Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Götz, Nowak"'
Autor:
Peter Florian, Götz Nowak, Uwe Gerlach, Ralf Pasternack, Christiane Pelzer, Martin Hils, Christian Büchold, Andreas Heil, Michael Sommer, Robert Jähnig
Publikováno v:
Journal of Thrombosis and Haemostasis
Background Factor XIII (FXIII) is the final enzyme of the coagulation cascade. While the other enzymatic coagulation factors are proteases, FXIII belongs to the transglutaminase family. FXIIIa covalently crosslinks the fibrin clot and represents a pr
Publikováno v:
Veterinary Microbiology. 162:360-368
Classical swine fever (CSF) is a multi-systemic disease that can be accompanied by severe haemorrhagic lesions. The underlying pathogenetic mechanisms are still far from being understood, though disseminated intravascular coagulation (DIC) was discus
Publikováno v:
Journal of the Mechanical Behavior of Biomedical Materials. 13:215-229
Based on two fields, namely the placement and the calcium concentration, a chemo-mechanically coupled three-dimensional model, describing the contractile behaviour of smooth muscles, is presented by means of a strain energy function. The strain energ
Autor:
Mercedes Lopez, Götz Nowak
Publikováno v:
Seminars in Thrombosis and Hemostasis. 34:103-107
A model of functional nephrectomy and hepatectomy in rats was used to compare the pharmacokinetic profile of the direct competitive thrombin inhibitor argatroban in rats with renal, hepatic, or hepatorenal failure and rats with normal hepatic and ren
Publikováno v:
Seminars in Thrombosis and Hemostasis. 34:081-086
The ecarin chromogenic assay (HaemoSys ECA; JenAffin GmbH, Jena, Germany) was developed for quantitative determination of direct thrombin inhibitors. As a further development of the ecarin clotting time (ECT), the ECA is based on the same principle o
Autor:
Karsten Schrör, Götz Nowak
Publikováno v:
Thrombosis and Haemostasis. 98:116-119
Hirudin – the long and stony way from an anticoagulant peptide in the saliva of medicinal leech to a recombinant drug and beyond - A historical piece
Autor:
Götz Nowak
Publikováno v:
Transfusion Medicine and Hemotherapy. 34:413-419
The story of success of aspirin has lasted for more than 100 years. Initially used as an analgetic with anti-inflammatory, antirheumatic as well as antipyretic effects, aspirin has been widely used
Publikováno v:
Hämostaseologie. 27:105-110
ZusammenfassungDas zentrale Gerinnungsenzym, die Serinproteinase Thrombin, kann über die Protease-aktivierten Rezeptoren 1 und 4 der Tumorzellen in deren Wachstum modulierend eingreifen. Das Thrombin ist im Tumormikroenvironment permanent verfügbar
Autor:
Peter Nörtersheuser, Hans-ulrich Esslinger, Kristina Ulbricht, Katrin Annett Pöschel, Götz Nowak, Günter Stein, Elke Bucha
Publikováno v:
Kidney International. 65(2):666-674
Anticoagulant efficacy of PEG-Hirudin in patients on maintenance hemodialysis. Background Heparins are currently the anticoagulants of choice in long-term hemodialysis (HD). Because of their shortcomings, including the increasing incidence of heparin
Publikováno v:
Hämostaseologie. 24:211-216
ZusammenfassungDer Platelet ADhesion Assay (PADA) ist eine POCT-fähige Methode zur quantitativen Bestimmung der Plättchenadhäsivität. Durch spezielle Polymerpartikel und Testbedingungen, die den physiologischen Verhältnissen im Organismus angepa