Investigation of Liver X Receptor Gene Variants and Oxysterol Dysregulation in Autism Spectrum Disorder

Autor: Tuğba Menteşe Babayiğit, Güvem Gümüş-Akay, Merve Çikili Uytun, Özlem Doğan, Muhittin A. Serdar, Gökçe Yağmur Efendi, Ayşe Gökçe Erman, Esra Yürümez, Didem Behice Öztop

Publikováno v: Children, Vol 11, Iss 5, p 551 (2024)

The NR1H2 gene produces the Liver X Receptor Beta (LXRB) protein, which is crucial for brain cholesterol metabolism and neuronal development. However, its involvement in autism spectrum disorder (ASD) remains largely unexplored, aside from animal stu

Externí odkaz: https://doaj.org/article/b62dbb8bfd424f95b5ab9d030f60df1a

Examining the association between exposome score for schizophrenia and functioning in schizophrenia, siblings, and healthy controls: Results from the EUGEI study

Autor: Gamze Erzin, Lotta-Katrin Pries, Jim van Os, Laura Fusar-Poli, Philippe Delespaul, Gunter Kenis, Jurjen J. Luykx, Bochao D. Lin, Alexander L. Richards, Berna Akdede, Tolga Binbay, Vesile Altınyazar, Berna Yalınçetin, Güvem Gümüş-Akay, Burçin Cihan, Haldun Soygür, Halis Ulaş, Eylem Şahin Cankurtaran, Semra Ulusoy Kaymak, Marina M. Mihaljevic, Sanja Andric-Petrovic, Tijana Mirjanic, Miguel Bernardo, Gisela Mezquida, Silvia Amoretti, Julio Bobes, Pilar A. Saiz, Maria Paz García-Portilla, Julio Sanjuan, Eduardo J. Aguilar, Jose Luis Santos, Estela Jiménez-López, Manuel Arrojo, Angel Carracedo, Gonzalo López, Javier González-Peñas, Mara Parellada, Nadja P. Maric, Cem Atbaşoğlu, Alp Ucok, Köksal Alptekin, Meram Can Saka, Celso Arango, Micheal C. O’Donovan, Bart P. F. Rutten, Sinan Guloksuz

Publikováno v: European Psychiatry, Vol 64 (2021)

AbstractBackgroundA cumulative environmental exposure score for schizophrenia (exposome score for schizophrenia [ES-SCZ]) may provide potential utility for risk stratification and outcome prediction. Here, we investigated whether ES-SCZ was associate

Externí odkaz: https://doaj.org/article/f07c8f21a535426fb85528b818755e9a

Genetic Analysis of RASD1 as a Candidate Gene for Schizophrenia

Autor: Ceren Damla Durmaz, Halil Gürhan Karabulut, Meram Can Saka, Ceren Sucularlı, Güvem Gümüş Akay, Cem Atbaşoğlu, Hatice Ilgın Ruhi

Publikováno v: Balkan Medical Journal. 39:422-428

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec99dc311d254ea0d05ef410055fefb2
https://doi.org/10.4274/balkanmedj.galenos.2022.2022-5-90

Genetic Analysis of

Autor: Ceren Damla, Durmaz, Halil Gürhan, Karabulut, Meram Can, Saka, Ceren, Sucularlı, Güvem, Gümüş Akay, Cem, Atbaşoğlu, Hatice, Ilgın Ruhi

Publikováno v: Balkan medical journal. 39(6)

To investigate the association ofA case-control study.We performed targeted sequencing for the two exons, single intron, and untranslated regions ofTwo rare variants,Our findings suggest that rare variants of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::be61a2ae46336d733f4024945f0bff4a
https://pubmed.ncbi.nlm.nih.gov/36305088

A replication study of JTC bias, genetic liability for psychosis and delusional ideation

Autor: Berna Binnur Akdede, Vesile Altınyazar, Angel Carracedo, Sanja S. Petrovic, Gisela Mezquida, Alp Üçok, Berna Yalınçetin, Semra Ulusoy Kaymak, Cécile Henquet, Philippe Delespaul, Michael Conlon O'Donovan, Tijana Mirjanic, Javier González-Peñas, Jim van Os, Sinan Guloksuz, Mara Parellada, Bart P. F. Rutten, Miguel Bernardo, Haldun Soygür, Julio Sanjuán, Burçin Cihan, Pilar A. Saiz, Gonzalo López, Eduardo J. Aguilar, Nadja P. Maric, Gunter Kenis, Christian Rauschenberg, Tolga Binbay, Güvem Gümüş-Akay, Halis Ulaş, Manuel Arrojo, Cem Atbaşoğlu, Jose Luis Santos, Jurjen J. Luykx, Silvia Amoretti, Julio Bobes, Estela Jiménez-López, Alexander Richards, Köksal Alptekin, Lotta K. Pries, Meram Can Saka, Bochao D. Lin, Celso Arango, Marina Mihaljevic, María Paz García-Portilla, Eylem Sahin Cankurtaran

Publikováno v: Psychological Medicine, 52(9):0033291720003578, 1777-1783. Cambridge University Press
Scopus
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
PSYCHOLOGICAL MEDICINE
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA

The EUGEI project was supported by the European Community's Seventh Framework Program under grant agreement No. HEALTH-F2-2009-241909 (Project EU-GEI). Dr O'Donovan is supported by MRC programme grant (G08005009) and an MRC Centre grant (MR/L010305/1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2aace51699d4c685ca4864059449103
https://cris.maastrichtuniversity.nl/en/publications/15dcb95e-0e9c-4e93-b86c-a5c72e876cc0