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The brain parenchyma has a type I interferon response that can limit virus spread.

Autor: Drokhlyansky E; Department of Genetics, Harvard Medical School, Boston, MA 02115.; Department of Ophthalmology, Harvard Medical School, Boston, MA 02115.; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115., Göz Aytürk D; Department of Genetics, Harvard Medical School, Boston, MA 02115.; Department of Ophthalmology, Harvard Medical School, Boston, MA 02115.; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115., Soh TK; Department of Microbiology and Immunobiology, Program in Virology, Harvard Medical School, Boston, MA 02115., Chrenek R; Department of Genetics, Harvard Medical School, Boston, MA 02115.; Department of Ophthalmology, Harvard Medical School, Boston, MA 02115.; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115., O'Loughlin E; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115., Madore C; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115., Butovsky O; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115., Cepko CL; Department of Genetics, Harvard Medical School, Boston, MA 02115; cepko@genetics.med.harvard.edu.; Department of Ophthalmology, Harvard Medical School, Boston, MA 02115.; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Jan 03; Vol. 114 (1), pp. E95-E104. Date of Electronic Publication: 2016 Dec 15.