Spliceosome mutations are common in persons with myeloproliferative neoplasm-associated myelofibrosis with RBC-transfusion-dependence and correlate with response to pomalidomide

Autor: Sonja Zweegman, Shanti Natarajan-Amé, Francesco Passamonti, Raajit K. Rampal, Moshe Talpaz, Daobin Zhou, Kelly McCaul, Mary Frances McMullin, Candido E. Rivera, Hiroshi Kawabata, Günther Gastl, H. Joachim Deeg, Heinz Gisslinger, Angela Hamblin, Vincent Ribrag, Reinier Raymakers, John Catalano, P. Mineur, Fabrizio Pane, Giuseppe Saglio, Jean Loup Demory, Josef T. Prchal, Qian Jiang, Kudrat Abdulkadyrov, Emmanuel C. Besa, Richard F. Schlenk, Gary J. Schiller, John T. Reilly, Adam J. Mead, Robert Peter Gale, William Stevenson, Gemma Buck, Kazuma Ohyashiki, Dominique Bordessoule, Mark Drummond, Jianyong Li, Ayalew Tefferi, Ting Liu, Tomoko Hata, Jianhua Zhong, Juan Carlos Hernandez Boluda, Damiano Rondelli, Norio Komatsu, John Mascarenhas, Zhixiang Shen, Timothy Devos, Alessandro M. Vannucchi, Katsuto Takenaka, Randall Brown, Haifa K. Al-Ali, Thomas J. Nevill, Jen Chin Wang, Daniel Tesfa, Jennifer O'Sullivan, Andrew Turner, Guanlin Wang, Galina Salogub, Claire N. Harrison, Dragana Milojkovic, Giovanni Barosi, James W. Vardiman, Peter A. W. te Boekhorst, Ruben A. Mesa, Jan Van Droogenbroeck, Manana Sokolova, Vikas Gupta, Lennart Nilsson, Andrey Zaritskiy, Nikolaos Barkas, Werner Linkesch, Mario Cazzola, Jean-Jacques Kiladjian, Ramon V. Tiu, Kiyoshi Ando, Onima Chowdhury, Emilio Ojeda, Martin Griesshammer, Christian Recher, Alessandro Rambaldi, Francisco Cervantes, Giorgina Specchia

Publikováno v: Leukemia
for the RESUME trialists 2020, ' Spliceosome mutations are common in persons with myeloproliferative neoplasm-associated myelofibrosis with RBC-transfusion-dependence and correlate with response to pomalidomide ', Leukemia . https://doi.org/10.1038/s41375-020-0979-6, https://doi.org/10.1038/s41375-020-0979-6
Chowdhury, O, O’Sullivan, J, Barkas, N, Wang, G, Buck, G, Hamblin, A, Tefferi, A, Al-Ali, H K, Barosi, G, Devos, T, Gisslinger, H, Jiang, Q, Kiladjian, J J, Mesa, R, Passamonti, F, Ribrag, V, Schiller, G, Vannucchi, A M, Zhou, D, McMullin, M F, Zhong, J, Gale, R P, Mead, A J, Catalano, J, Stevenson, W, Gastl, G, Linkesch, W, Van Droogenbroeck, J, Mineur, P, Gupta, V, Turner, A, Nevill, T, Li, J, Shen, Z, Liu, T, Bordessoule, D, Natarajan-Amé, S, Recher, C, Demory, J L, Schlenk, R, Griesshammer, M, Cazzola, M, Saglio, G, Specchia, G, Rambaldi, A, Pane, F, Zweegman, S, te Boekhorst, P, Raymakers, R, Abdulkadyrov, K, Sokolova, M, Salogub, G, Zaritskiy, A, Cervantes, F, Boluda, J C H, Ojeda, E, Tesfa, D, Nilsson, L, Drummond, M, Reilly, J, Harrison, C, Milojkovic, D, Rivera, C, Besa, E, Deeg, H J, Mascarenhas, J, Prchal, J, Tiu, R, Talpaz, M, Wang, J C, Rampal, R, Rondelli, D, McCaul, K, Brown, R, Komatsu, N, Ohyashiki, K, Ando, K, Kawabata, H, Takenaka, K, Hata, T, Vardiman, J & for the RESUME trialists 2021, ' Spliceosome mutations are common in persons with myeloproliferative neoplasm-associated myelofibrosis with RBC-transfusion-dependence and correlate with response to pomalidomide ', Leukemia, vol. 35, no. 4, pp. 1197-1202 . https://doi.org/10.1038/s41375-020-0979-6
Leukemia, 35(4), 1197-1202. Nature Publishing Group

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0edc47d8d0334cb53e4de6e4bb4f5b9f
http://www.scopus.com/inward/record.url?scp=85089142992&partnerID=8YFLogxK

Biological effect of mono- and dinuclear alkylamine platinum(II) compounds on human lymphoma cells

Autor: Kapp, Timo, Magnus, Krueger, Ingo, Ott, Stefanie, Steiner, Petra, Schumacher, David, Nachbaur, Günther, Gastl, Ronald, Gust, Kircher, Brigitte

Publikováno v: In Journal of Inorganic Biochemistry April 2008 102(4):713-720

The prognostic value of additional copies of 1q21 in multiple myeloma depends on the primary genetic event

Autor: Emina Jukic, Johannes Zschocke, Irmgard Verdorfer, Eberhard Gunsilius, Friedrich Fresser, Roman Weger, David Nachbaur, Günther Gastl, Normann Steiner, Dominik Wolf, Michael Steurer, Wolfgang Willenbacher, Ewald Wöll, Markus A. Keller, Carmen Ruepp, Maurus Locher

Publikováno v: American Journal of Hematology

Hyperdiploidy (HRD) and specific immunoglobulin heavy locus (IGH) translocations are primary chromosomal abnormalities (CA) in multiple myeloma (MM). In this retrospective study of 794 MM patients we aimed to investigate clinical features and common

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d945ebf8d0f8de0d5656315b6b690e5d
https://pubmed.ncbi.nlm.nih.gov/32936982

High IDO ‐1 expression in tumor endothelial cells is associated with response to immunotherapy in metastatic renal cell carcinoma

Autor: Andrea Brunner, Andreas Seeber, Wolfgang Horninger, Josef Fritz, Kai-Christian Zimmer, Bettina Zelger, Günther Gastl, Friedrich Aigner, Gerald Klinglmair, Fabian Steinkohl, Renate Pichler

Publikováno v: Cancer Science

Nivolumab belongs to the standard therapy in the second‐line setting of metastatic renal cell carcinoma (mRCC). Although deep and long‐lasting responses are seen in some patients, the majority of patients will further progress. PD‐L1 is still u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ea00f2581806c20faac940d145c5d8
https://doi.org/10.1111/cas.13560

Austrian recommendations for the management of primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis: an expert statement

Autor: Maria Theresa Krauth, Andreas L. Petzer, Sonja Burgstaller, Veronika Buxhofer-Ausch, Stefan Wöhrer, Christine Beham-Schmid, Günther Gastl, Alois Lang, Heinz Gisslinger, Albert Wölfler, Thamer Sliwa, Klaus Geissler, Peter Krippl

Publikováno v: Wiener klinische Wochenschrift. 129:293-302

The entity "myelofibrosis" represents a subgroup of the Philadelphia chromosome-negative myeloproliferative neoplasms. It comprises primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis. This het

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768b2dcccdccc2f2c472044657896471
https://doi.org/10.1007/s00508-016-1120-8