Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Günter Glassmeier"'
Autor:
Christiane K. Bauer, Iris Wulfsen, Udo Schumacher, Günter Glassmeier, Kathrin Hempel, Jürgen R. Schwarz
Publikováno v:
Pflugers Archiv
HERG (human ether-à-go-go-related gene) K(+) currents fulfill important ionic functions in cardiac and other excitable cells. In addition, HERG channels influence cell growth and migration in various types of tumor cells. The mechanisms underlying t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3c611dddcdeea0bc795c32bc3f61c6
https://doi.org/10.1007/s00424-011-1045-z
https://doi.org/10.1007/s00424-011-1045-z
Publikováno v:
Molecular Pharmacology. 80:930-942
Two different mechanisms leading to increased current have been described for the small-molecule human ether-à-go-go-related gene (herg) activator NS1643 [1,3-bis-(2-hydroxy-5-trifluoromethylphenyl)-urea]. On herg1a channels expressed in Xenopus lae
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::716ddbba94f1e8ec32c3707ec59804b5
https://doi.org/10.1124/mol.111.071621
https://doi.org/10.1124/mol.111.071621
Autor:
Angelika Harneit, Jürgen R. Schwarz, Ralf Fliegert, Kerstin Cornils, Frederike Schmid, Selda Genisyuerek, Günter Glassmeier, Andreas H. Guse
Publikováno v:
FEBS Journal. 274:704-713
TRPM4b is a Ca2+-activated, voltage-dependent monovalent cation channel that has been shown to act as a negative regulator of Ca2+ entry and to be involved in the generation of oscillations of Ca2+ influx in Jurkat T-lymphocytes. Transient overexpres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10ce48f2c2e4a38c63176b192e1b5216
https://doi.org/10.1111/j.1742-4658.2006.05614.x
https://doi.org/10.1111/j.1742-4658.2006.05614.x
Autor:
Atanas Ignatov, Mathias Gelderblom, H. Chica Schaller, Ryosuke Takahashi, Jens Urny, Inga Franke, Meriem Rezgaoui, Yuzuru Imai, Ute Süsens, Günter Glassmeier
Publikováno v:
Journal of Cell Science. 119:542-549
The neuropeptide head activator (HA) is a mitogen for mammalian cell lines of neuronal or neuroendocrine origin. HA signalling is mediated by a G-protein-coupled receptor (GPCR). Orphan GPCRs with homology to peptide receptors were screened for HA in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d5bc11bb0146f7cbfe682f6efb74a5
https://doi.org/10.1242/jcs.02766
https://doi.org/10.1242/jcs.02766
Autor:
Günter Glassmeier, Iris Wulfsen, R. Schäfer, J. Flitsch, Jürgen R. Schwarz, Sönke Wimmers, Christiane K. Bauer, D. K. LüDECKE
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 445:589-600
To investigate the presence and possible function of ether-à-go-go-related gene (erg) K(+) channels in human lactotroph cells (HERG channels), primary cultures were prepared from human prolactinoma tissue. In almost all primary cultures, HERG curren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d9cdd9f56f33b8a7f979e17b8c5141
https://doi.org/10.1007/s00424-002-0980-0
https://doi.org/10.1007/s00424-002-0980-0
Autor:
Wolfgang Hampe, Itaru Kojima, Günter Glassmeier, I.Björn Riedel, Katrin Boels, Doris Herrmann, H. Chica Schaller, Jürgen R. Schwarz
Publikováno v:
Journal of Cell Science. 114:3599-3606
The neuropeptide head activator stimulates cell proliferation of neuronal precursor and neuroendocrine cells. The mitogenic signaling cascade requires Ca2+ influx for which, as we show in this paper, the growth-factor-regulated Ca2+-permeable cation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8edb11af4a628b3c3a66c77d8e99ce7f
https://doi.org/10.1242/jcs.114.20.3599
https://doi.org/10.1242/jcs.114.20.3599
Autor:
Hans Scherübl, Ernst-Otto Riecken, Heinz-Johannes Buhr, Michael Höpfner, Bertram Wiedenmann, Christoph Rancso, Günter Glassmeier, S. Niedrig, Hubert J. Stein, Hans-Jürgen Quabbe
Publikováno v:
Annals of the New York Academy of Sciences. 859:241-248
Pancreatic islets contain and release high concentrations of GABA. GABA is thought to play a paracrine role in beta-cells. Searching for a paracrine function of GABA in neoplastic beta-cells we performed patch-clamp studies in isolated human insulino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe73b8d5513fe87db94ab20563bbe94
https://doi.org/10.1111/j.1749-6632.1998.tb11138.x
https://doi.org/10.1111/j.1749-6632.1998.tb11138.x
Publikováno v:
The Journal of Physiology. 510:805-814
1. Gastrointestinal neuroendocrine (NE) cells synthesize, store and secrete gamma-aminobutyric acid (GABA). Recently, an autocrine-paracrine function of GABA has been proposed for secretion from NE cells. 2. To search for functional GABAA receptors i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0b1fe3f6f440ecf3b4edf61354c095
https://doi.org/10.1111/j.1469-7793.1998.805bj.x
https://doi.org/10.1111/j.1469-7793.1998.805bj.x
Autor:
Wiebke Wilkars, Günter Glassmeier, Lucas Graser, Nicola Brandt, Gabriele M. Rune, Danuta Dudzinski, Jürgen R. Schwarz, Martha Lewerenz, Ricardo Vierk, Lars Fester, Simon Gloger, Lepu Zhou, Roland A. Bender
Inhibitors of aromatase, the final enzyme of estradiol synthesis, are suspected of inducing memory deficits in women. In previous experiments, we found hippocampal spine synapse loss in female mice that had been treated with letrozole, a potent aroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f42cba9d515b31a628ee8bc6eef0ea
https://europepmc.org/articles/PMC6703647/
https://europepmc.org/articles/PMC6703647/
Autor:
Jürgen R. Schwarz, Heike Gustke, Udo Schumacher, Tobias Lange, Annika Lange, Günter Glassmeier, Uwe Zangemeister-Wittke, Markus Heine
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 74(2)
Background Small cell lung cancer (SCLC) is one of the most aggressive malignancies implying a very poor prognosis for patients even under therapy. Since it is known that SCLC cells exhibit neurone-like characteristics, we investigated whether a neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d0686640f0577d62890067524940d1
https://pubmed.ncbi.nlm.nih.gov/21511354
https://pubmed.ncbi.nlm.nih.gov/21511354