Investigation of Liver X Receptor Gene Variants and Oxysterol Dysregulation in Autism Spectrum Disorder

Autor: Tuğba Menteşe Babayiğit, Güvem Gümüş-Akay, Merve Çikili Uytun, Özlem Doğan, Muhittin A. Serdar, Gökçe Yağmur Efendi, Ayşe Gökçe Erman, Esra Yürümez, Didem Behice Öztop

Publikováno v: Children, Vol 11, Iss 5, p 551 (2024)

The NR1H2 gene produces the Liver X Receptor Beta (LXRB) protein, which is crucial for brain cholesterol metabolism and neuronal development. However, its involvement in autism spectrum disorder (ASD) remains largely unexplored, aside from animal stu

Externí odkaz: https://doaj.org/article/b62dbb8bfd424f95b5ab9d030f60df1a

White Noise Speech Illusions: A Trait-Dependent Risk Marker for Psychotic Disorder?

Autor: Elaine Schepers, Richel Lousberg, Sinan Guloksuz, Lotta-Katrin Pries, Philippe Delespaul, Gunter Kenis, Jurjen J. Luykx, Bochao D. Lin, Alexander L. Richards, Berna Akdede, Tolga Binbay, Vesile Altınyazar, Berna Yalınçetin, Güvem Gümüş-Akay, Burçin Cihan, Haldun Soygür, Halis Ulaş, Eylem Şahin Cankurtaran, Semra Ulusoy Kaymak, Marina M. Mihaljevic, Sanja Andric Petrovic, Tijana Mirjanic, Miguel Bernardo, Bibiana Cabrera, Julio Bobes, Pilar A. Saiz, María Paz García-Portilla, Julio Sanjuan, Eduardo J. Aguilar, José Luis Santos, Estela Jiménez-López, Manuel Arrojo, Angel Carracedo, Gonzalo López, Javier González-Peñas, Mara Parellada, Nadja P. Maric, Cem Atbaşoğlu, Alp Ucok, Köksal Alptekin, Meram Can Saka, Celso Arango, Bart P.F. Rutten, Jim van Os

Publikováno v: Frontiers in Psychiatry, Vol 10 (2019)

Introduction: White noise speech illusions index liability for psychotic disorder in case–control comparisons. In the current study, we examined i) the rate of white noise speech illusions in siblings of patients with psychotic disorder and ii) to

Externí odkaz: https://doaj.org/article/58c7d9e5e6594a65ad36b3614ff8bca6

Genetic Analysis of

Autor: Ceren Damla, Durmaz, Halil Gürhan, Karabulut, Meram Can, Saka, Ceren, Sucularlı, Güvem, Gümüş Akay, Cem, Atbaşoğlu, Hatice, Ilgın Ruhi

Publikováno v: Balkan medical journal. 39(6)

To investigate the association ofA case-control study.We performed targeted sequencing for the two exons, single intron, and untranslated regions ofTwo rare variants,Our findings suggest that rare variants of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::be61a2ae46336d733f4024945f0bff4a
https://pubmed.ncbi.nlm.nih.gov/36305088

A replication study of JTC bias, genetic liability for psychosis and delusional ideation

Autor: Berna Binnur Akdede, Vesile Altınyazar, Angel Carracedo, Sanja S. Petrovic, Gisela Mezquida, Alp Üçok, Berna Yalınçetin, Semra Ulusoy Kaymak, Cécile Henquet, Philippe Delespaul, Michael Conlon O'Donovan, Tijana Mirjanic, Javier González-Peñas, Jim van Os, Sinan Guloksuz, Mara Parellada, Bart P. F. Rutten, Miguel Bernardo, Haldun Soygür, Julio Sanjuán, Burçin Cihan, Pilar A. Saiz, Gonzalo López, Eduardo J. Aguilar, Nadja P. Maric, Gunter Kenis, Christian Rauschenberg, Tolga Binbay, Güvem Gümüş-Akay, Halis Ulaş, Manuel Arrojo, Cem Atbaşoğlu, Jose Luis Santos, Jurjen J. Luykx, Silvia Amoretti, Julio Bobes, Estela Jiménez-López, Alexander Richards, Köksal Alptekin, Lotta K. Pries, Meram Can Saka, Bochao D. Lin, Celso Arango, Marina Mihaljevic, María Paz García-Portilla, Eylem Sahin Cankurtaran

Publikováno v: Psychological Medicine, 52(9):0033291720003578, 1777-1783. Cambridge University Press
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RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
PSYCHOLOGICAL MEDICINE
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA

The EUGEI project was supported by the European Community's Seventh Framework Program under grant agreement No. HEALTH-F2-2009-241909 (Project EU-GEI). Dr O'Donovan is supported by MRC programme grant (G08005009) and an MRC Centre grant (MR/L010305/1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2aace51699d4c685ca4864059449103
https://cris.maastrichtuniversity.nl/en/publications/15dcb95e-0e9c-4e93-b86c-a5c72e876cc0

Psychometric liability to psychosis and childhood adversities are associated with shorter telomere length

Autor: Alp Üçok, Burcu Sırmatel, Sinan Guloksuz, Burcu Çevik, Güvem Gümüş-Akay, Eşref Cem Atbaşoğlu, Öykü Mançe-Çalışır, Jim van Os, Ajlan Tükün, Meram Can Saka, Köksal Alptekin

Publikováno v: Journal of Psychiatric Research, 111, 169. Elsevier Limited
Journal of Psychiatric Research, 111, 169-185. Elsevier Science

Compared to the general population, individuals diagnosed with Schizophrenia (SCZ) experience a higher frequency and an earlier onset of chronic medical disorders, resulting in a reduction in life expectancy by an average of 15-25 years. Recently, it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae0e999431ae04966a31a611aa39933d
https://cris.maastrichtuniversity.nl/en/publications/f2d2b083-a30b-41e0-ba4b-5a43056bb28b