Zobrazeno 1 - 10 of 465 pro vyhledávání: '"G A, van der Marel"'
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Synthetic Oligomers Mimicking Capsular Polysaccharide Diheteroglycan are Potential Vaccine Candidates against Encapsulated Enterococcal Infections
Autor: Cecilia Martini, Dmitry A. Argunov, Nikolay E. Nifantiev, Riccardo Torelli, G. A. Van Der Marel, Jeroen D. C. Codée, Ermioni Kalfopoulou, Vadim B. Krylov, Maurizio Sanguinetti, Jacopo Enotarpi, Diana Laverde, Felipe Romero-Saavedra, Johannes Huebner
Publikováno v: ACS Infectious Diseases, 6(7), 1816-1826
Infections caused by Enterococcus spp., are a major concern in the clinical setting. In Enterococcus faecalis, the capsular polysaccharide diheteroglycan (DHG), composed of ß-D-galactofuranose-(1→3)-ß-D-glucopyranose repeats, has been described a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749b837647b573304890a73ee3b173a9
http://hdl.handle.net/10807/178793
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3
Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining α-L-Arabinofuranosidases
Autor: Jean-Guy Berrin, Jos Reijngoud, Marie-Noëlle Rosso, D. Linzel, Herman S. Overkleeft, Alba Nin-Hill, Gideon J. Davies, G. A. Van Der Marel, G.P. van Wezel, Jeroen D. C. Codée, Marta Artola, Mireille Haon, Carme Rovira, Arthur F. J. Ram, Nicholas McGregor
Publikováno v: Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2020, ⟨10.1021/jacs.9b11351⟩
Journal of the American Chemical Society, 142(10), 4648-4662
Journal of the American Chemical Society, 2020, ⟨10.1021/jacs.9b11351⟩
Identifying and characterizing the enzymes responsible for an observed activity within a complex eukaryotic catabolic system remains one of the most significant challenges in the study of biomass-degrading systems. The debranching of both complex hem
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934d42b8426e125ab3c7e4e95a374cf4
https://hal.archives-ouvertes.fr/hal-02482205
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4
Simultaneous quantitation of sphingoid bases by UPLC-ESI-MS/MS with identical13C-encoded internal standards
Autor: Maria J. Ferraz, Jeroen D. C. Codée, Kassiani Kytidou, André R. A. Marques, P. Gaspar, Patrick Wisse, Mina Mirzaian, G. A. Van Der Marel, Johannes M. F. G. Aerts, Saskia V. Oussoren, Herman S. Overkleeft
Publikováno v: Clinica chimica acta; international journal of clinical chemistry, 466, 178-184. Elsevier
Clinica Chimica Acta, 466, 178-184
Free sphingoid bases (lysosphingolipids) of primary storage sphingolipids are increased in tissues and plasma of several sphingolipidoses. As shown earlier by us, sphingoid bases can be accurately quantified using UPLC-ESI-MS/MS, particularly in comb
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::770fcaaf3e459a9a3eed8ccfc1875d8f
https://hdl.handle.net/10400.18/5462
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5
Ring-Extended Gramicidin S Analogs Containingcis δ-Sugar Amino Acid Turn Mimetics with Varying Ring Size
Autor: E. Spalburg, A.J. de Neeling, Gijsbert M. Grotenbreg, Daan Noort, Roos H. Mars-Groenendijk, Hermen S. Overkleeft, Annemiek D. Knijnenburg, Mark Overhand, G. A. Van Der Marel
Publikováno v: Helvetica Chimica Acta. 95:2544-2561
This article presents a series of ring-extended gramicidin S derivatives, 9-14, that have four ornithine residues as polar protonated side chains and one modified turn region containing a mono-functionalized cis-δ-oxetane, δ-furanoid, or δ-pyranoi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b532d020ae0c08c196ef2165a7433920
https://doi.org/10.1002/hlca.201200497
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6
‘Inverted’ analogs of the antibiotic gramicidin S with an improved biological profile
Autor: Daan Noort, M.J. van Raaij, Annemiek D. Knijnenburg, A.J. de Neeling, Roos H. Mars-Groenendijk, Emile Spalburg, José M. Otero, Herman S. Overkleeft, Antonio L. Llamas-Saiz, P. Keizer, Varsha V. Kapoerchan, Mark Overhand, G. A. Van Der Marel
Publikováno v: Bioorganic & Medicinal Chemistry. 20:6059-6062
A series of gramicidin S derivatives 4-15 are presented that have four ornithine residues as polar protonated side chains and two central hydrophobic amino acids with unaltered turn regions. These peptides were screened against human erthrocytes and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c2c965e08ca04008f2834daa32239d
https://doi.org/10.1016/j.bmc.2012.08.038
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7
Synthesis of a spacer-containing trimeric fragment of the capsular polysaccharide from Escherichia coli K100
Autor: H. J. Muntendam, C. J. J. Elie, J. H. Van Boom, G. van de Werken, P. Hoogerhout, G. A. Van Der Marel
Publikováno v: Recueil des Travaux Chimiques des Pays-Bas. 109:467-473
Stereoselective β-glycosidation of 1,3,4-tri-O-benzyl-5-O-pivaloyl-D-ribitol, prepared from L-ribose, with 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose gave, after protecting-group manipulations, the properly protected terminal and non-terminal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63cd2f6998da28026ef86f9f841f16bd
https://doi.org/10.1002/recl.19901090904
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8
Solid-phase synthesis of RNA via a silyl-protecting-group strategy
Autor: C.M. Dreef-Tromp, E. M. A. van Dam, J. H. Van Boom, H. Van Den Elst, G. A. Van Der Marel, J. E. van den Boogaart
Publikováno v: Recueil des Travaux Chimiques des Pays-Bas. 110:378-383
Ribonucleoside phosphoramidites have been prepared of which the exocyclic amino functions and 2′-hydroxyl functions are protected with 2-[(tert-butyldiphenylsiloxy)methyl]benzoyl groups and tert-butyldimethylsilyl groups, respectively. The N-SiOMB/
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8adddfff2c8d8e2827912298810d0a28
https://doi.org/10.1002/recl.19911100905
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9
Synthesis of a potential enzyme-specific inhibitor of squalene synthase
Autor: G. A. Van Der Marel, E. de Kant, S. Hagens, R. de Haan, A. R. P. M. Valentijn, J. H. Van Boom, L.H. Cohen
Publikováno v: Recueil des Travaux Chimiques des Pays-Bas. 114:332-336
A multi-step synthesis of phosphinylphosphonate analogue 12 of the proposed farnesyl-farnesyl-enzyme (FFE) intermediate in the enzymatic conversion of farnesyl pyrophosphate to squalene is described. In addition, evidence is presented of the inhibito
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a8c6e0486d89668b8dadd182930a68f
https://doi.org/10.1002/recl.19951140707
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10
A study on the use of phenylacetyl disulfide in the solid-phase synthesis of oligodeoxynucleoside phosphorothioates
Autor: H. C. P. F. Roelen, Paul C. J. Kamer, J. H. Van Boom, H. Van Den Elst, G. A. Van Der Marel
Publikováno v: Recueil des Travaux Chimiques des Pays-Bas. 110:325-331
Sulfurization of protected [i.e., 2-cyanoethyl, methyl and 2-(4-nitrophenyl)ethyl] internucleosidic phosphite triesters can be conveniently executed with the easily accessible reagent, phenylacetyl disulfide (1). High-quality oligodeoxynucleotides co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4f34853888584176aa91853953ae70f
https://doi.org/10.1002/recl.19911100705
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