Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Günter A. Böhm"'
2
Analysis of eryBI, eryBIII and eryBVII from the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea
Autor: Peter F. Leadlay, Namrita Dhillon, Jesus Cortes, Sabine Gaisser, M.-C. Raynal, Günter A. Böhm, Michel Doumith
Publikováno v: Molecular and General Genetics MGG. 258:78-88
The gene cluster (ery) governing the biosynthesis of the macrolide antibiotic erythromycin A by Saccharopolyspora erythraea contains, in addition to the eryA genes encoding the polyketide synthase, two regions containing genes for later steps in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e0d482665ffb52b4d5e967d837bff7
https://doi.org/10.1007/s004380050709
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3
Mutational Biosynthesis of Novel Rapamycins by a Strain of Streptomyces hygroscopicus NRRL 5491 Disrupted in rapL , Encoding a Putative Lysine Cyclodeaminase
Autor: James Staunton, Peter F. Leadlay, Lake Ee Khaw, Su M. Metcalfe, Günter A. Böhm
Publikováno v: Journal of Bacteriology. 180:809-814
The gene rapL lies within the region of the Streptomyces hygroscopicus chromosome which contains the biosynthetic gene cluster for the immunosuppressant rapamycin. Introduction of a frameshift mutation into rapL by ΦC31 phage-mediated gene replaceme
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe687a6698e5bd94a373d9db6bd2388
https://doi.org/10.1128/jb.180.4.809-814.1998
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4
Analysis of seven genes from the eryAI –eryK region of the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea
Autor: Sabine Gaisser, Günter A. Böhm, Jesus Cortes, Peter F. Leadlay
Publikováno v: Molecular and General Genetics MGG. 256:239-251
The gene cluster (ery) governing the biosynthesis of the macrolide antibiotic erythromycin A by Saccharopolyspora erythraea contains, in addition to the eryA genes encoding the polyketide synthase, two regions containing genes for later steps in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20ef0baf44895ba1fad3efdf5dac2d9
https://doi.org/10.1007/s004380050566
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9
The pipecolate-incorporating enzyme for the biosynthesis of the immunosuppressant rapamycin--nucleotide sequence analysis, disruption and heterologous expression of rapP from Streptomyces hygroscopicus
Autor: Ariane König, James Staunton, Peter F. Leadlay, Philip A. S. Lowden, Torsten Schwecke, Istvin Molnár, Günter A. Böhm
Publikováno v: König, A, Schwecke, T, Molnár, I, Böhm, G A, Lowden, P A S, Staunton, J & Leadlay, P F 1997, ' The pipecolate-incorporating enzyme for the biosynthesis of the immunosuppressant rapamycin-Nucleotide sequence analysis, disruption and heterologous expression of rapP from Streptomyces hygroscopicus ', European Journal of Biochemistry, vol. 247, no. 2, pp. 526-534 . https://doi.org/10.1111/j.1432-1033.1997.00526.x
An open reading frame (rapP) encoding the putative pipecolate-incorporating enzyme (PIE) has been identified in the gene cluster for the biosynthesis of rapamycin in Streptomyces hygroscopicus. Conserved amino acid sequence motifs for ATP binding, AT
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8122ea78480a05e0275aa15c86d91b0d
https://pubmed.ncbi.nlm.nih.gov/9266694
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10
Akademický článek
New Rapamycin Derivatives by Precursor-Directed Biosynthesis.
Autor: Philip A. S. Lowden, Günter A. Böhm, Su Metcalfe, James Staunton, Peter F. Leadlay
Publikováno v: ChemBioChem; Apr2004, Vol. 5 Issue 4, p535-538, 4p
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