Zobrazeno 1 - 8
of 8
pro vyhledávání: '"G A Arreaza"'
Autor:
William W. Cruikshank, Wei Chen, Konstantin V. Salojin, Craig Meagher, Qing Sheng Mi, Noah Horst, Josh Beilke, G A Arreaza, Terry L. Delovitch
Publikováno v:
Diabetes
OBJECTIVE The progressive infiltration of pancreatic islets by lymphocytes is mandatory for development of autoimmune type 1 diabetes. This inflammatory process is mediated by several mediators that are potential therapeutic targets to arrest develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5189609b404eafa2e265a8b4d2b14d7f
https://doi.org/10.2337/db09-0131
https://doi.org/10.2337/db09-0131
Publikováno v:
Gene Therapy. 7:1840-1846
We have previously shown that systemic injection of multiple low doses of recombinant murine interleukin-4 (mIL-4) can prevent type 1 diabetes (T1D) in nonobese diabetic (NOD) mice by activating regulatory T helper (Th) 2 cells in vivo. Here, we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc369ebf004ddc249ce3f4eb2f79f7ef
https://doi.org/10.1038/sj.gt.3301309
https://doi.org/10.1038/sj.gt.3301309
Publikováno v:
Advances in experimental medicine and biology. 520
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7b8df9cb59572bfd4b40f1c39f323d3
https://pubmed.ncbi.nlm.nih.gov/12613577
https://pubmed.ncbi.nlm.nih.gov/12613577
Autor:
M J, Cameron, G A, Arreaza, P, Zucker, S W, Chensue, R M, Strieter, S, Chakrabarti, T L, Delovitch
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(10)
Beginning at the time of insulitis, nonobese diabetic (NOD) mice demonstrate a thymocyte and peripheral T cell proliferative hyporesponsiveness induced by TCR cross-linking, which is associated with reduced IL-2 and IL-4 secretion. We previously repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41b1bc1e06a93db05013c0e9a597c290
https://pubmed.ncbi.nlm.nih.gov/9366391
https://pubmed.ncbi.nlm.nih.gov/9366391
Autor:
Atsuo Ochi, B. M. Gill, Jian Zhang, Mark J. Cameron, G A Arreaza, Terry L. Delovitch, Konstantin V. Salojin
Publikováno v:
The Journal of Experimental Medicine
Nonobese diabetic (NOD) mouse thymocytes are hyporesponsive to T cell antigen receptor (TCR)-mediated stimulation of proliferation, and this T cell hyporesponsiveness may be causal to the onset of autoimmune diabetes in NOD mice. We previously showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c659fecfc2bc2bf632802c6864b34d0e
https://pubmed.ncbi.nlm.nih.gov/9294143
https://pubmed.ncbi.nlm.nih.gov/9294143
Publikováno v:
Critical reviews in immunology. 17(5-6)
T cells from NOD mice display an age-dependent, TCR-inducible proliferative hyporesponsiveness that may be causal to IDDM. Exogenous IL-4 completely restores this hyporesponsiveness in vitro and prevents IDDM in vivo when administered to NOD mice. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb75ad7a4bb2be0da8c310fa4f998238
https://pubmed.ncbi.nlm.nih.gov/9419441
https://pubmed.ncbi.nlm.nih.gov/9419441
Publikováno v:
G.E.N. 31(4)
The authors used Toluidine Blue to stain gastric lesions in nine patients. Six cases were found with adenocarcinoma that stained an intense blue that was limited to the extension of the malignancy itself. The other three cases did not stain and their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1704c2b57d8d181747a2f9f9e9ffd6ff
https://pubmed.ncbi.nlm.nih.gov/97135
https://pubmed.ncbi.nlm.nih.gov/97135