Výsledky vyhledávání - "Günther M. Keil"

Akademický článek

Identification of African swine fever virus-like elements in the soft tick genome provides insights into the virus’ evolution

Autor: Jan H. Forth, Leonie F. Forth, Samantha Lycett, Lesley Bell-Sakyi, Günther M. Keil, Sandra Blome, Sébastien Calvignac-Spencer, Antje Wissgott, Johannes Krause, Dirk Höper, Helge Kampen, Martin Beer

Publikováno v: BMC Biology, Vol 18, Iss 1, Pp 1-18 (2020)

Abstract Background African swine fever virus (ASFV) is a most devastating pathogen affecting swine. In 2007, ASFV was introduced into Eastern Europe where it continuously circulates and recently reached Western Europe and Asia, leading to a socio-ec

Externí odkaz: https://doaj.org/article/026be12c963e40d99105dfb9e6f96966

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Akademický článek

Serological Hendra Virus Diagnostics Using an Indirect ELISA-Based DIVA Approach with Recombinant Hendra G and N Proteins

Autor: Anne Balkema-Buschmann, Kerstin Fischer, Leanne McNabb, Sandra Diederich, Nagendrakumar Balasubramanian Singanallur, Ute Ziegler, Günther M. Keil, Peter D. Kirkland, Maren Penning, Balal Sadeghi, Glenn Marsh, Jennifer Barr, Axel Colling

Publikováno v: Microorganisms, Vol 10, Iss 6, p 1095 (2022)

Since the identification of Hendra virus (HeV) infections in horses in Australia in 1994, more than 80 outbreaks in horses have been reported, and four out of seven spillover infections in humans had a fatal outcome. With the availability of a subuni

Externí odkaz: https://doaj.org/article/fc2f86f4b0f54b4893c46d9adf1356cd

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Akademický článek

Tandem Repeat Insertion in African Swine Fever Virus, Russia, 2012

Autor: Katja V. Goller, Alexander Malogolovkin, Sergey Katorkin, Denis Kolbasov, Ilya Titov, Dirk Höper, Martin Beer, Günther M. Keil, Raquel Portugal, Sandra Blome

Publikováno v: Emerging Infectious Diseases, Vol 21, Iss 4, Pp 731-732 (2015)

Externí odkaz: https://doaj.org/article/b5909c11da58434db0fc3fa6ba2474f4

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Efficient transgene insertion in a pseudorabies virus vector by CRISPR/Cas9 and marker rescue-enforced recombination

Autor: Thomas C. Mettenleiter, Tonny Kabuuka, Alexandra Hübner, Günther M. Keil, Walter Fuchs

Publikováno v: Journal of Virological Methods. 262:38-47

For development of vectored vaccines against porcine pathogens the genome of the pseudorabies virus vaccine strain Bartha (PrV-Ba) was previously cloned as an infectious bacterial artificial chromosome (BAC), containing the bacterial replicon and a r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb617c21d0e6f1f760d0ea4cd9fb20cd
https://doi.org/10.1016/j.jviromet.2018.09.009

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Identification of African swine fever virus-like elements in the soft tick genome provides insights into the virus’ evolution

Autor: Antje Wissgott, Lesley Bell-Sakyi, Leonie Forth, Johannes Krause, Dirk Höper, Sébastien Calvignac-Spencer, Samantha Lycett, Martin Beer, J. H. Forth, Sandra Blome, Günther M. Keil, Helge Kampen

Publikováno v: BMC Biology
BMC Biology, Vol 18, Iss 1, Pp 1-18 (2020)
Forth, J H, Forth, L, Lycett, S, Bell-Sakyi, L, Keil, G, Blome, S, Calvignac-Spencer, S, Wissgott, A, Krause, J, Hoper, D, Kampen, H & Beer, M 2020, ' Identification of African swine fever virus-like elements in the soft tick genome provides insights into the virus’ evolution ', BMC Biology . https://doi.org/10.1186/s12915-020-00865-6

BACKGROUND: African swine fever virus (ASFV) is a most devastating pathogen affecting swine. In 2007, ASFV was introduced into Eastern Europe where it continuously circulates and recently reached Western Europe and Asia, leading to a socio-economic c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7bf2e0481a7c372807a347f4d2a6e0e
http://europepmc.org/articles/PMC7542975

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Molecular and genetic characterization of peste des petits ruminants virus Kurdistan 2011 strain based on the haemagglutinin and fusion protein genes sequences

Autor: Jutta Veits, Günther M. Keil, Nussieba A. Osman

Publikováno v: Small Ruminant Research. 167:82-86

Severe outbreaks of peste des petits ruminants virus (PPRV) occurred during 2011 in wild goats in the Kurdistan region in Iraq. Based on a partial sequence of the nucleoprotein (N) gene the causative virus, named PPRV Kurdistan 2011, was classified a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::032ed9e45e2c78e264894b94e33326ed
https://doi.org/10.1016/j.smallrumres.2018.08.007

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The intracellular proteome of African swine fever virus

Autor: Günther M. Keil, Axel Karger, Catharina Keßler, Jan Hendrik Forth, Thomas C. Mettenleiter, Sandra Blome

Publikováno v: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)

African swine fever (ASF) is a viral disease that affects members of the Suidae family such as African bush pigs, warthogs, but also domestic pigs, and wild boar. It is transmitted by direct contact of naïve with infected animals, by soft ticks of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af7e9d9804e763f22db98444fa132b3
https://doi.org/10.1038/s41598-018-32985-z

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Genetic fusion of peste des petits ruminants virus haemagglutinin and fusion protein domains to the amino terminal subunit of glycoprotein B of bovine herpesvirus 1 interferes with transport and function of gB for BHV-1 infectious replication

Autor: Nussieba A. Osman, Günther M. Keil, Anja Röder, Katrin Giesow

Publikováno v: Virus research. 258

Peste des petits ruminants is an emerging, often fatal viral disease of domestic and wild small ruminants caused by peste des petits ruminants virus. The haemagglutinin and the fusion protein are viral envelope glycoproteins and essential for the inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46da7601e8946605af1fb6e9ddb3655b
https://pubmed.ncbi.nlm.nih.gov/30266631

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Autor: Alexandre Leitão, Chris Upton, Chad Smithson, Carlos Martins, Raquel Portugal, Dirk Höper, Günther M. Keil, João Coelho, Nicole S. Little

Publikováno v: Journal of General Virology. 96:408-419

Two strains of African swine fever virus (ASFV), the high-virulence Lisboa60 (L60) and the low-virulence NH/P68 (NHV), which have previously been used in effective immunization/protection studies, were sequenced. Both were isolated in Portugal during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff63b11a139c40155f97e56c344cdacf
https://doi.org/10.1099/vir.0.070508-0

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Efficient inhibition of African swine fever virus replication by CRISPR/Cas9 targeting of the viral p30 gene (CP204L)

Autor: Walter Fuchs, Günther M. Keil, Bjoern Petersen, Thomas C. Mettenleiter, Alexandra Hübner, Heiner Niemann

Publikováno v: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)

African swine fever is a devastating viral disease of domestic and wild pigs against which no vaccine or therapy is available. Therefore, we applied the CRISPR (clustered regularly interspaced short palindromic repeats) – Cas9 nuclease system to ta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f520c2b515fda9cb6bd83f18d3d6e57f
https://pubmed.ncbi.nlm.nih.gov/29362418

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