Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Götz Munch"'
Autor:
Henry Nording, Lasse Baron, Antje Lübken, Hossein Emami, Jacob von Esebeck, Moritz Meusel, Christian Sadik, Nancy Schanze, Daniel Duerschmied, Jörg Köhl, Götz Münch, Harald F. Langer
Publikováno v:
TH Open, Vol 07, Iss 04, Pp e289-e293 (2023)
Externí odkaz:
https://doaj.org/article/627ff239267c4f828c468fa30e6d8a12
Autor:
Chao Han, Pengxuan Ren, Medina Mamtimin, Linus Kruk, Edita Sarukhanyan, Chenyu Li, Hans-Joachim Anders, Thomas Dandekar, Irena Krueger, Margitta Elvers, Silvia Goebel, Kristin Adler, Götz Münch, Thomas Gudermann, Attila Braun, Elmina Mammadova-Bach
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 423 (2023)
Glycoprotein VI (GPVI) is a platelet-specific receptor for collagen and fibrin, regulating important platelet functions such as platelet adhesion and thrombus growth. Although the blockade of GPVI function is widely recognized as a potent anti-thromb
Externí odkaz:
https://doaj.org/article/baa6ba13cc5e43369b4b0d501f8dc336
Autor:
Sara Alberti, Qianqian Zhang, Ilaria D’Agostino, Annalisa Bruno, Stefania Tacconelli, Annalisa Contursi, Simone Guarnieri, Melania Dovizio, Lorenza Falcone, Patrizia Ballerini, Götz Münch, Ying Yu, Paola Patrignani
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Neointima hyperplasia is a crucial component of restenosis after coronary angioplasty. We have hypothesized that enhanced generation of platelet-derived thromboxane (TX)A2 in response to vascular damage plays a critical role in neointimal hy
Externí odkaz:
https://doaj.org/article/e6a515e9c8494e3e985c043ce7cad9e0
Autor:
Stephan Zeibig, Manuela Büttcher, Silvia Goebel, Jessica Pauli, Annique Hunger, Martin Ungerer, Meinrad Gawaz, Götz Münch
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 4, Pp 681-695 (2019)
Externí odkaz:
https://doaj.org/article/4c41514e2a604d84a1f6134a46ccf8c2
Autor:
Klaus Gröschel, Timo Uphaus, Ian Loftus, Holger Poppert, Hans Christoph Diener, Jenny Zobel, Götz Münch
Publikováno v:
TH Open, Vol 04, Iss 04, Pp e393-e399 (2020)
Patients with stroke or transient ischemic attacks (TIAs) and internal carotid artery stenosis harbor an increased risk of recurrent stroke especially within 2 weeks after the first event. In addition, the revascularization procedure itself (carotid
Externí odkaz:
https://doaj.org/article/50c52a6765674d1fad370c1e205e74ac
Autor:
Götz Munch, Rosport, Kai, Baumgartner, Christine, Zhongmin Li, Wagner, Silvia, Bültmann, Andreas, Ungerer, Martin
Publikováno v:
American Journal of Physiology: Heart & Circulatory Physiology; Aug2006, Vol. 291 Issue 2, pH488-H495, 8p, 5 Graphs
Autor:
Janina Jamasbi, RPh, Remco T.A. Megens, PhD, Mariaelvy Bianchini, MSc, Kerstin Uhland, PhD, Götz Münch, MD, Martin Ungerer, MD, Shachar Sherman, BSc, Alexander Faussner, PhD, Richard Brandl, MD, Christine John, MSc, Johannes Buchner, PhD, Christian Weber, MD, Reinhard Lorenz, MD, Natalie Elia, PhD, Wolfgang Siess, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 3, Pp 131-142 (2016)
To enhance the antithrombotic properties of recombinant glycoprotein VI fragment crystallizable (GPVI-Fc), the authors incubated GPVI-Fc with anti-human Fc antibodies to cross-link the Fc tails of GPVI-Fc. Cross-linking potentiated the inhibition of
Externí odkaz:
https://doaj.org/article/61bf0fc198ea4ad180b532af81574356
Autor:
Valérie Boivin-Jahns, Kerstin Uhland, Hans-Peter Holthoff, Niklas Beyersdorf, Vladimir Kocoski, Thomas Kerkau, Götz Münch, Martin J Lohse, Martin Ungerer, Roland Jahns
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201160 (2018)
RATIONALE:Despite advances in pharmacotherapy, heart failure still incurs significant morbidity and mortality. Stimulating antibodies directed against the secondextracellular loop of the human ß1-adrenergic receptor (anti-ß1EC2) cause myocyte damag
Externí odkaz:
https://doaj.org/article/d7cea84fe6d649979c26f8103e1de8d4
Autor:
Heidrun Degen, Oliver Borst, Melanie Ziegler, Ann‐Katrin Mojica Munoz, Janina Jamasbi, Britta Walker, Silvia Göbel, Julia Fassbender, Kristin Adler, Richard Brandl, Götz Münch, Reinhard Lorenz, Wolfgang Siess, Meinrad Gawaz, Martin Ungerer
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 8 (2017)
BackgroundGPVI (Glycoprotein VI) is the essential platelet collagen receptor in atherothrombosis. Dimeric GPVI‐Fc (Revacept) binds to GPVI binding sites on plaque collagen. As expected, it did not increase bleeding in clinical studies. GPVI‐Fc is
Externí odkaz:
https://doaj.org/article/8c41f738c98d45e59044b26e25dfec32
Autor:
Silvia Goebel, Zhongmin Li, Jasmin Vogelmann, Hans-Peter Holthoff, Heidrun Degen, Dirk M Hermann, Meinrad Gawaz, Martin Ungerer, Götz Münch
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e66960 (2013)
OBJECTIVES: We examined the effect of Revacept, an Fc fusion protein which is specifically linked to the extracellular domain of glycoprotein VI (GPVI), on thrombus formation after vessel wall injury and on experimental stroke in mice. BACKGROUND: Se
Externí odkaz:
https://doaj.org/article/937b3af4b40a4cc6996c43a0a8fe2f9b