Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Günther Konwalinka"'
Autor:
Reinhard Kofler, Nicole Bacher, Martin Tiefenthaler, Hermann Stuppner, Sonja Sturm, Michael J. Ausserlechner, Günther Konwalinka
Publikováno v:
British Journal of Haematology. 132:615-622
Natural products are still an untapped source of promising lead compounds for the generation of antineoplastic drugs. Here, we investigated for the first time the antiproliferative and apoptotic effects of highly purified oxindole alkaloids, namely i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b61e9c4b4206116d3976eae0dac45b
https://doi.org/10.1111/j.1365-2141.2005.05907.x
https://doi.org/10.1111/j.1365-2141.2005.05907.x
Autor:
Gertrud Haas, Markus Geiger, Wolfgang Göttinger, Manfred Frick, Günther Konwalinka, Monika Ritsch-Marte, Hartwig P. Huemer, Wolfgang Singer, Eveline U. Irschick
Publikováno v:
Ophthalmic Research. 38:164-174
Retinal pigment epithelial (RPE) cells provide crucial functions for the maintenance of the retinal environment. We investigated the phagocytotic mechanisms of RPE cells evaluating the question whether particle uptake underlies a diurnal rhythm. Addi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7490e85c8af9e90863d852d45dcda32
https://doi.org/10.1159/000091476
https://doi.org/10.1159/000091476
Autor:
Karl-Hans Ongania, Nigel B. Perry, R. Schwaha, Christian Zidorn, K. Joehrer, Hermann Stuppner, Richard Greil, Ernst-Peter Ellmerer, Günther Konwalinka
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4a3a1ae3263e353d9df9463f3a5aec
https://doi.org/10.2174/1570178054406002
https://doi.org/10.2174/1570178054406002
Autor:
Hermann Stuppner, Günther Konwalinka, Nadja Schwaiger, Ernst-Peter Ellmerer, Christian Zidorn
Publikováno v:
Tetrahedron Letters. 45:3433-3436
Apart from a number of known sesquiterpenoids, a novel chlorinated sesquiterpene lactone glucoside––13-chloro-3-O-β-d-glucopyranosylsolstitialin––has been isolated from the Southwestern European plant Leontodon palisae (Asteraceae, tribe Lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edcab5d647d139566fb8bc5e977c8bec
https://doi.org/10.1016/j.tetlet.2004.03.006
https://doi.org/10.1016/j.tetlet.2004.03.006
Autor:
Oliver Mühlmann, Günther Konwalinka, Nicole Bacher, Martin Tiefenthaler, Elisabeth M. C. Strasser-Wozak, Florian Hohla, Wolfgang Wein
Publikováno v:
STEM CELLS. 21:266-271
In phase I and II clinical trials, the deoxycytidine analogue 2',2' difluorodeoxycytidine (dFdC, gemcitabine) has shown promising antitumor activity in leukemia as well as in solid tumors. Preclinical and clinical studies of gemcitabine suggested tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc8c99086c0b0aa5150459101b84c30
https://doi.org/10.1634/stemcells.21-3-266
https://doi.org/10.1634/stemcells.21-3-266
Autor:
Wolfgang Wein, Nicole Bacher, Oliver Mühlmann, Günther Konwalinka, Martin Tiefenthaler, EU Irschick, Elisabeth M. C. Strasser-Wozak, Florian Hohla
Publikováno v:
Immunobiology. 207:149-157
The effect of 2',2'-difluorodeoxycytidine (dFdC) on in vitro human lymphocyte response was assessed in comparison with that of its major metabolite 2',2'-difluorodeoxyuridine (dFdU). Peripheral blood mononuclear cells (PBMNC) from healthy human volun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371b3872d8df396a55366294bb94b2f0
https://doi.org/10.1078/0171-2985-00223
https://doi.org/10.1078/0171-2985-00223
Autor:
Martin Tiefenthaler, Bernd L. Hartmann, Nicole Bacher, Raimund Margreiter, Reinhard Kofler, Albert Amberger, Günther Konwalinka
Publikováno v:
British Journal of Haematology. 114:574-580
Acute tumour-lysis syndrome (ATLS) is a frequently fatal complication after cytoreductive leukaemia therapy. Lactic acidosis is associated with ATLS and its extent is correlated with the severity of ATLS. In the course of cytoreductive therapy, apopt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aca3634410f47094ef5bb10aa14e223
https://doi.org/10.1046/j.1365-2141.2001.02988.x
https://doi.org/10.1046/j.1365-2141.2001.02988.x
Publikováno v:
Scandinavian Journal of Rheumatology. 26:376-379
Cladribine (2-chlorodeoxyadenosine, 2-CdA) is a newer purine analog with specific toxicity to lymphocytes. As lymphocytes play a major role in rheumatoid arthritis (RA), we assessed the safety profile of low-dose 2-CdA in patients who were refractory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e96fd570e2ad0e6dc4ad98508ffe342
https://doi.org/10.3109/03009749709065702
https://doi.org/10.3109/03009749709065702
Autor:
Josef Thaler, Kurt Grünewald, Wolfgang Hilbe, Michael A. Fridrik, Heinz Sill, T. Fluckinger, Herwig Niessner, Dietmar Geissler, Christoph Duba, Marianne Bernhart, Klaus Abbrederis, Manfred Stöger, H. L. Seewann, Werner Linkesch, Hubert Hausmaninger, Heinz Ludwig, Ute Apfelbeck, Richard Greil, Günther Konwalinka, Alois Lang, Jörg Pont, Werner Lin, Dietger Niederwieser
Publikováno v:
Leukemia Research. 21:75-80
Small pilot studies of patients with CML have reported on encouraging response rates after treatment with interferon-alpha (IFNalpha) in combination with low-dose cytosine arabinoside (LD ara-C). We therefore initiated a multi-center phase II trial i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6027c2665908351df95acbcfd0cbd70c
https://doi.org/10.1016/s0145-2126(96)00084-7
https://doi.org/10.1016/s0145-2126(96)00084-7
T Cells and Natural Killer Cells after Treatment of Hairy Cell Leukaemia with 2-Chlorodeoxyadenosine
Publikováno v:
Acta Haematologica. 97:180-183
We report that continuous suppression of CD4+ lymphocyte subsets does not necessarily lead to an increased rate of infections more than 6 months after treatment of hairy cell leukemia (HCL) with 2-chlorodeoxyadenosine (cladribine; 2-CdA). In a retros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc7091be28ecc3e637ef91bea9740e9
https://doi.org/10.1159/000203677
https://doi.org/10.1159/000203677