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pro vyhledávání: '"G A Arreaza"'
Autor:
William W. Cruikshank, Wei Chen, Konstantin V. Salojin, Craig Meagher, Qing Sheng Mi, Noah Horst, Josh Beilke, G A Arreaza, Terry L. Delovitch
Publikováno v:
Diabetes
OBJECTIVE The progressive infiltration of pancreatic islets by lymphocytes is mandatory for development of autoimmune type 1 diabetes. This inflammatory process is mediated by several mediators that are potential therapeutic targets to arrest develop
Publikováno v:
Gene Therapy. 7:1840-1846
We have previously shown that systemic injection of multiple low doses of recombinant murine interleukin-4 (mIL-4) can prevent type 1 diabetes (T1D) in nonobese diabetic (NOD) mice by activating regulatory T helper (Th) 2 cells in vivo. Here, we have
Publikováno v:
Advances in experimental medicine and biology. 520
Autor:
M J, Cameron, G A, Arreaza, P, Zucker, S W, Chensue, R M, Strieter, S, Chakrabarti, T L, Delovitch
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(10)
Beginning at the time of insulitis, nonobese diabetic (NOD) mice demonstrate a thymocyte and peripheral T cell proliferative hyporesponsiveness induced by TCR cross-linking, which is associated with reduced IL-2 and IL-4 secretion. We previously repo
Autor:
Atsuo Ochi, B. M. Gill, Jian Zhang, Mark J. Cameron, G A Arreaza, Terry L. Delovitch, Konstantin V. Salojin
Publikováno v:
The Journal of Experimental Medicine
Nonobese diabetic (NOD) mouse thymocytes are hyporesponsive to T cell antigen receptor (TCR)-mediated stimulation of proliferation, and this T cell hyporesponsiveness may be causal to the onset of autoimmune diabetes in NOD mice. We previously showed
Publikováno v:
Critical reviews in immunology. 17(5-6)
T cells from NOD mice display an age-dependent, TCR-inducible proliferative hyporesponsiveness that may be causal to IDDM. Exogenous IL-4 completely restores this hyporesponsiveness in vitro and prevents IDDM in vivo when administered to NOD mice. We
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Publikováno v:
G.E.N. 31(4)
The authors used Toluidine Blue to stain gastric lesions in nine patients. Six cases were found with adenocarcinoma that stained an intense blue that was limited to the extension of the malignancy itself. The other three cases did not stain and their
Autor:
Salazar González, Milagros1 milasantiago1969@gmail.com, Navarro Nápoles, Josefa2, Quintana Tamayo, Olga Lidia1, Díaz Fondén, Jesús3
Publikováno v:
MEDISAN. 2021, Vol. 25 Issue 2, p265-277. 13p.