Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Gül Özhan"'
Publikováno v:
Journal of Health and Pollution, Vol 11, Iss 31, Pp 1-13 (2021)
Background. Perfluorooctanoic acid (PFOA) is used in different industrial and commercial products. Research shows the presence of PFOA in home dusts, tap and surface water, and in biological samples. The International Agency for Research on Cancer (I
Externí odkaz:
https://doaj.org/article/e4f129305a2d4600be762936db4634c1
Publikováno v:
Global Medical Genetics, Vol 07, Iss 02, Pp 041-046 (2020)
Paraoxonase 1 (PON1) enzyme plays a major role in antioxidant defense and protects the cells against reactive species. The most common PON1 Q192R and L55M polymorphisms are responsible for a wide variation of PON1 activity, which showed an up to 13-f
Externí odkaz:
https://doaj.org/article/bf9443e91b734727a48cbfcc35b2c6b7
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 10, Iss 2, Pp 213-220 (2020)
Purpose: The wide application of cupric oxide nanoparticles (copper (II) oxide, CuO-NPs) in various fields has increased exposure to the kind of active nanomaterials, which can cause negative effects on human and environment health. Although CuO-NPs
Externí odkaz:
https://doaj.org/article/47f607cff9d04dd48af9e19d0b755ad2
Publikováno v:
Saudi Pharmaceutical Journal, Vol 27, Iss 3, Pp 422-431 (2019)
Objectives: Type 2 diabetes (T2DM) is one of the most serious challenges of the 21th century with life-threatening complications and excessive health care costs. In diabetic patients, the main goal in T2DM treatment is the regulation of both blood gl
Externí odkaz:
https://doaj.org/article/ef52ad35457f4d549666f454896a9bdb
Autor:
Ezgi Öztaş, Alejandro Parejo Garcia-Saavedra, Fatih Yanar, Beyza Özçinar, Nihat Aksakal, Sevim Purisa, Gül Özhan
Publikováno v:
Saudi Pharmaceutical Journal, Vol 26, Iss 2, Pp 274-278 (2018)
Objectives: P-glycoprotein (P-gp) contributes to the disposition of a wide variety of drugs; therefore, single nucleotide polymorphisms (SNPs) in the P-gp coding gene might affect its activity. It is well known that personalized medicine, instead of
Externí odkaz:
https://doaj.org/article/1503df93de6c40da832256d891fe257a
Autor:
Ezgi Öztaş, Mehtap Kara, Tuğçe Boran, Enes Bişirir, Ecem Fatma Karaman, Engin Kaptan, Gül Özhan
Publikováno v:
Biology, Vol 10, Iss 9, p 820 (2021)
Acetamiprid (ACE), a commonly used neonicotinoid insecticide, is correlated with neurological symptoms, immunotoxicity and hepatotoxicity. Cellular stress and damage could play an important role in ACE-induced neurotoxicity; however, its mechanism ha
Externí odkaz:
https://doaj.org/article/bc17268036074dfebdfc497095d4acdf
Autor:
Merve Arici, Gül Özhan
Publikováno v:
Saudi Pharmaceutical Journal, Vol 25, Iss 3, Pp 376-380 (2017)
Pharmacogenetics is a vast field covering drug discovery research, the genetic basis of pharmacokinetics and dynamics, genetic testing and clinical management in diseases. Pharmacogenetic approach usually focuses on variations of drug transporters, d
Externí odkaz:
https://doaj.org/article/d5e252c30c1540e0b82c5ae2b0371284
Autor:
Merve Arici, Gül Özhan
Publikováno v:
Saudi Pharmaceutical Journal, Vol 25, Iss 2, Pp 294-297 (2017)
Evaluation and sequencing of heritable alterations in the human genome and the large-scale identification of gene polymorphism for understanding the genetic background of individuals in response to potential toxicants are provided by toxicogenetics.
Externí odkaz:
https://doaj.org/article/baa00e6aea2b4909a883ef43477398d4
Publikováno v:
Mediators of Inflammation, Vol 2010 (2010)
Proinflammatory cytokines, such as tumour necrosis factor α (TNFα), play fundamental roles in the pathogenesis of acute pancreatitis (AP). The aim of this study was to determine if polymorphisms in the TNFα gene are associated with AP. Two polymor
Externí odkaz:
https://doaj.org/article/9a9ddac536ed495e8e0fcade347ca54d
Publikováno v:
Toxicology Mechanisms and Methods. 33:56-64