Zobrazeno 1 - 10
of 385
pro vyhledávání: '"Günter P, Wagner"'
Autor:
Anasuya Dighe, Jamie Maziarz, Arig Ibrahim-Hashim, Robert A. Gatenby, Kshitiz, Andre Levchenko, Günter P. Wagner
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108593- (2024)
Summary: Gene expression change is a dominant mode of evolution. Mutations, however, can affect gene expression in multiple cell types. Therefore, gene expression evolution in one cell type can lead to similar gene expression changes in another cell
Externí odkaz:
https://doaj.org/article/448ca9ed8de64c84a2076097d1c4a2ff
Autor:
Mihaela Pavličev, Günter P. Wagner
Publikováno v:
MedComm, Vol 3, Iss 4, Pp n/a-n/a (2022)
Abstract In this short paper, we argue that there is a fundamental connection between the medical sciences and evolutionary biology as both are sciences of biological variation. Medicine studies pathological variation among humans (and domestic anima
Externí odkaz:
https://doaj.org/article/a24ebd4942b74eccacde45a7e3a79081
Autor:
Kalle T. Rytkönen, Thomas Faux, Mehrad Mahmoudian, Taija Heinosalo, Mauris C. Nnamani, Antti Perheentupa, Matti Poutanen, Laura L. Elo, Günter P. Wagner
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104235- (2022)
Summary: Trimethylation of histone H3 at lysine 4 (H3K4me3) is a marker of active promoters. Broad H3K4me3 promoter domains have been associated with cell type identity, but H3K4me3 dynamics upon cellular stress have not been well characterized. We a
Externí odkaz:
https://doaj.org/article/9dc03a5660ae47f3baf290543448e530
Publikováno v:
Seminars in Cell & Developmental Biology. 145:3-12
A central topic in research at the intersection of development and evolution is the origin of novel traits. Despite progress on understanding how developmental mechanisms underlie patterns of diversity in the history of life, the problem of novelty c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeea4d55ebb37ef25b4281541d012efb
https://doi.org/10.1016/j.semcdb.2022.03.030
https://doi.org/10.1016/j.semcdb.2022.03.030
Autor:
Thomas A. Stewart, Cong Liang, Justin L. Cotney, James P. Noonan, Thomas J. Sanger, Günter P. Wagner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The homology of digits across amniotes is debated. Here, the authors compare the developmental transcriptomes of digits across five divergent amniotes and show high evolutionary dynamism in expression profiles, with conservation of a distinct develop
Externí odkaz:
https://doaj.org/article/d82a9d859df14949be5f8629056f6fdc
Autor:
Alan C. Love, Günter P. Wagner
Publikováno v:
Evolution & Development. 24:173-176
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b61a613384ca34c46837b10841873102
https://doi.org/10.1111/ede.12420
https://doi.org/10.1111/ede.12420
Autor:
Günter P. Wagner, Mauris C. Nnamani, Arun Rajendra Chavan, Jamie Maziarz, Stella Protopapas, Jennifer Condon, Roberto Romero
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The uterine cervix is the boundary structure between the uterus and the vagina and is key for the maintenance of pregnancy and timing of parturition. Here we report on a comparative transcriptomic study of the cervix of four placental mammal
Externí odkaz:
https://doaj.org/article/c3705a7f926246be8479a8c34ec3cb98
Autor:
Günter P. Wagner
Publikováno v:
Trends in Ecology & Evolution.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::490df0733f281c13823ced376514c699
https://doi.org/10.1016/j.tree.2023.03.009
https://doi.org/10.1016/j.tree.2023.03.009
Publikováno v:
Cells, Vol 10, Iss 5, p 1047 (2021)
Males have evolved species-specifical sperm morphology and swimming patterns to adapt to different fertilization environments. In eutherians, only a small fraction of the sperm overcome the diverse obstacles in the female reproductive tract and succe
Externí odkaz:
https://doaj.org/article/b8c446edb5e048868c44255d4b633d54
Autor:
Mauris C. Nnamani, Soumya Ganguly, Eric M. Erkenbrack, Vincent J. Lynch, Laura S. Mizoue, Yingchun Tong, Heather L. Darling, Monika Fuxreiter, Jens Meiler, Günter P. Wagner
Publikováno v:
Cell Reports, Vol 15, Iss 10, Pp 2097-2108 (2016)
Transcription factors (TFs) play multiple roles in development. Given this multifunctionality, it has been assumed that TFs are evolutionarily highly constrained. Here, we investigate the molecular mechanisms for the origin of a derived functional in
Externí odkaz:
https://doaj.org/article/5f16ba8789c145e3a7460853e1958712