Zobrazeno 1 - 10
of 22
pro vyhledávání: '"G A, Piazza"'
Autor:
C. Damsa, P. Groff, Antonio Andreoli, Charles B. Pull, I. Chauvet, G. Di Piazza, T. Di Clemente
Publikováno v:
Annales Médico-psychologiques, revue psychiatrique. 162:140-143
L'interet d'une revue de la litterature concernantles liens possibles entre les troubles bipolaires et une betathalassemie a ete suscite par deux observations cliniques. Plusieurs cas ont ete decrits dans la litterature, suggerant un lien existant en
Autor:
Peter R. Holt, Christopher M. Weghorst, Thomas Delohery, N Arber, Dennis J. Ahnen, G. A. Piazza, N.-H. Kim, J. C. Reed, E. K.-H. Han, R. Pamukcu, Martin Begemann, Alessandro Sgambato, I. B. Weinstein
Publikováno v:
Gastroenterology. 113:1892-1900
BACKGROUND & AIMS: Mutations of c-K-ras occur commonly in colonic neoplasms. The aim of this study was to determine how c-K-ras mutations alter the responses to the chemopreventive agent sulindac. METHODS: The parental rat intestinal cell line IEC-18
Autor:
G A, Piazza, W J, Thompson, R, Pamukcu, H W, Alila, C M, Whitehead, L, Liu, J R, Fetter, W E, Gresh, A J, Klein-Szanto, D R, Farnell, I, Eto, C J, Grubbs
Publikováno v:
Cancer research. 61(10)
Exisulind (Aptosyn) is a novel antineoplastic drug being developed for the prevention and treatment of precancerous and malignant diseases. In colon tumor cells, the drug induces apoptosis by a mechanism involving cyclic GMP (cGMP) phosphodiesterase
Publikováno v:
Biochemical Society transactions. 28(6)
The micro-alga Chlorella pyrenoidosa expresses an enzymatic activity that cleaves the 13-hydroperoxide derivatives of linoleic acid [13-hydroperoxy-9(Z),11(E)-octadecadienoic acid, 13-HPOD] and linolenic acid [13-hydroperoxy-9(Z),11(E),15(Z)-octadeca
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 9(11)
The nonsteroidal anti-inflammatory drug sulindac and the ornithine decarboxylase inhibitor difluoromethylornithine (DFMO) are both potent inhibitors of colon carcinogenesis in experimental models of this disease. The combination of these two agents i
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(10)
Sulindac sulfone (Exisulind) induces apoptosis and exhibits cancer chemopreventive activity, but in contrast to sulindac, it does not inhibit cyclooxygenases 1 or 2. We found that sulindac sulfone and two potent derivatives, CP248 and CP461, inhibite
Publikováno v:
Cancer research. 60(13)
Sulindac sulfone (exisulind), although a nonsteroidal anti-inflammatory drug derivative, induces apoptosis in tumor cells by a mechanism that does not involve cyclooxygenase inhibition. SW480 colon tumor cells contain guanosine 3',5'-monophosphate (c
Autor:
E, Skopińska-Rózewska, G A, Piazza, E, Sommer, R, Pamukcu, E, Barcz, M, Filewska, W, Kupis, R, Caban, P, Rudziński, J, Bogdan, S, Mlekodaj, E, Sikorska
Publikováno v:
International journal of tissue reactions. 20(3)
The nonsteroidal antiinflammatory drug sulindac (sulfoxide) is known to cause regression and prevent recurrence of adenomas in patients with familial adenomatous polyposis. The mechanism of action does not appear to require inhibition of prostaglandi
Autor:
G A, Piazza, D S, Alberts, L J, Hixson, N S, Paranka, H, Li, T, Finn, C, Bogert, J M, Guillen, K, Brendel, P H, Gross, G, Sperl, J, Ritchie, R W, Burt, L, Ellsworth, D J, Ahnen, R, Pamukcu
Publikováno v:
Cancer research. 57(14)
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as sulindac, have cancer chemopreventive properties by a mechanism that has been suggested to involve cyclooxygenase inhibition and reduction of prostaglandin (PGE2) levels in the target tissue. To
Publikováno v:
Cancer research. 57(12)
Sulindac causes regression of and prevents recurrence of colonic adenomas in patients with familial adenomatous polyposis. Although cell cycle arrest and apoptosis have been proposed, the mechanism of action is poorly understood. In this study, we ch