Zobrazeno 1 - 10
of 116
pro vyhledávání: '"G A, Serebrennikova"'
Publikováno v:
Тонкие химические технологии, Vol 7, Iss 6, Pp 27-31 (2012)
Synthetic approaches to obtain diglycerides containing polyunsaturated fatty acids at C(2 ) position of glycerol were developed. These compounds can be used to generate antitumor lipids and enzymatically triggered liposomes .
Externí odkaz:
https://doaj.org/article/ea05ce2918dc425298c7fe5a15407b6c
Publikováno v:
Тонкие химические технологии, Vol 6, Iss 5, Pp 72-86 (2011)
Synthesis and biological activities of both cationic and neutral amphiphiles for the development of systems for nucleic acids delivery into eukaryotic cells have been discussed
Externí odkaz:
https://doaj.org/article/70d17276adbb4c1183d242823fc4634c
Publikováno v:
Тонкие химические технологии, Vol 5, Iss 6, Pp 58-62 (2010)
A synthesis of polycationic amphiphiles on the basis of cholic acis with potential antimicrobial and transfection activities has been described.
Externí odkaz:
https://doaj.org/article/f6bcfd5f7bc44ea5988cc23ace313a62
Publikováno v:
Тонкие химические технологии, Vol 5, Iss 5, Pp 65-70 (2010)
The synthesis of galactose-containing amphiphiles based on tetradecanol, cholesterol or 1,2-di-O-tetradecylglycerol has been described. The compounds synthesized can be used as components of liposomal targeted carries for therapeutics delivery into l
Externí odkaz:
https://doaj.org/article/dbd00121f2f04b2aa6fb1449d80509a7
Publikováno v:
Тонкие химические технологии, Vol 3, Iss 5, Pp 104-108 (2008)
The synthesis of new cationic ether glycerolipids, non-phosphoros analogues of edelfosine. Are investigated cytotixic properties and hemolytic activity of the synthesized substances.
Externí odkaz:
https://doaj.org/article/39f508b328134848a3e16a0017dd7642
Publikováno v:
Тонкие химические технологии, Vol 3, Iss 4, Pp 53-57 (2008)
The synthesis of new non-phosphorus ether glycerolipids containing a pyridinium ring in a polar domain is described. Novel compounds possess high cytotoxic activity against human leukemia К562 and colon cancer HCT116 cell lines.
Externí odkaz:
https://doaj.org/article/bcde371114fc47ec8eb103738bab6a66
Publikováno v:
Тонкие химические технологии, Vol 1, Iss 4, Pp 55-58 (2006)
A convenient approach for synthesis of both neutral and cationic carbohydratebased amphiphiles has been elaborated. Compounds synthesized intended for target delivery of pharmaceutical substances into eukaryotic cells.
Externí odkaz:
https://doaj.org/article/ff4d06760e15400f99737842b3694007
Autor:
Valentine V. Vlassov, G. A. Serebrennikova, Tatyana O. Kabilova, Marina A. Zenkova, Mikhail A. Maslov, Nina G. Morozova, Ivan A. Petukhov
Publikováno v:
Journal of Controlled Release. 160:182-193
New polycationic lipids corresponding to the two different classes of amphiphiles (“head-tail” and “gemini”) were designed and used as components of non-viral gene delivery systems. The hydrophobic domain of lipids is based on the cholesterol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5299267a9d04e1438d96a040b38c9ec9
https://doi.org/10.1016/j.jconrel.2011.11.023
https://doi.org/10.1016/j.jconrel.2011.11.023
Publikováno v:
Russian Journal of Bioorganic Chemistry. 37:492-498
Synthesis of new cationic alkyl glycerolipids with potential antitumor properties is described, their polar domain being heterocyclic nitrogen-containing bases of various types. A synthetic scheme for cationic lipids containing aliphatic short-chain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8996ee777c7b4a8a1929ff6f03e738a5
https://doi.org/10.1134/s1068162011040108
https://doi.org/10.1134/s1068162011040108
Autor:
Marina A. Zenkova, Rapoport Da, Roman N. Serikov, G. A. Serebrennikova, N. G. Morozova, D.A. Medvedeva, Mikhail A. Maslov, Valentin V. Vlassov
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:2937-2940
In this study, we synthesized a new galactosylated cationic lipid and investigated its biological activity. The structure of lipid combines both spermine residue for DNA compaction and galactose moiety for the improvement of aggregation behavior of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2405e6622aedec7bfacf23fa986bd66
https://doi.org/10.1016/j.bmcl.2011.03.056
https://doi.org/10.1016/j.bmcl.2011.03.056