Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Güldal Kirkali"'
Autor:
Güldal Kirkali, Pawel Jaruga, Prasad T Reddy, Alessandro Tona, Bryant C Nelson, Mengxia Li, David M Wilson, Miral Dizdaroglu
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69894 (2013)
Unless repaired, DNA damage can drive mutagenesis or cell death. DNA repair proteins may therefore be used as biomarkers in disease etiology or therapeutic response prediction. Thus, the accurate determination of DNA repair protein expression and gen
Externí odkaz:
https://doaj.org/article/e8f020e1892441c6b2eabec8d7adbdb1
Autor:
Yasar Zorlu, Ufuk Şener, Bedile Irem Tiftikcioglu, Güldal Kirkali, Gamze Tuna, Uğur Kulu, Mustafa Çetiner
Publikováno v:
Noro Psikiyatri Arsivi. 54:57-61
Introduction Relapses of multiple sclerosis (MS) are usually treated with high-dose intravenous methylprednisolone (IVMP), given over 3-10 days. There is no consensus on the optimal duration of treatment. In this study, we aimed to investigate whethe
Autor:
Gamze Tuna, Gunes Can, Melis Kant, Miral Dizdaroglu, Zeliha Tunca, Güldal Kirkali, Ayşegül Özerdem, Deniz Ceylan, Hidayet Ece Arat
Publikováno v:
DNA Repair (Amst)
Oxidatively-induced DNA damage has previously been associated with bipolar disorder. More recently, impairments in DNA repair mechanisms have also been reported. We aimed to investigate oxidatively-induced DNA lesions and expression of DNA glycosylas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc7a523affcca2d74ef5b1f8d634614
https://avesis.deu.edu.tr/publication/details/07125b86-cf63-4f1f-bcd7-69819f201309/oai
https://avesis.deu.edu.tr/publication/details/07125b86-cf63-4f1f-bcd7-69819f201309/oai
Autor:
Yaşar Zorlu, Irem Fatma Uludag, Feriha Ozkaya, Bedile Irem Tiftikcioglu, Güldal Kirkali, Tarik Duksal
Publikováno v:
Seizure. 26:22-25
© 2015 British Epilepsy Association.Purpose There is now extensive evidence to support the involvement of inflammation in the course of epileptic seizures. Seizure-induced changes in serum IL-1β, IL-6 and IL-1Ra levels are reported in several studi
Publikováno v:
Turkish Journal of Biochemistry. 38:118-125
In this review, we aimed to evaluate PhD graduates of the period between 1985-2010 and analyze the status, motivation and positive and negative factors influencing research motivation of graduates in eight disciplines from three graduate schools of H
Autor:
Güldal Kirkali, Amanda K. McCullough, Vladimir Vartanian, Pawel Jaruga, Miral Dizdaroglu, R. Stephen Lloyd, Marcus J. Calkins, Nichole Owen
Oxidative stress and reactive oxygen species (ROS)-induced DNA base damage are thought to be central mediators of UV-induced carcinogenesis and skin aging. However, increased steady-state levels of ROS-induced DNA base damage have not been reported a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15cc554a2a707c0dc3b8dd714fb6322
https://europepmc.org/articles/PMC5499380/
https://europepmc.org/articles/PMC5499380/
Autor:
Hülya Ellidokuz, Zeynep Zadeoglulari, Safiye Aktaş, Nur Olgun, Güldal Kirkali, Zübeyde Erbayraktar
Publikováno v:
Turkish Journal of Biochemistry. 37:129-138
Objectives: The aim of the present study is to investigate the clinical significance of epigenetic changes in neuroblastoma, we evaluated the relationship between therapeutic variables and the pattern of gene methylation in neuroblastoma cell lines.
Autor:
Maria T. Ocampo-Hafalla, Miral Dizdaroglu, Karen L. Koenig, Michael K. Chan, R. Stephen Lloyd, Stuart M. Brown, George W. Teebor, Pawel Jaruga, Vladimir Vartanian, Güldal Kirkali
Publikováno v:
DNA Repair. 8:786-794
We have generated a strain of mice lacking two DNA N-glycosylases of base excision repair (BER), NTH1 and NEIL1, homologs of bacterial Nth (endonuclease three) and Nei (endonuclease eight). Although these enzymes remove several oxidized bases from DN
Autor:
Jocelyne DiRuggiero, C. Robinson, Pawel Jaruga, A. Kish, Miral Dizdaroglu, R. Rosenblatt, Güldal Kirkali
Publikováno v:
Environmental Microbiology
Environmental Microbiology, Society for Applied Microbiology and Wiley-Blackwell, 2009, 11 (5), pp.1066-1078. ⟨10.1111/j.1462-2920.2008.01828.x⟩
Environmental Microbiology, Society for Applied Microbiology and Wiley-Blackwell, 2009, 11 (5), pp.1066-1078. ⟨10.1111/j.1462-2920.2008.01828.x⟩
Summary The halophilic archaeon Halobacterium salinarum NRC-1 was used as a model system to investigate cellular damage induced by exposure to high doses of ionizing radiation (IR). Oxidative damages are the main lesions from IR and result from free
Publikováno v:
Free Radical Biology and Medicine. 45:1601-1609
Formamidopyrimidines, 4,6-diamino-5-formamidopyrimidine (FapyAde) and 2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyGua), are among major lesions in DNA generated by hydroxyl radical attack, UV radiation, or photosensitization in vitro and in vivo