Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Günther H S, Richter"'
Autor:
Oxana Schmidt, Nadja Nehls, Carolin Prexler, Kristina von Heyking, Tanja Groll, Katharina Pardon, Heathcliff D. Garcia, Tim Hensel, Dennis Gürgen, Anton G. Henssen, Angelika Eggert, Katja Steiger, Stefan Burdach, Günther H. S. Richter
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-16 (2021)
Abstract Background Histone acetylation and deacetylation seem processes involved in the pathogenesis of Ewing sarcoma (EwS). Here histone deacetylases (HDAC) class I were investigated. Methods Their role was determined using different inhibitors inc
Externí odkaz:
https://doaj.org/article/37a514c7436446fcbab46189c911acc5
Autor:
Oxana Schmidt, Nadja Nehls, Carolin Prexler, Kristina von Heyking, Tanja Groll, Katharina Pardon, Heathcliff D. Garcia, Tim Hensel, Dennis Gürgen, Anton G. Henssen, Angelika Eggert, Katja Steiger, Stefan Burdach, Günther H. S. Richter
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-3 (2022)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/e2b35416a024402dba01b1542821c08e
Autor:
Kristina vonHeyking, Julia Calzada‐Wack, Stefanie Göllner, Frauke Neff, Oxana Schmidt, Tim Hensel, David Schirmer, Annette Fasan, Irene Esposito, Carsten Müller‐Tidow, Poul H. Sorensen, Stefan Burdach, Günther H. S. Richter
Publikováno v:
Molecular Oncology, Vol 11, Iss 9, Pp 1288-1301 (2017)
Ewing sarcomas (ES) are highly malignant, osteolytic bone or soft tissue tumors, which are characterized by EWS–ETS translocations and early metastasis to lung and bone. In this study, we investigated the role of the BRICHOS chaperone domain‐cont
Externí odkaz:
https://doaj.org/article/a89b68b466eb4b23a7712fee193d0f90
Autor:
Uwe Thiel, Sebastian J. Schober, Ingo Einspieler, Andreas Kirschner, Melanie Thiede, David Schirmer, Katja Gall, Franziska Blaeschke, Oxana Schmidt, Susanne Jabar, Andreas Ranft, Rebeca Alba Rubío, Uta Dirksen, Thomas G. P. Grunewald, Poul H. Sorensen, Günther H. S. Richter, Irene Teichert von Lüttichau, Dirk H. Busch, Stefan E. G. Burdach
Publikováno v:
OncoImmunology, Vol 6, Iss 5 (2017)
Background: Chondromodulin-I (CHM1) sustains malignancy in Ewing sarcoma (ES). Refractory ES carries a dismal prognosis and patients with bone marrow (BM) metastases do not survive irrespective of therapy. We assessed HLA-A*02:01/CHM1-specific allore
Externí odkaz:
https://doaj.org/article/3cc9a9d7f65440adbaafa92d0d5289d0
Autor:
Andreas Kirschner, Melanie Thiede, Thomas G. P. Grünewald, Rebeca Alba Rubio, Günther H. S. Richter, Thomas Kirchner, Dirk H. Busch, Stefan Burdach, Uwe Thiel
Publikováno v:
OncoImmunology, Vol 6, Iss 2 (2017)
Pregnancy-associated plasma protein-A (PAPPA), also known as pappalysin, is a member of the insulin-like growth factor (IGF) family. PAPPA acts as a protease, cleaving IGF inhibitors, i.e., IGF binding proteins (IGFBPs), thereby setting free IGFs. Th
Externí odkaz:
https://doaj.org/article/d3407d35de154a79b4aacf83f32d4e11
Autor:
Andreas, Kirschner, Melanie, Thiede, Thomas G P, Grünewald, Rebeca, Alba Rubio, Günther H S, Richter, Thomas, Kirchner, Dirk H, Busch, Stefan, Burdach, Uwe, Thiel
Publikováno v:
Oncoimmunology
Pregnancy-associated plasma protein-A (PAPPA), also known as pappalysin, is a member of the insulin-like growth factor (IGF) family. PAPPA acts as a protease, cleaving IGF inhibitors, i.e., IGF binding proteins (IGFBPs), thereby setting free IGFs. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c42e6fccc2b9c0ee026c1ea435dd385
https://pubmed.ncbi.nlm.nih.gov/28344885
https://pubmed.ncbi.nlm.nih.gov/28344885
Pappalysin-1 T cell receptor transgenic allo-restricted T cells kill Ewing sarcomain vitroandin vivo
Autor:
Thomas G. P. Grunewald, Melanie Thiede, Andreas Kirschner, Thomas Kirchner, Uwe Thiel, Stefan Burdach, Dirk H. Busch, Günther H S Richter, Rebeca Alba Rubio
Publikováno v:
OncoImmunology, Vol 6, Iss 2 (2017)
Pregnancy-associated plasma protein-A (PAPPA), also known as pappalysin, is a member of the insulin-like growth factor (IGF) family. PAPPA acts as a protease, cleaving IGF inhibitors, i.e., IGF binding proteins (IGFBPs), thereby setting free IGFs. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f605068d991830521cb41114076c877
https://doi.org/10.1080/2162402x.2016.1273301
https://doi.org/10.1080/2162402x.2016.1273301
Autor:
Thomas G P, Grunewald, Semjon, Willier, Dirk, Janik, Rebekka, Unland, Cora, Reiss, Olivia, Prazeres da Costa, Thorsten, Buch, Uta, Dirksen, Günther H S, Richter, Frauke, Neff, Stefan, Burdach, Elke, Butt
Publikováno v:
Biology of the cell. 105(11)
Ewing's sarcoma (ES) is the second most common bone-associated malignancy in children and is driven by the fusion oncogene EWS/FLI1 and characterised by rapid growth and early metastasis. Here, we explored the role of the Zyxin-related protein thyroi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71a7d615eef79bcc51d445c141392bd6
https://pubmed.ncbi.nlm.nih.gov/24033704
https://pubmed.ncbi.nlm.nih.gov/24033704
Autor:
Isabella V, Miller, Graca, Raposo, Ulrich, Welsch, Olivia, Prazeres da Costa, Uwe, Thiel, Maria, Lebar, Martina, Maurer, Hans-Ulrich, Bender, Irene, von Luettichau, Günther H S, Richter, Stefan, Burdach, Thomas G P, Grunewald
Publikováno v:
Biology of the cell. 105(7)
Exosomes are small RNA- and protein-containing extracellular vesicles (EVs) that are thought to mediate hetero- and homotypic intercellular communication between normal and malignant cells.Tumour-derived exosomes are believed to promote re-programmin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38a3d20f9db3b95bd52ff27d2cefb2ba
https://pubmed.ncbi.nlm.nih.gov/23521563
https://pubmed.ncbi.nlm.nih.gov/23521563
Autor:
Günther H S, Richter, Annette, Fasan, Kristina, Hauer, Thomas G P, Grunewald, Colette, Berns, Sabine, Rössler, Ivonne, Naumann, Martin S, Staege, Simone, Fulda, Irene, Esposito, Stefan, Burdach
Publikováno v:
The Journal of pathology. 230(1)
Metastatic spread in Ewing sarcomas (ES) is frequent and haematogenous. G-protein coupled receptor 64 (GPR64), an orphan receptor with normal expression restricted to human epididymis is specifically over-expressed in ES among sarcoma, but also up-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea67c05ded807b3b3205a53022dc8f04
https://pubmed.ncbi.nlm.nih.gov/23338946
https://pubmed.ncbi.nlm.nih.gov/23338946