Leah Makley, Haider Manzar, Fiona S. McDonnell, Marshalyn G. McKoy, Hideki Miyake, Samarendra Mohanty, Sreenivasu Mudumba, Fatima Muili, Darryl Narcisse, Wei Yan Ng, Kalu K. Ngele, Ya Fatou Njie-Mbye, Sunny E. Ohia, Odochi Ohia-Nwoko, Shin-ichi Ohnuma, Anthonia Okolie, Catherine A. Opere, Leonard Pinchuk, Akash Raola, Omar Sadruddin, Najam A. Sharif, Keiichi Shibagaki, Youichi Shinozaki, Onkar N. Singh, W. Daniel Stamer, Allison Stradiotto, Jill Sturdivant, Masanao Toshimori, Sam Yacoub, Dariush Yalzadeh, Timothy E. Yap, Benjamin R. Yerxa, Gulab Zode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dce76a66523fb39f5bc0283382973d5
https://doi.org/10.1016/b978-0-12-819291-7.00048-4
https://doi.org/10.1016/b978-0-12-819291-7.00048-4
Publikováno v:
Cells, Vol 1, Iss 4, Pp 851-873 (2012)
Retinal degenerative diseases constitute a major cause of irreversible blindness in the world. Stem cell-based therapies offer hope for these patients at risk of or suffering from blindness due to the deterioration of the neural retina. Various sourc
Externí odkaz:
https://doaj.org/article/c04092f87df84408acb04c2d8950826e
Autor:
Peter J. Coffey, Conor M. Ramsden, Weixin Wang, Nadine Clemo, Hari Jayaram, Peng T. Khaw, Amanda J. F. Carr, Katrina Gore, G. Astrid Limb, Anthony Vugler, Karen Eastlake, Mark Stewart, Celia Murray-Dunning
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 8, Pp 775-784 (2019)
Stem Cells Translational Medicine
Stem Cells Translational Medicine
Glaucoma is one of the leading causes of blindness, and there is an ongoing need for new therapies. Recent studies indicate that cell transplantation using Müller glia may be beneficial, but there is a need for novel sources of cells to provide ther