Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Günter Mies"'
Autor:
Konstantin-Alexander Hossmann, Janinne Sylvie Schmid, Günter Mies, Alexander G. Nikonenko, Zhang Ling, Christian Bernreuther, Igor Jakovcevski, Melitta Schachner
Publikováno v:
Brain Structure and Function. 218:1375-1390
Mutations in the X-chromosomal L1CAM gene lead to severe neurological deficits. In this study, we analyzed brains of female mice heterozygous for L1 (L1+/-) to gain insights into the brain structure of human females carrying one mutated L1 allele. Fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111568b399e89d501347a714a0cde14c
https://doi.org/10.1007/s00429-012-0463-9
https://doi.org/10.1007/s00429-012-0463-9
Publikováno v:
Brain Research. 1415:103-108
Oxygen therapy (OT) with hyperbaric oxygen (HBO) or normobaric hyperoxia (NBO) improves the oxygenation of penumbral tissue in experimental ischemic stroke. However, whether this results in the improvement of energy metabolism is unclear. We investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62912e3789aeea8d944db8f8ed12fd6b
https://doi.org/10.1016/j.brainres.2011.07.064
https://doi.org/10.1016/j.brainres.2011.07.064
Autor:
Günter Mies, Bernd Neumaier, Heike Endepols, Heiko Backes, Uwe Himmelreich, Rudolf Graf, Hanna Mertgens
BACKGROUND: Stroke patients suffering from occlusion of the anterior cerebral artery (ACAo) develop cognitive and executive deficits. Experimental models to investigate such functional impairments and recovery are rare and not satisfyingly validated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fded955efa6c1470e6073c1f644fa4ec
https://lirias.kuleuven.be/handle/123456789/478835
https://lirias.kuleuven.be/handle/123456789/478835
Autor:
Ivo Buschmann, Günter Mies, Edda Schneeloch, Hans-Jörg Busch, Christoph Bode, Konstantin-Alexander Hossmann
Publikováno v:
Der Nervenarzt. 77:215-220
Stroke is the leading cause of disability and a major cause of death in Germany and the western world. Ischemic stroke involves different pathophysiologic mechanisms such as thromboembolic vascular occlusion, cerebral micro- or macroangiopathy, extra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38c615bea0b49efe8742c972f4fbbd17
https://doi.org/10.1007/s00115-005-1988-4
https://doi.org/10.1007/s00115-005-1988-4
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 26:927-936
This study sought to establish the photothrombotic ‘ring’ stroke model with late spontaneous reperfusion in adult mice. By applying a 3.0-mm diameter laser ring-beam (514 nm, 0.21 mm thick, 0.65 W/cm2) onto the exposed skull for 60 secs with conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e2fb945fe72bba3daabe29d57b73a6
https://doi.org/10.1038/sj.jcbfm.9600245
https://doi.org/10.1038/sj.jcbfm.9600245
Publikováno v:
Neuroscience Letters. 368:37-40
Preconditioning is a process where a preceding non-lethal form of stress activates a stress response that protects cells against an otherwise lethal form of stress. Preconditioning can be induced in various ways including short-term ischemia or sprea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654369ea2399260de2aaa0ba87ef2e0a
https://doi.org/10.1016/j.neulet.2004.06.061
https://doi.org/10.1016/j.neulet.2004.06.061
Publikováno v:
Proceedings of the National Academy of Sciences. 101:12730-12735
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a powerful arteriogenic factor in the hypoperfused rat brain. To test the pathophysiological relevance of this response, the influence of GM-CSF on brain energy state was investigated in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702e0d5035986ee754d65d8668185f9b
https://doi.org/10.1073/pnas.0404880101
https://doi.org/10.1073/pnas.0404880101
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 24:789-797
A novel photothrombotic ring stroke model was characterized by multiparametric magnetic resonance imaging, imaging of cerebral blood flow (CBF), adenosine triphosphate (ATP), pH, and histology. Ischemia was initiated by transosseous irradiation of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7156b314e27bf0899a86af91fd7ca3b1
https://doi.org/10.1097/01.wcb.0000123905.17746.db
https://doi.org/10.1097/01.wcb.0000123905.17746.db
Publikováno v:
Neuroscience. 123:371-379
The expression of c-jun, mitogen-activated protein kinase phosphatase-1 (mkp-1), caspase-3 and glial fibrillary acidic protein (gfap) was examined at 1, 3 and 7 days after cortical cold injury in rats by in situ hybridisation and immunocytochemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a935861b1300f47ab0ae10b6f9ec98f
https://doi.org/10.1016/j.neuroscience.2003.09.032
https://doi.org/10.1016/j.neuroscience.2003.09.032
Autor:
Christoph Bode, Konstantin-Alexander Hossmann, Hans-Jörg Busch, Ivo R. Buschmann, Günter Mies
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 23:621-628
Experimental and clinical studies have provided evidence for spontaneous and therapeutically induced arteriogenesis after occlusion of major peripheral or cardiac vessels. Such evidence is lacking for the cerebrovascular system. In halothane-anesthet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dfc6dc869fe7020763c18485d8fe81e
https://doi.org/10.1097/01.wcb.0000057741.00152.e4
https://doi.org/10.1097/01.wcb.0000057741.00152.e4