Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gürdal Şahin"'
Publikováno v:
Balkan Medical Journal, Vol 39, Iss 5, Pp 318-333 (2022)
Parkinson’s disease (PD) is a complex, chronic, and progressive neurodegenerative disease that is characterized by irreversible dopaminergic neuronal loss in the substantia nigra. Alpha-synuclein is normally a synaptic protein that plays a key role
Externí odkaz:
https://doaj.org/article/18f80a5089374386bdc756602273acec
Publikováno v:
Cephalalgia Reports, Vol 7 (2024)
Background There is a growing awareness of constipation being a side effect of anti-calcitonin gene-related peptide (anti-CGRP) monoclonal antibodies (mAbs). This study aims to assess constipation as a side effect and explore its potential role as a
Externí odkaz:
https://doaj.org/article/616079f3cc784d17a17d5b15e375c274
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ObjectiveTo report the efficacy of different anti-calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) on headache frequency, intensity, and duration.BackgroundBlockade of CGRP receptors or neuropeptide with anti-CGRP mAbs have been su
Externí odkaz:
https://doaj.org/article/036c0c66296143a289d037996e512658
Autor:
Gülşen ÖZKAYA ŞAHİN, Gürdal ŞAHİN
Publikováno v:
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Vol 10, Iss 1, Pp 9-13 (2005)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::3486f502989b2471435319047ed6f469
http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2005-10-1-009-013.pdf
http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2005-10-1-009-013.pdf
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Tremor can be highly incapacitating in everyday life and typically fluctuates depending on motor state, medication status as well as external factors. For tremor patients being treated with deep-brain stimulation (DBS), adapting the intensity and pat
Externí odkaz:
https://doaj.org/article/ad8936bdacb3497b8cfa2c1d90a8bca0
Autor:
Fabia Febbraro, Gurdal Sahin, Aina Farran, Sofia Soares, Poul H. Jensen, Deniz Kirik, Marina Romero-Ramos
Publikováno v:
Neurobiology of Disease, Vol 56, Iss , Pp 47-58 (2013)
Alpha-synuclein phosphorylated at serine 129 (S129) is highly elevated in Parkinson's disease patients where it mainly accumulates in the Lewy bodies. Several groups have studied the role of phosphorylation at the S129 in α-synuclein in a rat model
Externí odkaz:
https://doaj.org/article/d0fadbd0a5e146d188a2e3262299e943
Publikováno v:
Neurobiology of Disease, Vol 48, Iss 2, Pp 222-227 (2012)
l-DOPA is currently the standard treatment for alleviating the motor symptoms in Parkinson's disease. The therapeutic efficacy, however, diminishes as the disease progresses. It has been suggested that the beneficial effect of l-DOPA could be reestab
Externí odkaz:
https://doaj.org/article/f2da9c83c4bd41ee888e414903b990c8
Autor:
Gurdal Sahin, Lachlan H Thompson, Sonia Lavisse, Merve Ozgur, Latifa Rbah-Vidal, Frédéric Dollé, Philippe Hantraye, Deniz Kirik
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90759 (2014)
Dyskinesia is a major side effect of an otherwise effective L-DOPA treatment in Parkinson's patients. The prevailing view for the underlying presynaptic mechanism of L-DOPA-induced dyskinesia (LID) suggests that surges in dopamine (DA) via uncontroll
Externí odkaz:
https://doaj.org/article/7a39cbc361044a258d20cb9a92cbb3b7
Autor:
Fabia Febbraro, Gurdal Sahin, Aina Farran, Sofia Soares, Poul H. Jensen, Deniz Kirik, Marina Romero-Ramos
Publikováno v:
Neurobiology of Disease, Vol 58, Iss , Pp 191- (2013)
Externí odkaz:
https://doaj.org/article/d3f3021cc9f5496ca743618795a895d2