Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Günther Gercken"'
Publikováno v:
Analytical Cellular Pathology, Vol 15, Iss 2, Pp 61-72 (1997)
The mineral‐dust induced activation of pulmonary phagocytes is thought to be involved in the induction of severe lung diseases. The activation of bovine alveolar macrophages (BAM) by silica was investigated by flow cytometry. Short‐term incubatio
Externí odkaz:
https://doaj.org/article/f7a2249e22eb4e9993bf57230705b39e
Publikováno v:
Gene Expression Patterns. 3:685-691
Recently, a new member of the presenilin family was identified as an aspartyl protease that cleaves signal peptides within hydrophobic domains, and was, therefore, named signal peptide peptidase (SPP). We isolated cDNAs coding for mouse and human ort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd91965a14f74b069fb172a361c1cb4a
https://doi.org/10.1016/s1567-133x(03)00094-2
https://doi.org/10.1016/s1567-133x(03)00094-2
Autor:
S. Koschyk, O. Holz, G Abel, M. Böttcher, Rudolf A. Jörres, H. Magnussen, P. Timm, Günther Gercken
Publikováno v:
International Archives of Occupational and Environmental Health. 74:242-248
As known from studies in animal and human subjects, ozone can exert effects on the immune response including allergic sensitisation and allergen responsiveness. The objective of the present study was to assess the changes in lymphocyte subsets in bro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2fbad7547a6056e7140676a238b1f0
https://doi.org/10.1007/s004200000216
https://doi.org/10.1007/s004200000216
Publikováno v:
Toxicology Letters. :69-75
The aim of our study was to determine agonist- and time-dependent phosphorylation of distinct proteins in bovine alveolar macrophages after activation with quartz dusts and heavy metal-coated silica particles. Silica particles were coated with vanadi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8dc98d0e2f56bead0c1de8c0d97685
https://doi.org/10.1016/s0378-4274(98)00052-6
https://doi.org/10.1016/s0378-4274(98)00052-6
Publikováno v:
Toxicology Letters. :59-67
Bovine alveolar macrophages (BAM) were labeled with [3H]-choline or [3H]-ethanolamine and exposed to quartz dust, metal oxide-coated silica particles, Escherichia coli-derived lipopolysaccharide (LPS) or tumor promotor 12-O-tetradecanoyl phorbol 13-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d35d0d48c2994baef22ed1fbb83f349
https://doi.org/10.1016/s0378-4274(98)00051-4
https://doi.org/10.1016/s0378-4274(98)00051-4
Publikováno v:
Chemistry and Physics of Lipids. 88:83-96
There is strong evidence that the oxidation of plasma lipoproteins plays an important role in atherogenesis. The exact mechanisms by which lipoprotein oxidation occurs in the presence of other plasma constituents, however, remains unclear. To investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dc798e012675af1a0faca8ed661ca27
https://doi.org/10.1016/s0009-3084(97)00038-8
https://doi.org/10.1016/s0009-3084(97)00038-8
Autor:
M Radloff, Günther Gercken
Publikováno v:
Toxicology Letters. 88:139-145
Bovine alveolar macrophages (BAM) were stimulated with quartz dusts, metal oxide-coated silica particles, and zymosan. To investigate the role of protein kinase C (PKC) in the mechanism of agonist-induced activation 12-O-tetradecanoyl phorbol 13-acet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cdf41133a643f3d67da1d6357ae74bf
https://doi.org/10.1016/0378-4274(96)03729-0
https://doi.org/10.1016/0378-4274(96)03729-0
Publikováno v:
Toxicology Letters. 88:121-129
Bovine alveolar macrophages were exposed in vitro to quartz dusts, metal-containing dusts or silica particles coated with a single metal oxide. The release of reactive oxygen intermediates (RO1) was measured in short-term incubations (90 min). The se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f07e131444a797ab0efbd2ca459fdc2
https://doi.org/10.1016/0378-4274(96)03727-7
https://doi.org/10.1016/0378-4274(96)03727-7
Betaine Generation in Cardiac Myocytes after Adrenergic Activation of Phosphatidylcholine Hydrolysis
Publikováno v:
Journal of Molecular and Cellular Cardiology. 28:1109-1118
In this report, effects of α 1 -adrenergic stimulation on phosphatidylcholine (PC) hydrolysis and the subsequent generation of water-soluble choline metabolites were investigated after preincubation of isolated cardiac myocytes of adult rats with [m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b9ad3e34733b946f5696851b0e1dfa
https://doi.org/10.1006/jmcc.1996.0102
https://doi.org/10.1006/jmcc.1996.0102
Publikováno v:
Journal of Toxicology and Environmental Health. 39:341-354
The release of reactive oxygen intermediates (ROI) from bovine alveolar macrophages (BAM) after stimulation with heavy metal-containing dusts was investigated. BAM were obtained by postmortem lavages of bovine lungs. The dusts were collected from was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0759bd163fa0c03d51dda1ba103d041f
https://doi.org/10.1080/15287399309531756
https://doi.org/10.1080/15287399309531756