Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Günther Kreil"'
Publikováno v:
FEBS Journal. 277:3147-3157
There has been an increasing interest in single amino acid repeats ever since it was shown that these are the cause of a variety of diseases. Although a systematic study of single amino acid repeats is challenging, they have subsequently been implica
Autor:
Günther Kreil
Publikováno v:
Sitzungsberichte und Anzeiger der mathematisch-naturwissenschaftlichen Klasse. 1:SI3-SI11
Autor:
Günther Kreil, Roberta Lattanzi, Elisa Giannini, Lucia Negri, Mariantonella Colucci, Alessio Metere, Donatella Barra, Pietro Melchiorri
Publikováno v:
British Journal of Pharmacology. 137:1147-1154
The small protein Bv8, isolated from amphibian skin, belongs to a novel family of secretory proteins (Bv8-Prokineticin family, SWISS-PROT: Q9PW66) whose orthologues have been conserved throughout evolution, from invertebrates to humans. When injected
Autor:
Günther Kreil, Lucia Negri, Pietro Melchiorri, Giuseppina Mignogna, Christa Mollay, Christian Wechselberger, Donatella Barra
Publikováno v:
European Journal of Pharmacology. 374:189-196
From skin secretions of Bombina variegata and Bombina bombina, we isolated a small protein termed Bv8. The sequence of its 77 amino acids was established by peptide analysis and by cDNA cloning of the Bv8 precursor. Bv8 stimulates the contraction of
Publikováno v:
Journal of Biological Chemistry. 273:22466-22470
Using Expressed Sequence Tags (ESTs) deposited in the data banks, a cDNA has been assembled that encodes a protein related to the hyaluronidases from bee venom and mammalian sperm. Expression of this cDNA yielded a polypeptide termed HYAL2, which is
Publikováno v:
European Journal of Biochemistry. 247:810-814
The cDNA encoding PH-20 hyaluronidase from human sperm has been mutated at five positions by in vitro mutagenesis. We have changed three acidic amino acids and two arginine residues that are conserved in the sequence of mammalian PH-20 polypeptides a
Publikováno v:
European Journal of Biochemistry. 247:107-113
From a Xenopus laevis skin library a cDNA coding for dipeptidyl aminopeptidase IV (DPP IV) was isolated. The ORF codes for a protein with sequence similarity to DPP-IV-like proteins, including mammalian DPP IV and X. laevis fibroblast activation fact
Autor:
Stefano Pascarella, Christian Wechselberger, Donatella Barra, Günther Kreil, C Hinterleitner, Gino Amiconi, Christa Mollay, Giuseppina Mignogna
Publikováno v:
Protein Science. 5:357-362
From skin secretions of the European frog Bombina bombina, a new peptide has been isolated that contains 60 amino acids, including 10 cysteine residues. Its sequence was determined by automated Edman degradation and confirmed by analysis of the cDNA
Autor:
Günther Kreil, Michael Gmachl
Publikováno v:
Journal of Biological Chemistry. 270:12704-12708
From a cDNA library prepared from venom glands of worker bees, clones encoding the precursors of apamin and MCD peptide have been isolated. The cDNAs are similar at the 5'-ends and identical in their 3'-regions. Analysis of the corresponding genes ha
Autor:
Günther Kreil, Michael Gmachl
Publikováno v:
Proceedings of the National Academy of Sciences. 90:3569-3573
The venom of honeybees, Apis mellifera, contains several biologically active peptides and two enzymes, one of which is a hyaluronidase. By using degenerate oligonucleotides derived from the amino-terminal sequence of this hyaluronidase reported by ot