Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Günter, Daum"'
Dynamics of Vascular Protective and Immune Supportive Sphingosine-1-Phosphate During Cardiac Surgery
Autor:
Gillis Greiwe, Eileen Moritz, Katharina Amschler, Annika Poppe, Harun Sarwari, Axel Nierhaus, Stefan Kluge, Hermann Reichenspurner, Christian Zoellner, Edzard Schwedhelm, Günter Daum, Björn Tampe, Martin Sebastian Winkler
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IntroductionSphingosine-1-phosphate (S1P) is a signaling lipid and crucial in vascular protection and immune response. S1P mediated processes involve regulation of the endothelial barrier, blood pressure and S1P is the only known inducer of lymphocyt
Externí odkaz:
https://doaj.org/article/e93cb9c6528446ceae82c141b25b9944
Autor:
Martin Sebastian Winkler, Konstantin B. Märtz, Axel Nierhaus, Günter Daum, Edzard Schwedhelm, Stefan Kluge, Markus H. Gräler
Publikováno v:
Journal of Intensive Care, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract Background Sphingosine 1-phosphate (S1P) is a signaling lipid essential in regulating processes involved in sepsis pathophysiology, including endothelial permeability and vascular tone. Serum S1P is progressively reduced in sepsis patients w
Externí odkaz:
https://doaj.org/article/2a21cb14034a4a929eafed89995ed490
Autor:
Eileen Moritz, Danilo Wegner, Stefan Groß, Martin Bahls, Marcus Dörr, Stephan B. Felix, Till Ittermann, Stefan Oswald, Matthias Nauck, Nele Friedrich, Rainer H. Böger, Günter Daum, Edzard Schwedhelm, Bernhard H. Rauch
Publikováno v:
Data in Brief, Vol 12, Iss C, Pp 46-50 (2017)
In this data article, we provide subgroup specific baseline characteristics and serum sphingosine-1-phosphate (S1P) concentrations for healthy individuals within the Study of Health in Pomerania (SHIP)-TREND cohort. After exclusion of subjects with c
Externí odkaz:
https://doaj.org/article/54d364ca57924a71b9a376ec8d515e7c
Autor:
Günter Daum, Martin Winkler, Eileen Moritz, Tina Müller, Maria Geffken, Mirjam von Lucadou, Munif Haddad, Sven Peine, Rainer H. Böger, Axel Larena-Avellaneda, Eike Sebastian Debus, Markus Gräler, Edzard Schwedhelm
Publikováno v:
TH Open, Vol 04, Iss 01, Pp e12-e19 (2020)
Introduction To correctly interpret plasma- or serum-sphingosine-1-phosphate (S1P) concentrations measured in clinical studies it is critical to understand all major determinants in healthy controls. Methods Serum- and plasma-S1P from 174 healthy blo
Externí odkaz:
https://doaj.org/article/46ffbde37986472081d535fcb3c1192d
Autor:
Gunther Marsche, Jelena Kornej, Tina Fischer-Schaepmann, Petra Büttner, Edzard Schwedhelm, Danilo Obradovic, Günter Daum, Erik Holzwirth, Mirjam von Lucadou, Gerhard Hindricks, Markus Trieb, Holger Thiele
Publikováno v:
Heart and Vessels
High-density lipoprotein (HDL), best known for cholesterol transport, also has anti-inflammatory effects. Previous studies suggest involvement of myeloperoxidase (MPO) in modification of HDL. HDL bound Sphingosine-1-phosphate (S1P) has been implied t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec378ae7bbcb6333863b81ac4ec4a415
https://doi.org/10.1007/s00380-021-01908-w
https://doi.org/10.1007/s00380-021-01908-w
Autor:
Rainer H. Böger, Chi-Un Choe, Mirjam von Lucadou, Kristina Marmann, Sven Peine, Edzard Schwedhelm, Catrin Englisch, Susanne Lezius, Günter Daum, Louisa Niemann, Christian Gerloff
Publikováno v:
Movement disorders : official journal of the Movement Disorder SocietyReferences. 36(9)
Background Treatment with sphingosine-1-phosphate (S1P) agonists confers neuroprotective effects in animal models of Parkinson's disease (PD). Objectives We assessed the association of serum S1P levels with motor and cognitive symptoms in patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625331a5187f2c5812160e2cf86539a2
https://pubmed.ncbi.nlm.nih.gov/34083767
https://pubmed.ncbi.nlm.nih.gov/34083767
Autor:
Eileen, Moritz, Gabriele, Jedlitschky, Josefine, Negnal, Mladen V, Tzvetkov, Günter, Daum, Marcus, Dörr, Stephan B, Felix, Henry, Völzke, Matthias, Nauck, Edzard, Schwedhelm, Peter, Meisel, Thomas, Kocher, Bernhard H, Rauch, Birte, Holtfreter
Publikováno v:
Journal of Inflammation Research
Purpose Periodontitis is an inflammatory disease of the oral cavity with an alarmingly high prevalence within the adult population. The signaling lipid sphingosine-1-phosphate (S1P) plays a crucial role in inflammatory and immunomodulatory responses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99b0cd4ca81d811cc6f20eb042bf7ee8
https://pubmed.ncbi.nlm.nih.gov/34234513
https://pubmed.ncbi.nlm.nih.gov/34234513
Autor:
Christian Gerloff, Stefan Blankenberg, Robert Schulz, Susanne Lezius, Tanja Zeller, Günter Daum, Chi-Un Choe, Carsten Buhmann, Edzard Schwedhelm, Monika Pötter-Nerger, Bastian Cheng, Elina Petersen
Publikováno v:
Parkinsonismrelated disorders. 85
Objectives In prospective cohort studies different blood lipid fractions have been identified as risk factors of Parkinson's disease (PD). However, data relating lipoproteins to disease phenotypes and progression in advanced PD patients are sparse. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36ca4a227bc1fee3aca9f137c066092
https://pubmed.ncbi.nlm.nih.gov/33636481
https://pubmed.ncbi.nlm.nih.gov/33636481
Autor:
Bodo Levkau, Lisa Dannenberg, Günter Daum, Markus H. Gräler, Amin Polzin, Gerd Heusch, Klaus Kaiser, Petra Keul
Publikováno v:
The FASEB Journal. 33:1482-1495
Dysfunctional HDL is associated with coronary artery disease (CAD), but its effect on inflammation in vascular smooth muscle cells (VSMCs) in atherosclerosis is unknown. We investigated the effect of healthy human HDL and CAD-HDL on TNF-α-driven inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8b55ecc9c65c262e32d816d12a9475
https://doi.org/10.1096/fj.201801245r
https://doi.org/10.1096/fj.201801245r
Autor:
Matthias Nauck, Stefan Groß, Stephan B. Felix, Bernhard H. Rauch, Stefan Oswald, Nele Friedrich, Martin Bahls, Eileen Moritz, Günter Daum, Rainer H. Böger, Marcus Dörr, Edzard Schwedhelm, Till Ittermann, Danilo Wegner
Publikováno v:
Data in Brief, Vol 12, Iss C, Pp 46-50 (2017)
Data in Brief
Data in Brief
In this data article, we provide subgroup specific baseline characteristics and serum sphingosine-1-phosphate (S1P) concentrations for healthy individuals within the Study of Health in Pomerania (SHIP)-TREND cohort. After exclusion of subjects with c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34aa15aed55edfd519704e8a723db4cf
http://www.sciencedirect.com/science/article/pii/S2352340917300951
http://www.sciencedirect.com/science/article/pii/S2352340917300951