Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Günther, Loidl"'
Publikováno v:
CHIMIA, Vol 67, Iss 12 (2013)
The Swiss fine chemicals company Bachem, pioneer and specialist in the chemical synthesis of peptides, has also become an internationally leading manufacturer of peptide active pharmaceutical ingredients (APIs). In response to increasing demands in s
Externí odkaz:
https://doaj.org/article/4037efbf3fce4127923b4fa5fb2b1e60
Publikováno v:
Journal of Peptide Science. 23:757-762
In solid-phase peptide synthesis, the nominal batch size is calculated using the starting resin substitution and the mass of the starting resin. The starting resin substitution constitutes the basis for the calculation of a whole set of important pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7939220ef5ec3388a9d9ac943ac75d39
https://doi.org/10.1002/psc.3021
https://doi.org/10.1002/psc.3021
Publikováno v:
Journal of Peptide Science
Aspartimide (Asi) formation is a notorious side reaction in peptide synthesis that is well characterized and described in literature. In this context, we observed significant amounts of chain termination in Fmoc-SPPS while synthesizing the N-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a57f19119f9553caf880a0d3dc212b2
https://pubmed.ncbi.nlm.nih.gov/31309675
https://pubmed.ncbi.nlm.nih.gov/31309675
Publikováno v:
Journal of Peptide Science
In solid‐phase peptide synthesis, the nominal batch size is calculated using the starting resin substitution and the mass of the starting resin. The starting resin substitution constitutes the basis for the calculation of a whole set of important p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0816acda8d8b6adc03238d026a11b31
https://pubmed.ncbi.nlm.nih.gov/28635051
https://pubmed.ncbi.nlm.nih.gov/28635051
Autor:
Junya Nagai, Osmo Siikanen, Mikihisa Takano, Juha Apajalahti, Timo Vaara, John E. Fox, Günther Loidl, Niels Frimodt-Møller, Martti Vaara, Frank Hansen
Publikováno v:
Antimicrobial Agents and Chemotherapy. 52:3229-3236
The lack of novel antibiotics against gram-negative bacteria has reinstated polymyxins as the drugs of last resort to treat serious infections caused by extremely multiresistant gram-negative organisms. However, polymyxins are nephrotoxic, and this f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da08f937acdf6652d69472a4ff829253
https://doi.org/10.1128/aac.00405-08
https://doi.org/10.1128/aac.00405-08
Publikováno v:
ChemInform. 45
The Swiss fine chemicals company Bachem, pioneer and specialist in the chemical synthesis of peptides, has also become an internationally leading manufacturer of peptide active pharmaceutical ingredients (APIs). In response to increasing demands in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d9b2b2d3705b884c2d29b58853fb220
https://doi.org/10.1002/chin.201416277
https://doi.org/10.1002/chin.201416277
Publikováno v:
CHIMIA, Vol 67, Iss 12 (2013)
The Swiss fine chemicals company Bachem, pioneer and specialist in the chemical synthesis of peptides, has also become an internationally leading manufacturer of peptide active pharmaceutical ingredients (APIs). In response to increasing demands in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21cc058ceb6e16d29e9e0cd86fadeddf
https://pubmed.ncbi.nlm.nih.gov/24594330
https://pubmed.ncbi.nlm.nih.gov/24594330
Autor:
Daniel Fourmy, Nediljko Budisa, Sandrine Poirot, Günther Loidl, Robert Huber, Hans-Jürgen Musiol, Luis Moroder
Publikováno v:
Journal of Peptide Science. 6:139-144
Acetyl-β-(1-azulenyl)-D,L-alanine has been synthesized in high overall yield by the malonic ester condensation procedure, and the racemate has been enzymatically resolved with acylase I from Aspergillus melleus. The enantiomerically pure L-amino aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08de1fb1f8057f3e42c01cecd3f4059b
https://doi.org/10.1002/(sici)1099-1387(200003)6:3<139::aid-psc240>3.0.co
https://doi.org/10.1002/(sici)1099-1387(200003)6:3<139::aid-psc240>3.0.co
Publikováno v:
Journal of Peptide Science. 6:36-46
Based on the peculiar spatial array of the active sites in the internal chamber of the multicatalytic proteasome, as derived from the X-ray structure of yeast proteasome, homo- and heterobivalent inhibitors were designed and synthesized to exploit th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8bae955b4a93df355906be491ac1f7
https://doi.org/10.1002/(sici)1099-1387(200001)6:1<36::aid-psc232>3.0.co
https://doi.org/10.1002/(sici)1099-1387(200001)6:1<36::aid-psc232>3.0.co
Autor:
Ursula Kreusel, Claudia Fischer, B. Baumgartner, Marianne Hayn, Sharon Page, Monika Haas, Günther Loidl, H. W. Löms Ziegler-Heitbrock, Korbinian Brand, Dieter Neumeier
Publikováno v:
Journal of Biological Chemistry. 274:11611-11618
Extensively oxidized low density lipoprotein (ox-LDL), a modulator of atherogenesis, down-regulates the lipopolysaccharide (LPS)-induced activation of transcription factor NF-kappaB. We investigated whether 4-hydroxynonenal (HNE), a prominent aldehyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e89b8472e087e79ad790da8c71e95dd
https://doi.org/10.1074/jbc.274.17.11611
https://doi.org/10.1074/jbc.274.17.11611