Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Götz Pilarczyk"'
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 10, Pp 8152-8172 (2023)
The spatial organization of euchromatin (EC) and heterochromatin (HC) appears as a cell-type specific network, which seems to have an impact on gene regulation and cell fate. The spatial organization of cohesin should thus also be characteristic for
Externí odkaz:
https://doaj.org/article/d7ef0d980d3a4089a479fe68e6ad25c1
Autor:
Jonas Weidner, Charlotte Neitzel, Martin Gote, Jeanette Deck, Kim Küntzelmann, Götz Pilarczyk, Martin Falk, Michael Hausmann
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 2018-2034 (2023)
The cell as a system of many components, governed by the laws of physics and chemistry drives molecular functions having an impact on the spatial organization of these systems and vice versa. Since the relationship between structure and function is a
Externí odkaz:
https://doaj.org/article/e7d1bad348bb4894b790baf70549be24
Autor:
Jekaterina Erenpreisa, Alessandro Giuliani, Kenichi Yoshikawa, Martin Falk, Georg Hildenbrand, Kristine Salmina, Talivaldis Freivalds, Ninel Vainshelbaum, Jonas Weidner, Aaron Sievers, Götz Pilarczyk, Michael Hausmann
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2658 (2023)
Complex functioning of the genome in the cell nucleus is controlled at different levels: (a) the DNA base sequence containing all relevant inherited information; (b) epigenetic pathways consisting of protein interactions and feedback loops; (c) the g
Externí odkaz:
https://doaj.org/article/cd07d7715fc249c2a93e85880cb9b313
Autor:
Michael Hausmann, Charlotte Neitzel, Elizaveta Bobkova, David Nagel, Andreas Hofmann, Tatyana Chramko, Elena Smirnova, Olga Kopečná, Eva Pagáčová, Alla Boreyko, Evgeny Krasavin, Iva Falkova, Dieter W. Heermann, Götz Pilarczyk, Georg Hildenbrand, Felix Bestvater, Martin Falk
Publikováno v:
Frontiers in Physics, Vol 8 (2020)
High-LET (Linear Energy Transfer) particle irradiation as being provided from heavy ion accelerator facilities has an increasing impact on bio-medical research and cancer treatment. Nevertheless, there are a lot of open questions concerning the under
Externí odkaz:
https://doaj.org/article/f3b493e7cd2d4ba9a5b222fc9a1754f7
Autor:
Georg Hildenbrand, Philipp Metzler, Götz Pilarczyk, Vladimir Bobu, Wilhelm Kriz, Hiltraud Hosser, Jens Fleckenstein, Matthias Krufczik, Felix Bestvater, Frederik Wenz, Michael Hausmann
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190183 (2018)
Localization microscopy has shown to be capable of systematic investigations on the arrangement and counting of cellular uptake of gold nanoparticles (GNP) with nanometer resolution. In this article, we show that the application of specially modified
Externí odkaz:
https://doaj.org/article/d7627413ffd945108e322f3fa88279ec
Autor:
Michael Hausmann, Nataša Ilić, Götz Pilarczyk, Jin-Ho Lee, Abiramy Logeswaran, Aurora Paola Borroni, Matthias Krufczik, Franziska Theda, Nadine Waltrich, Felix Bestvater, Georg Hildenbrand, Christoph Cremer, Michael Blank
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 10, p 2066 (2017)
Understanding molecular interactions and regulatory mechanisms in tumor initiation, progression, and treatment response are key requirements towards advanced cancer diagnosis and novel treatment procedures in personalized medicine. Beyond decoding th
Externí odkaz:
https://doaj.org/article/7f38a55470204d21bb87d89872458e8c
Autor:
Götz Pilarczyk, Ines Nesnidal, Manuel Gunkel, Margund Bach, Felix Bestvater, Michael Hausmann
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 2, p 362 (2017)
In cancer, vulnerable breast epithelium malignance tendency correlates with number and activation of ErbB receptor tyrosine kinases. In the presented work, we observe ErbB receptors activated by irradiation-induced DNA injury or neuregulin- 1 β appl
Externí odkaz:
https://doaj.org/article/353fc61b7040492b97640364f71fc4cd
Autor:
Götz Pilarczyk, Alexandra Raulf, Manuel Gunkel, Bernd K. Fleischmann, Robert Lemor, Michael Hausmann
Publikováno v:
Journal of Functional Biomaterials, Vol 7, Iss 1, p 1 (2016)
The present work addresses the question of to what extent a geometrical support acts as a physiological determining template in the setup of artificial cardiac tissue. Surface patterns with alternating concave to convex transitions of cell size dimen
Externí odkaz:
https://doaj.org/article/5e7d5ea952d546d1b75eca7cc16343fd
Publikováno v:
Results and problems in cell differentiation. 70
The cell nucleus is a complex biological system in which simultaneous reactions and functions take place to keep the cell as an individualized, specialized system running well. The cell nucleus contains chromatin packed in various degrees of density
Networks and Islands of Genome Nano-architecture and Their Potential Relevance for Radiation Biology
Publikováno v:
Nuclear, Chromosomal, and Genomic Architecture in Biology and Medicine ISBN: 9783031065729
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1808ac9f0ebfa4c516061a139dd5cb29
https://doi.org/10.1007/978-3-031-06573-6_1
https://doi.org/10.1007/978-3-031-06573-6_1