Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Güralp O. Ceyhan"'
Autor:
Lei Ren, MD, Carsten Jäger, MPH, Stephan Schorn, Ilaria Pergolini, Rüdiger Göß, Okan Safak, Maximilian Kießler, Marc E. Martignoni, Alexander R. Novotny, Helmut Friess, Güralp O. Ceyhan, Ihsan Ekin Demir
Publikováno v:
Annals of Surgery Open, Vol 4, Iss 3, p e302 (2023)
Background:. Arterial resection (AR) during pancreatectomy for curative R0 resection of pancreatic ductal adenocarcinoma (PDAC) remains a controversial procedure with high morbidity. Objective:. To investigate the feasibility and oncological outcomes
Externí odkaz:
https://doaj.org/article/a0a7376ec8a24c4fa86e22a8b7ac848b
Autor:
Elke Demir, Bengi Su Yilmaz, Carsten Jäger, Kathrin Rothe, Stephan Schorn, Ilaria Pergolini, Rüdiger Göß, Okan Safak, Dirk Wilhelm, Marc E. Martignoni, Alexander R. Novotny, Helmut Friess, Güralp O. Ceyhan, Ihsan Ekin Demir
Publikováno v:
Heliyon, Vol 8, Iss 11, Pp e11771- (2022)
Background: Pancreatic fistula/PF is a challenging surgical complication. We could recently show that intestinal bacteria such as Enterobacterales colonize the PF fluid even after a “sterile” operation like distal pancreatectomy/DP. Therefore, we
Externí odkaz:
https://doaj.org/article/4ddd9e8b18124d16821619121881b951
Autor:
H. Erdinc Besikcioglu, Ümmügülsüm Yurteri, Enkhtsetseg Munkhbaatar, Linhan Ye, Fangfang Zhang, Alessandra Moretti, Carmen Mota Reyes, Candan Özoğul, Helmut Friess, Güralp O. Ceyhan, Rouzanna Istvanffy, Ihsan Ekin Demir
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100935- (2021)
Summary: Pancreatic cancer is characterized by bi-directional interactions between pancreatic cancer cells and stromal cells including neural cells. The absence of neural cells in pancreatic organoids limits the investigation of cell- cell interactio
Externí odkaz:
https://doaj.org/article/b642699e60d54a329d6538dd1f56fe16
Autor:
Ihsan Ekin Demir, Tobias Heinrich, Dominique G. Carty, Ömer Cemil Saricaoglu, Sarah Klauss, Steffen Teller, Timo Kehl, Carmen Mota Reyes, Elke Tieftrunk, Maria Lazarou, Dorukhan H. Bahceci, Betül Gökcek, Bahar E. Ucurum, Matthias Maak, Kalliope N. Diakopoulos, Marina Lesina, Michael Schemann, Mert Erkan, Achim Krüger, Hana Algül, Helmut Friess, Güralp O. Ceyhan
Publikováno v:
EBioMedicine, Vol 46, Iss , Pp 431-443 (2019)
Background: Pain due to pancreatic cancer/PCa or chronic pancreatitis/CP, is notoriously resistant to the strongest pain medications. Here, we aimed at deciphering the specific molecular mediators of pain at surgical-stage pancreatic disease and to d
Externí odkaz:
https://doaj.org/article/e5b83526ca9647e8bb16e16a99287a55
Autor:
Tamara Zietek, Pieter Giesbertz, Maren Ewers, Florian Reichart, Michael Weinmüller, Elisabeth Urbauer, Dirk Haller, Ihsan Ekin Demir, Güralp O. Ceyhan, Horst Kessler, Eva Rath
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Intestinal transport and sensing processes and their interconnection to metabolism are relevant to pathologies such as malabsorption syndromes, inflammatory diseases, obesity and type 2 diabetes. Constituting a highly selective barrier, intestinal ep
Externí odkaz:
https://doaj.org/article/90bbb30042a94fc589fa4b26de6ad238
Autor:
Ziying Jian, Tao Cheng, Zhiheng Zhang, Susanne Raulefs, Kuangyu Shi, Katja Steiger, Nadja Maeritz, Karin Kleigrewe, Thomas Hofmann, Simone Benitz, Philipp Bruns, Daniel Lamp, Martin Jastroch, Jan Akkan, Carsten Jäger, Peilin Huang, Shuang Nie, Shanshan Shen, Xiaoping Zou, Güralp O. Ceyhan, Christoph W. Michalski, Helmut Friess, Jörg Kleeff, Bo Kong
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 4, Pp 429-449 (2018)
Background & Aims: Although nearly half of pancreatic ductal adenocarcinoma (PDAC) patients have diabetes mellitus with episodes of hyperglycemia, its tumor microenvironment is hypoglycemic. Thus, it is crucial for PDAC cells to develop adaptive mech
Externí odkaz:
https://doaj.org/article/a2ff2b7c8a4e4563ac1a648e6adcb65c
Autor:
Søren S. Olesen, Theresa Krauss, Ihsan Ekin Demir, Oliver H. Wilder-Smith, Güralp O. Ceyhan, Pankaj J. Pasricha, Asbjørn M. Drewes
Publikováno v:
PAIN Reports, Vol 2, Iss 6, p e625 (2017)
Abstract. Introduction:. Chronic pancreatitis (CP) is a disease characterized by inflammation of the pancreas resulting in replacement of the normal functioning parenchyma by fibrotic connective tissue. This process leads to progressively impairment
Externí odkaz:
https://doaj.org/article/1f689f79d76a47d7a05279d33d0768b3
Autor:
Sabine Buhner, Natasja Barki, Wolfgang Greiter, Pieter Giesbertz, Ihsan E. Demir, Güralp O. Ceyhan, Florian Zeller, Hannelore Daniel, Michael Schemann
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Introduction: It is suggested that an altered microenvironment in the gut wall alters communication along a mast cell nerve axis. We aimed to record for the first time signaling between mast cells and neurons in intact human submucous preparations.Me
Externí odkaz:
https://doaj.org/article/5faee36039444cff94f06ae5f49b05a3
Autor:
Ihsan Ekin Demir, Güralp O. Ceyhan, Helmut Friess, Wilko Weichert, Okan Safak, Björn Konukiewitz, Alexander Muckenhuber, Steffen Teller, Carmen Mota Reyes
Supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f892aa6260fe7dad026278da6c2e8e
https://doi.org/10.1158/1078-0432.22473180
https://doi.org/10.1158/1078-0432.22473180
Autor:
Wilko Weichert, Christoph Springfeld, Dirk Jäger, Martin R. Sprick, Albrecht Stenzinger, Marcus Bahra, Carsten Denkert, Moritz Jesinghaus, Güralp O. Ceyhan, Günter Klöppel, Irene Esposito, Helmut Friess, Jens Werner, Roland Eils, Andreas Trumpp, Björn Konukiewitz, Katja Steiger, Anna Melissa Schlitter, Anne Katrin Berger, Alexander Muckenhuber
Frequency distributions of IHC-derived subtypes of PDAC and unclassifiable cases (purple) in all cohorts investigated in this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59aa8cd3039e525b2c7965071522da1
https://doi.org/10.1158/1078-0432.22466028.v1
https://doi.org/10.1158/1078-0432.22466028.v1