Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Günther Jahreis"'
Autor:
Frank Edlich, Franziska Fimm-Todt, Martin van der Laan, Joachim Lauterwasser, Hugo Falquez-Medina, Katelyn O'Neill, Günther Jahreis, Xu Luo, Aline Oelgeklaus, Kathrin Funk, Ralf M. Zerbes, Annabell Schreiner, Ramona Klesse
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Receptor–ligand interactions on the cell surface or intrinsic stress signals can commit mammalian cells to apoptosis. In this study, we discover how hexokinases confer resistance to receptor-mediated apoptosis through specific inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5236e4916202a28d39dee358d43b6c30
http://europepmc.org/articles/PMC8379972
http://europepmc.org/articles/PMC8379972
Publikováno v:
Chembiochem : a European journal of chemical biology. 19(8)
Finding new road blacks: A peptidic inhibitor of calcineurin (CaN)-mediated nuclear factor of activated T cells (NFAT) dephosphorylation, which is developed through a template-assisted IANUS (Induced orgANisation of strUcture by matrix-assisted toget
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ab76bb3cf5b7eb9745d4ce5e34876f
https://pubmed.ncbi.nlm.nih.gov/29411932
https://pubmed.ncbi.nlm.nih.gov/29411932
Autor:
Andreas Pech, Günther Jahreis, Christoph Parthier, Tobias Aumüller, Milton T. Stubbs, Michael Schöpfel, Ariunkhur Sharkhuukhen, Eva Höss, Frank Bordusa, Sandra Liebscher
Publikováno v:
Angewandte Chemie. 126:3068-3072
Artifizielle Funktionalisierungen von Proteinen stellen sowohl in der angewandten als auch in der Grundlagenforschung ein wichtiges Werkzeug dar und erweisen sich als eine Herausforderung fur Proteinchemiker. Aufgrund ihrer nativen Regio- und Stereos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d34faa2f506e3609a021e474891a73bc
https://doi.org/10.1002/ange.201307736
https://doi.org/10.1002/ange.201307736
Autor:
Miroslav Malesevic, Alexander Rentzsch, Mike Schutkowski, Gunter Fischer, Günther Jahreis, Viktoria Kahlert, Bernhard Schlott
Publikováno v:
bchm. 394:1057-1067
Cyclosporine A (CsA) is a cyclic undecapeptide well known for its ability to prevent rejection episodes after organ transplantation via gain-of-function. Therefore, biomedical studies on CsA have been focused on both immunosuppressive properties and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970be5dff5948bc9481aca3293d1b7c0
https://doi.org/10.1515/hsz-2013-0125
https://doi.org/10.1515/hsz-2013-0125
Publikováno v:
Chemistry - A European Journal. 19:1179-1183
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfcb89c1cbdb374f2e5dee111527aae0
https://doi.org/10.1002/chem.201203721
https://doi.org/10.1002/chem.201203721
Autor:
Hans-Jörg Hofmann, Gunter Fischer, Stefan Berger, Günther Jahreis, Claudia Kunz, Robert Günther
Publikováno v:
Journal of Peptide Science. 18:400-404
The influence of lithium cations on the cis/trans isomerization of prolyl peptide bonds was investigated in a quantitative manner in trifluoroethanol (TFE) and acetonitrile, employing NMR techniques. The focus was on various environmental and structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fdc03c30866818dfb8903c0282c0f08
https://doi.org/10.1002/psc.2410
https://doi.org/10.1002/psc.2410
Autor:
Laurent Debelle, Laurent Duca, Günther Jahreis, Anthony Rusciani, Reinhard H.H. Neubert, Michael C. Jung, Christian E.H. Schmelzer, Anthony S. Weiss, Andrea Heinz
Publikováno v:
Biochimie. 94:192-202
This study aimed to investigate the degradation of the natural substrates tropoelastin and elastin by the neutrophil-derived serine proteases human leukocyte elastase (HLE), proteinase 3 (PR3) and cathepsin G (CG). Focus was placed on determining the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398d9a093be390d47292ae9aaff88952
https://doi.org/10.1016/j.biochi.2011.10.006
https://doi.org/10.1016/j.biochi.2011.10.006
Autor:
Eva Bosse-Doenecke, Rainer Rudolph, Mohanraj Gopalswamy, Jochen Balbach, Nils Drechsler, Günther Jahreis, Julia Fröbel
Publikováno v:
Biophysical Chemistry. 154:66-72
The parathyroid hormone (PTH)1 receptor is a member of the class B G protein-coupled receptor (GPCR) family and regulates bone and mineral metabolism of vertebrates. A truncated highly active parathyroid hormone fragment PTH (1–34) exerts stimulato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68278294a9013b616a4fe7a1bda2135
https://doi.org/10.1016/j.bpc.2011.01.002
https://doi.org/10.1016/j.bpc.2011.01.002
Autor:
Katja Haupt, Chao Yu, Günther Jahreis, Christian Lücke, Cordelia Schiene-Fischer, Markus Liebscher
Publikováno v:
ChemBioChem. 11:1727-1737
The hsp70 chaperone DnaK from E. coli plays a major role in cellular stress response and is involved in assisted protein folding in vivo. By screening a combinatorial peptide library, we identified several DnaK-specific peptide ligands with nanomolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95cbee138852e4e3b4706c4e676016d8
https://doi.org/10.1002/cbic.201000166
https://doi.org/10.1002/cbic.201000166
Autor:
Laurent Duca, Günther Jahreis, Christian Ihling, Christian E.H. Schmelzer, Wolfgang Sippl, Reinhard H.H. Neubert, Anthony Rusciani, Anthony S. Weiss, Andrea Heinz, Samuel Taddese, Michael C. Jung
Publikováno v:
FEBS Journal. 277:1939-1956
To provide a basis for the development of approaches to treat elastin-degrading diseases, the aim of this study was to investigate the degradation of the natural substrate tropoelastin by the elastinolytic matrix metalloproteinases MMP-7, MMP-9, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fa743388889c4243a3950d3b5965a89
https://doi.org/10.1111/j.1742-4658.2010.07616.x
https://doi.org/10.1111/j.1742-4658.2010.07616.x