Zobrazeno 1 - 10
of 46
pro vyhledávání: '"G A, Weisman"'
Autor:
G. R. Weisman, D. P. Reed
Publikováno v:
ChemInform. 27
Publikováno v:
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... 52(2)
Copper-64 (t(1/2)=12.7 h; beta+: 17.4%; E(beta+max)=656 keV; beta-: 39%; E(beta-max)=573 keV) has emerged as an important non-standard positron-emitting radionuclide for positron emission tomography imaging of diseased tissues. A significant challeng
Autor:
L I, Santiago-Pérez, R V, Flores, C, Santos-Berríos, N E, Chorna, B, Krugh, R C, Garrad, L, Erb, G A, Weisman, F A, González
Publikováno v:
Journal of cellular physiology. 187(2)
Activation of P2Y(2) receptors by extracellular nucleotides has been shown to induce phenotypic differentiation of human promonocytic U937 cells that is associated with the inflammatory response. The P2Y(2) receptor agonist, UTP, induced the phosphor
Publikováno v:
Molecular and cellular biochemistry. 206(1-2)
The equal potency and efficacy of the agonists, ATP and UTP, pharmacologically distinguish the P2Y2 receptor from other nucleotide receptors. Investigation of the desensitization of the P2Y2 receptors is complicated by the simultaneous expression of
Autor:
M, Otero, R C, Garrad, B, Velázquez, M G, Hernández-Pérez, J M, Camden, L, Erb, L L, Clarke, J T, Turner, G A, Weisman, F A, González
Publikováno v:
Molecular and cellular biochemistry. 205(1-2)
UTP activates P2Y, receptors in both 1321N1 cell transfectants expressing the P2Y2 receptor and human HT-29 epithelial cells expressing endogenous P2Y, receptors with an EC50 of 0.2-1.0 microM. Pretreatment of these cells with UTP diminished the effe
Publikováno v:
Progress in brain research. 120
Salivary gland nucleotide receptors: evidence for functional expression of both P2X and P2Y subtypes
Publikováno v:
European journal of morphology.
A growing body of information now supports the suggestion that P2 receptors for extracellular nucleotides (primarily ATP) have a role in regulating salivary gland function. There is solid pharmacological and molecular evidence for the presence of P2X
Autor:
R C, Garrad, M A, Otero, L, Erb, P M, Theiss, L L, Clarke, F A, Gonzalez, J T, Turner, G A, Weisman
Publikováno v:
The Journal of biological chemistry. 273(45)
Molecular determinants of P2Y2 receptor desensitization and sequestration have been investigated. Wild-type P2Y2 receptors and a series of five C-terminal truncation mutants of the receptor were epitope-tagged and stably expressed in 1321N1 cells. Th
Publikováno v:
Advances in experimental medicine and biology. 431
Publikováno v:
Journal of neuroscience research. 49(1)
P2 nucleotide receptor expression in cultured human retinal pigment epithelial (RPE) cells was investigated using the photoaffinity ATP analog BzATP, polymerase chain reaction of reverse-transcribed RNA (RT-PCR) and fura-2 fluorescence measurement of