Zobrazeno 1 - 10
of 267
pro vyhledávání: '"Günter Schneider"'
Autor:
Carolin Schneider, Jorina Hilbert, Franziska Genevaux, Stefanie Höfer, Lukas Krauß, Felix Schicktanz, Constanza Tapia Contreras, Shaishavi Jansari, Aristeidis Papargyriou, Thorsten Richter, Abdallah M. Alfayomy, Chiara Falcomatà, Christian Schneeweis, Felix Orben, Ruppert Öllinger, Florian Wegwitz, Angela Boshnakovska, Peter Rehling, Denise Müller, Philipp Ströbel, Volker Ellenrieder, Lena Conradi, Elisabeth Hessmann, Michael Ghadimi, Marian Grade, Matthias Wirth, Katja Steiger, Roland Rad, Bernhard Kuster, Wolfgang Sippl, Maximilian Reichert, Dieter Saur, Günter Schneider
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract Cancer cells must develop strategies to adapt to the dynamically changing stresses caused by intrinsic or extrinsic processes, or therapeutic agents. Metabolic adaptability is crucial to mitigate such challenges. Considering metabolism as a
Externí odkaz:
https://doaj.org/article/74f891ee4bb3409e8f62d1958c65fda1
Autor:
Carolin Schneider, Günter Schneider
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 3, Pp 429-431 (2024)
Therapies targeting pancreatic ductal adenocarcinoma (PDAC), driven in most cases by the KRAS oncogene, continue to present a clinical challenge. This emphasizes the need to explore alternative treatment paradigms in translational research. In this i
Externí odkaz:
https://doaj.org/article/c0d3cbbdea534155a7d35f7d549a6781
Autor:
Johannes Roman Wiessner, Felix Orben, Arlett Schäfer, Lisa Fricke, Günter Schneider, Maximilian Reichert, Alexander Herner, Ulrich Mayr, Veit Phillip, Matthias Treiber, Guido von Figura, Mohamed Abdelhafez, Roland M. Schmid, Christoph Schlag
Publikováno v:
Endoscopy International Open, Vol 12, Iss 03, Pp E361-E366 (2024)
Externí odkaz:
https://doaj.org/article/46a2046c06d74262b70c9e5db2236a92
Autor:
Mariel C. Paul, Christian Schneeweis, Chiara Falcomatà, Chuan Shan, Daniel Rossmeisl, Stella Koutsouli, Christine Klement, Magdalena Zukowska, Sebastian A. Widholz, Moritz Jesinghaus, Konstanze K. Heuermann, Thomas Engleitner, Barbara Seidler, Katia Sleiman, Katja Steiger, Markus Tschurtschenthaler, Benjamin Walter, Sören A. Weidemann, Regina Pietsch, Angelika Schnieke, Roland M. Schmid, Maria S. Robles, Geoffroy Andrieux, Melanie Boerries, Roland Rad, Günter Schneider, Dieter Saur
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
SNAIL promotes tumour metastasis through inducing epithelial to mesenchymal transition (EMT). Here the authors report that SNAIL bypasses senescence and regulates cell cycle progression to promote pancreatic carcinogenesis and this is independent of
Externí odkaz:
https://doaj.org/article/fdf4c0ab459c4aa5ae822ae980ab27e7
Autor:
Claudia Geismann, Charlotte Hauser, Frauke Grohmann, Christian Schneeweis, Nico Bölter, Jan-Paul Gundlach, Günter Schneider, Christoph Röcken, Christian Meinhardt, Heiner Schäfer, Stefan Schreiber, Alexander Arlt
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract The emergence of resistance to systemic therapies in pancreatic ductal adenocarcinoma (PDAC) is still a major obstacle in clinical practice. Both, constitutive and inducible NF-κB activity are known as key players in this context. To identi
Externí odkaz:
https://doaj.org/article/c49d5f0c0be94c26918207d7b67b5744
Autor:
Christian Schneeweis, Zonera Hassan, Katja Ascherl, Matthias Wirth, Stella Koutsouli, Felix Orben, Lukas Krauß, Carolin Schneider, Rupert Öllinger, Oliver H. Krämer, Roland Rad, Maximilian Reichert, Maria S. Robles, Dieter Saur, Günter Schneider
Publikováno v:
Cancer Communications, Vol 42, Iss 4, Pp 360-364 (2022)
Externí odkaz:
https://doaj.org/article/e1fb4121e0174834a41aa53409ac05ce
Publikováno v:
EJNMMI Research, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The incidence and lethality of pancreatic ductal adenocarcinoma (PDAC) will continue to increase in the next decade. For most patients, chemotherapeutic combination therapies remain the standard of care. The development and successful implem
Externí odkaz:
https://doaj.org/article/4112c8cee8034d229192aa4dd81dd3f3
Autor:
Felix Orben, Katharina Lankes, Christian Schneeweis, Zonera Hassan, Hannah Jakubowsky, Lukas Krauß, Fabio Boniolo, Carolin Schneider, Arlett Schäfer, Janine Murr, Christoph Schlag, Bo Kong, Rupert Öllinger, Chengdong Wang, Georg Beyer, Ujjwal M. Mahajan, Yonggan Xue, Julia Mayerle, Roland M. Schmid, Bernhard Kuster, Roland Rad, Christian J. Braun, Matthias Wirth, Maximilian Reichert, Dieter Saur, Günter Schneider
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
Systemic therapies for pancreatic ductal adenocarcinoma (PDAC) remain unsatisfactory. Clinical prognosis is particularly poor for tumor subtypes with activating aberrations in the MYC pathway, creating an urgent need for novel therapeutic targets. To
Externí odkaz:
https://doaj.org/article/eb693ba667cc4d5dae97e9b398a9f104
Autor:
Oliver H. Krämer, Günter Schneider
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 5, Pp n/a-n/a (2022)
Abstract In this commentary on Wang, Wu, Xia, and colleagues, Clinical Translational Medicine, 2022, we sum up and discuss recent evidence on the regulation and relevance of the transcription factor c‐FOS in diffuse large B cell lymphoma cells that
Externí odkaz:
https://doaj.org/article/96c0fc1b619649b2a99a1e4014506df6
Autor:
Katja Peschke, Hannah Jakubowsky, Arlett Schäfer, Carlo Maurer, Sebastian Lange, Felix Orben, Raquel Bernad, Felix N Harder, Matthias Eiber, Rupert Öllinger, Katja Steiger, Melissa Schlitter, Wilko Weichert, Ulrich Mayr, Veit Phillip, Christoph Schlag, Roland M Schmid, Rickmer F Braren, Bo Kong, Ihsan Ekin Demir, Helmut Friess, Roland Rad, Dieter Saur, Günter Schneider, Maximilian Reichert
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 4, Pp n/a-n/a (2022)
Abstract Despite the advance and success of precision oncology in gastrointestinal cancers, the frequency of molecular‐informed therapy decisions in pancreatic ductal adenocarcinoma (PDAC) is currently neglectable. We present a longitudinal precisi
Externí odkaz:
https://doaj.org/article/4db5c456fd664265a4d6c307ca8e323b