Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Günther Bernhardt"'
Autor:
Lukas Grätz, Katharina Tropmann, Merlin Bresinsky, Christoph Müller, Günther Bernhardt, Steffen Pockes
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-3 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/e9afb80c8d6b4c9386fc717c1f34bab8
Autor:
Xueke She, Andrea Pegoli, Judith Mayr, Harald Hübner, Günther Bernhardt, Peter Gmeiner, Max Keller
Publikováno v:
ACS Omega, Vol 2, Iss 10, Pp 6741-6754 (2017)
Externí odkaz:
https://doaj.org/article/ccc71977ac8542fabfefb2480ed6e0de
Autor:
Kilian K. Kuhn, Timo Littmann, Stefanie Dukorn, Miho Tanaka, Max Keller, Takeaki Ozawa, Günther Bernhardt, Armin Buschauer
Publikováno v:
ACS Omega, Vol 2, Iss 7, Pp 3616-3631 (2017)
Externí odkaz:
https://doaj.org/article/56c031c8429644c8b1dea5927f73ff04
Autor:
Lisa Schindler, Jutta Moosbauer, Daniel Schmidt, Thilo Spruss, Lukas Grätz, Steffen Lüdeke, Frank Hofheinz, Sebastian Meister, Bernd Echtenacher, Günther Bernhardt, Jens Pietzsch, Dirk Hellwig, Max Keller
Publikováno v:
Cancers; Volume 14; Issue 19; Pages: 4922
Cancers 14(2022), 4922
Cancers 14(2022), 4922
Overexpression of the neurotensin receptor type 1 (NTS1R), a peptide receptor located at the plasma membrane, has been reported for a variety of malignant tumors. Thus, targeting the NTS1R with 18F- or 68Ga-labeled ligands is considered a straightfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1148c62b0d157cdba630e4f85570ce8e
Autor:
Sabrina Biselli, Mengya Chen, André F. Maia, Armin Buschauer, Timo Littmann, Miho Tanaka, Katharina Tropmann, Maria Gomez-Lazaro, Inês S. Alencastre, Max Keller, Daniela Erdmann, Günther Bernhardt, Takeaki Ozawa, Meriem Lamghari
Publikováno v:
ACS Medicinal Chemistry Letters. 11:1521-1528
Fluorescence labeled ligands have been gaining importance as molecular tools, enabling receptor-ligand-binding studies by various fluorescence-based techniques. Aiming at red-emitting fluorescent ligands for the hH(2)R, a series of squaramides labele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe0863823a5fca7e62802682bda3a936
https://doi.org/10.1021/acsmedchemlett.0c00033
https://doi.org/10.1021/acsmedchemlett.0c00033
Publikováno v:
Journal of Medicinal Chemistry. 63:8198-8215
Within the family of neuropeptide Y (NPY) receptors, the Y4 receptor (Y4R) is unique as it prefers pancreatic polypeptide over NPY and peptide YY. Today, low-molecular-weight Y4R ligands are lacking, in particular antagonists. We synthesized a series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::183178c90b67c0e3e384c5f6012a9865
https://doi.org/10.1021/acs.jmedchem.0c00426
https://doi.org/10.1021/acs.jmedchem.0c00426
Autor:
Ulla Seibel, Günther Bernhardt, David Wifling, Timo Littmann, Edith Bartole, Lukas Grätz, Armin Buschauer
Publikováno v:
Journal of Medicinal Chemistry. 63:5297-5311
Comprehensively characterized fluorescent probes for the histamine H3 receptor (H3R) and especially for the H4R orthologs [e.g., human (h) and mouse (m)] are highly needed as versatile complementar...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2390c7cef4470dee1ff2c510e47fd6f
https://doi.org/10.1021/acs.jmedchem.0c00160
https://doi.org/10.1021/acs.jmedchem.0c00160
Autor:
Mengya Chen, Nicholas D. Holliday, Jianfei Wan, Günther Bernhardt, Max Keller, Corinna G. Gruber, Xueke She, Andrea Pegoli, Harald Hübner, Peter Gmeiner, Jessica Carpenter, David Wifling
Publikováno v:
Journal of Medicinal Chemistry. 63:4133-4154
Fluorescently labeled dibenzodiazepinone-type muscarinic acetylcholine receptor (MR) antagonists, including dimeric ligands, were prepared using red-emitting cyanine dyes. Probes containing a fluorophore with negative charge showed high M2R affinitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2e95ec7277d054214aa57332c1016c5
https://doi.org/10.1021/acs.jmedchem.9b02172
https://doi.org/10.1021/acs.jmedchem.9b02172
Publikováno v:
RSC Medicinal Chemistry. 11:274-282
The recently resolved crystal structure of the neuropeptide Y Y1 receptor (Y1R), co-crystallized with the high-affinity (pKi: 10.11), argininamide-type Y1R antagonist UR-MK299 (2), revealed that the Nω-carbamoyl substituent (van der Waals volume: 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::738dfb1a31afa81cad597e6492983910
https://doi.org/10.1039/c9md00538b
https://doi.org/10.1039/c9md00538b
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0117185 (2015)
In contrast to the corresponding mouse and rat orthologs, the human histamine H4 receptor (hH4R) shows extraordinarily high constitutive activity. In the extracellular loop (ECL), replacement of F169 by V as in the mouse H4R significantly reduced con
Externí odkaz:
https://doaj.org/article/610624632ce14fd8b40726e09588250a