Interferon-β Modulates the Innate Immune Response against Glioblastoma Initiating Cells.

Autor: Fabian Wolpert, Caroline Happold, Guido Reifenberger, Ana-Maria Florea, René Deenen, Patrick Roth, Marian Christoph Neidert, Katrin Lamszus, Manfred Westphal, Michael Weller, Günter Eisele

Publikováno v: PLoS ONE, Vol 10, Iss 10, p e0139603 (2015)

Immunotherapy targeting glioblastoma initiating cells (GIC) is considered a promising strategy. However, GIC are prone to evade immune response and there is a need for potent adjuvants. IFN-β might enhance the immune response and here we define its

Externí odkaz: https://doaj.org/article/53e824d657814141a7cb2206d37e9ad3

Data from SC68896, a Novel Small Molecule Proteasome Inhibitor, Exerts Antiglioma Activity In vitro and In vivo

Autor: Friederike Schmidt, Michael Weller, Johann Leban, Günter Eisele, Caroline Herrmann, Maria Kissel, Patrick Roth

Purpose: Glioblastomas are among the most lethal neoplasms, with a median survival of Experimental Design: Different tumor cell lines were tested by crystal violet staining for sensitivity to SC68896, given alone or in combination with death ligands.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051f70e6337bc9a3686825ba225d8043
https://doi.org/10.1158/1078-0432.c.6517885

Complementary and alternative medicine use by glioma patients in Switzerland

Autor: Oliver Heese, Günter Eisele, Manfred Westphal, Michael Weller, Caroline Hertler, Katrin Conen, Fabienne Huber, Silvia Hofer, Ulrich Roelcke, Patrick Roth, Tobias Weiss

Publikováno v: Neurooncol Pract

Background During the course of disease, most glioma patients learn that there is no cure for their tumor. It is therefore not uncommon for patients or caregivers to seek complementary and alternative medicine (CAM) treatments. Patterns of CAM use va

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c316638631f2ed8bacf78e4c92e300f2
https://pubmed.ncbi.nlm.nih.gov/31386047

The natural HLA ligandome of glioblastoma stem-like cells: antigen discovery for T cell-based immunotherapy

Autor: Marian Christoph Neidert, Patrick Roth, Luca Regli, Konstantina Kapolou, Janet Kerstin Peper, Manfred Westphal, Stefan Stevanovic, Ana Marcu, Fabian Wolpert, Günter Eisele, Daniel J. Kowalewski, Michael Weller, Reinhard Henschler, Sophie S. Wang, Hans-Georg Rammensee, Lena Katharina Freudenmann, Juliane S. Walz, Manuela Silginer, Katrin Lamszus, Linus Backert

Publikováno v: Acta neuropathologica. 135(6)

Glioblastoma is the most frequent malignant primary brain tumor. In a hierarchical tumor model, glioblastoma stem-like cells (GSC) play a major role in tumor initiation and maintenance as well as in therapy resistance and recurrence. Thus, targeting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60aa10444deb827acd1c8fdd876782b
https://pubmed.ncbi.nlm.nih.gov/29557506

Contents Vol. 60, 2014

Autor: Hesham Elhalawani, Massoud Houshmand, Evandro Leite de Souza, Christopher N. Parris, Ao Liu, Eiji Sunami, Toshiaki Tanaka, Hu Zhu, Fatemeh Ahmadipour, Hiroaki Nozawa, Robin I. Taleb, Adriano Zangrandi, Yusuke Shinoda, Helena Tainá D. Silva, Satz Mengensatzproduktion, Alexander Tuan Falk, Yuejun Liu, Wanlong Zhou, Takeshi Nishikawa, Aline Guillot, Depei Wu, Rami Archid, Inmaculada Alés-Díaz, Eleni Nioti, Ioannis Starakis, Patrizia Mordenti, Michaela Tonder, Jürgen Weinreich, Patrizia Farina, Takeshi Hisada, Anastasia Kostaki, Anita Nasrallah, Noriaki Sunaga, Nicolas Magné, Elpis Mantadakis, Anita Hack, Suellen Maria P. Menezes-Silva, Isis Caroline da Silva Cirino, Masanobu Yamada, Costantine F. Daher, Hironori Yamaguchi, Patrick Roth, Perla Zgheib, Masahiko Motegi, Junichiro Tanaka, Hideomi Yamashita, Sofia Maraki, Michael Weller, Kyoichi Kaira, Vittorina Zagonel, Druckerei Stückle, Alfred Königsrainer, Luigi Cavanna, Behnam Kamalidehghan, Akira Honda, Yaoyao Shen, Hirotaka Kawano, Olivier Collard, Cécile Pacaut, Omar Abdel-Rahman, Toshiaki Watanabe, Hisao Imai, Shinsuke Kazama, Guillaume Moriceau, Kazushige Kawai, José P. Siqueira-Júnior, Giuseppe Lombardi, Shiwei Sun, Mineo Kurokawa, Elena Orlandi, Goh Yong Meng, Jane-Chloé Trone, Günter Eisele, Piers N. Plowman, Ana Maria Galeote-Miguel, Jia Chen, Khaled Bajaeifer, Alessandra Ferro, Tomomichi Kiyomatsu, George Samonis, Angelos Koutras, Ichiro Naruse, Hui Li, Mirvat El-Sibai, Sheba Adam-Zahir, Takashi Toya, Benoite Méry, Joji Kitayama, Tetsuo Ushiku, Yasunori Kogure, Keisuke Hata, Fable Zustovich, Yasuhito Nannya, Gema Durán-Ogalla, Mohamad Mroueh, Soichiro Ishihara, Manuel Benavides-Orgaz, Luis Enrique Rodelo-Haad, Akihide Yoshimi, Minas Sakellakis, Fariha Sharif, Reyhaneh Shakibi, Takayuki Asao, Haruki Kume, Timm C. Schott, Maria José Bermejo-Pérez, Emma C. Bourton

Publikováno v: Chemotherapy. 60:I-IV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::225e9b6b5f2e62f7bf4ce3d5de29ebe8
https://doi.org/10.1159/000440657