Zobrazeno 1 - 8 of 8 pro vyhledávání: '"G A, Wiggan"'
1
Functional contributions of the FcepsilonRIalpha and FepsilonRIgamma subunit domains in FcepsilonRI-mediated signaling in mast cells
Autor: B Repetto, G Bandara, H Kado-Fong, J D Larigan, G A Wiggan, D Pocius, M Basu, A M Gilfillan, J P Kochan
Publikováno v: The Journal of Immunology. 156:4876-4883
The functional contributions of the alpha and gamma subunit domains of the high affinity receptor for IgE (Fcepsilon-RI) were determined following chimeric receptor aggregation. Chimeric receptors of the extracellular (EC) and cytoplasmic tail (CT) d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec21c9607193310d1ed09ec911236230
https://doi.org/10.4049/jimmunol.156.12.4876
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2
Conservation of signal transduction mechanisms via the human Fc epsilon RI alpha after transfection into a rat mast cell line, RBL 2H3
Autor: A M Gilfillan, H Kado-Fong, G A Wiggan, J Hakimi, U Kent, J P Kochan
Publikováno v: The Journal of Immunology. 149:2445-2451
The high affinity receptor for IgE (Fc epsilon RI) is present on mast cells and basophils, and the aggregation of IgE-occupied receptors by Ag is responsible for the release of allergic mediators. The Fc epsilon RI is composed of at least three diffe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c1d0887f43a0d73662d31e04ad8e66e
https://doi.org/10.4049/jimmunol.149.7.2445
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3
Activation of phospholipase D in a rat mast (RBL 2H3) cell line. A possible unifying mechanism for IgE-dependent degranulation and arachidonic acid metabolite release
Autor: P Y Lin, G A Wiggan, A M Gilfillan
Publikováno v: The Journal of Immunology. 146:1609-1616
RBL 2H3 cells (a model of mast cell function) were sensitized with anti-TNP IgE (0.5 micrograms/ml) and triggered to secrete both histamine and arachidonic acid (AA) metabolites by the addition of TNP-OVA (0 to 100 ng/ml). After a 3-min delay, the re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6477374350833166e83a02256f13327e
https://doi.org/10.4049/jimmunol.146.5.1609
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4
The effects of the protein kinase C inhibitors staurosporine and H7 on the IgE dependent mediator release from RBL 2H3 cells
Autor: Ann F. Welton, G. A. Wiggan, A. M. Gilfillan
Publikováno v: Agents and Actions. 30:418-425
RBL 2H3 cells, a model for mast cell function, sensitized with rat IgE, released histamine and peptidoleukotrienes (LT) in response to rabbit anti-rat IgE in a concentration-dependent manner. The calcium ionophore, A23187 also stimulated the release
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90336686f25b869c7b70efd13ff8e040
https://doi.org/10.1007/bf01966307
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5
Functional contributions of the FcepsilonRIalpha and FepsilonRIgamma subunit domains in FcepsilonRI-mediated signaling in mast cells
Autor: B, Repetto, G, Bandara, H, Kado-Fong, J D, Larigan, G A, Wiggan, D, Pocius, M, Basu, A M, Gilfillan, J P, Kochan
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 156(12)
The functional contributions of the alpha and gamma subunit domains of the high affinity receptor for IgE (Fcepsilon-RI) were determined following chimeric receptor aggregation. Chimeric receptors of the extracellular (EC) and cytoplasmic tail (CT) d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a3565208a1f8fcb9321fceac81e8e8ce
https://pubmed.ncbi.nlm.nih.gov/8648137
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6
Functional characterization of the signal transduction events mediated by Fc epsilon RI alpha and gamma chimeric receptors
Autor: B, Repetto, G, Bandara, G A, Wiggan, A M, Gilfillan, J P, Kochan
Publikováno v: International archives of allergy and immunology. 107(1-3)
Chimeric receptors containing the Fc epsilon RI alpha and gamma subunit domains were constructed, stably transfected into RBL-2H3 cells, and characterized for the biochemical events which are elicited upon receptor aggregation. Chimeric receptors con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c1db3369491f4fb392ae12d27dab2e65
https://pubmed.ncbi.nlm.nih.gov/7542105
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7
Conservation of signal transduction mechanisms via the human Fc epsilon RI alpha after transfection into a rat mast cell line, RBL 2H3
Autor: A M, Gilfillan, H, Kado-Fong, G A, Wiggan, J, Hakimi, U, Kent, J P, Kochan
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 149(7)
The high affinity receptor for IgE (Fc epsilon RI) is present on mast cells and basophils, and the aggregation of IgE-occupied receptors by Ag is responsible for the release of allergic mediators. The Fc epsilon RI is composed of at least three diffe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f7ca51a4f1a51fd6852f39393b1324cd
https://pubmed.ncbi.nlm.nih.gov/1382104
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8
Activation of phospholipase D in a rat mast (RBL 2H3) cell line. A possible unifying mechanism for IgE-dependent degranulation and arachidonic acid metabolite release
Autor: P Y, Lin, G A, Wiggan, A M, Gilfillan
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 146(5)
RBL 2H3 cells (a model of mast cell function) were sensitized with anti-TNP IgE (0.5 micrograms/ml) and triggered to secrete both histamine and arachidonic acid (AA) metabolites by the addition of TNP-OVA (0 to 100 ng/ml). After a 3-min delay, the re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ad2c0d97c068615f1c515229eb87bb60
https://pubmed.ncbi.nlm.nih.gov/1704399
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