Výsledky vyhledávání - "Gösta, Fischer"

A Novel C-Terminal Mutation in Gsdma3 (C+/H-) Leads to Alopecia and Corneal Inflammatory Response in Mice

Autor: Sebastian, Swirski, Carsten, Röger, Aldona, Pienkowska-Schelling, Cynthia, Ihlenburg, Gösta, Fischer, Oliver, May, Mariann, Vorm, Marta, Owczarek-Lipska, John, Neidhardt

Publikováno v: Investigative ophthalmologyvisual science. 59(1)

Mutations in the gene encoding Gasdermin A3 (Gsdma3) have been described to cause severe skin phenotypes, including loss of sebaceous glands and alopecia, in mice. We discovered a novel C-terminal mutation in Gsdma3 in a new mouse line and characteri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5f0a945828793267c5bf41b2d48915cd
https://pubmed.ncbi.nlm.nih.gov/29372254

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Relation between human papillomavirus positivity and p16 expression in head and neck carcinomas--a tissue microarray study

Autor: Frank, König, Gisbert, Krekeler, Johannes F, Hönig, Carlos, Cordon-Cardo, Gösta, Fischer, Monika, Korabiowska

Publikováno v: Anticancer research. 27(1A)

Overexpression of p16 has been demonstrated to be strongly related to the presence of HPV16, 18. Squamous cell carcinoma of the head and neck has been shown to be associated with human papillomavirus (HPV) infection. The main aim of this study was to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::60ed7f17b32c179df913cccf4a6cd6ad
https://pubmed.ncbi.nlm.nih.gov/17352245

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Alterations of the retinoblastoma and p16 pathway correlate with promoter methylation in malignant fibrous histiocytomas

Autor: Ulrich, Brinck, Thilo, Schlott, Steffi, Störber, Jerzy, Stachura, Pawel, Bortkiewicz, Wolf-Dieter, Nagel, Frank Michael, Hasse, Carlos, Cordon-Cardo, Gösta, Fischer, Monika, Korabiowska

Publikováno v: Anticancer research. 26(5A)

Recent reports indicate that the alterations in the p16 and pRb pathways can influence tumour progression and poor prognosis in several tumours. The objective of this study was to analyse p16 and pRb expression in161 patients with malignant fibrous h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::343c84b2f60c16d8ef95155515310835
https://pubmed.ncbi.nlm.nih.gov/17094467

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Altered expression of DNA double-strand repair genes Ku70 and Ku80 in carcinomas of the oral cavity

Autor: Monika, Korabiowska, Jann, Voltmann, Johannes F, Hönig, Pawel, Bortkiewicz, Frank, König, Carlos, Cordon-Cardo, Frederike, Jenckel, Petra, Ambrosch, Gösta, Fischer

Publikováno v: Anticancer research. 26(3A)

The relevance of double-strand DNA repair genes has been demonstrated in several tumours. The main aim of this study was to analyse the expression of the heterodimers Ku70 and Ku80, building regulatory subunits of the DNA-dependent protein kinase in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6a8fd3d812d586ad93eae56bafcc2b26
https://pubmed.ncbi.nlm.nih.gov/16827151

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Exonic deletions of mismatch repair genes MLH1 and MSH2 correlate with prognosis and protein expression levels in malignant melanomas

Autor: Monika, Korabiowska, Ulrich, Brinck, Jerzy, Stachura, Jacek, Jawien, Frank Michael, Hasse, Carlos, Cordon-Cardos, Gösta, Fischer

Publikováno v: Anticancer research. 26(2A)

The mutations of MLH1 and MSH2 have been reported to be responsible for malignant transformation and tumour progression in several sporadic tumours. Eighty-six primary malignant melanomas with known follow-up were investigated. Point mutations of DNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5a2677d375d2d197a4f62cb031cb5328
https://pubmed.ncbi.nlm.nih.gov/16619529

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Proposal of a new grading system for malignant fibrous histiocytomas

Autor: Ulrich, Brinck, Carlos, Cordon-Cardo, Jerzy, Stachura, Pawel, Bortkiewicz, Gösta, Fischer, Monika, Korabiowska

Publikováno v: Anticancer research. 25(6B)

The proposed grading system for malignant fibrous histiocytomas (MFH) comprises 3 grades of malignancy. Analogous to other grading systems, the system includes the factors of mitotic rate and necrosis. In addition to these two factors, the concept of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::52d2a6686c8a92b728c1246a45b20a93
https://pubmed.ncbi.nlm.nih.gov/16309231

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Relationship of nm23 expression to proliferation and prognosis in malignant melanomas of the oral cavity

Autor: Monika, Korabiowska, Johannes F, Hönig, Jacek, Jawien, Jadwiga, Knapik, Jerzy, Stachura, Carlos, Cordon-Cardo, Gösta, Fischer

Publikováno v: In vivo (Athens, Greece). 19(6)

Twenty-nine cases of oral melanomas were investigated for nm23 and Ki67 antigen expression, as well as for the fraction of tumour cells in S-phase, using immunohistochemical techniques and DNA cytophotometry. Nm23 expression was significantly reduced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::20de22c9ac30a6c06784eb483b285506
https://pubmed.ncbi.nlm.nih.gov/16277028

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Cytokeratin expression correlates with aneuploidy in cytological specimens of melanoma metastases

Autor: Monika, Korabiowska, Ilka, Ruschenburg, Harald, Schulz, Anja, Steinacker, Pawel, Bortkiewicz, Michael, Sevenich, Ulrich, Brinck, Carlos, Cordon-Cardo, Gösta, Fischer

Publikováno v: Anticancer research. 25(4)

It has been postulated that the high malignancy of melanomas could be connected with an increased cytokeratin (CK) expression. In order to define the relationship between CK expression and genetic instability of melanoma metastases, ploidy-related pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c6ee562daef022d3b8be93210b0d039a
https://pubmed.ncbi.nlm.nih.gov/16080528

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Application of new ploidy-related parameters for the diagnosis of ovarian tumours

Autor: Monika, Korabiowska, Ulrich, Brinck, Jacek, Skubis, Burkhart, Sattler, Gösta, Fischer

Publikováno v: Anticancer research. 24(6)

Differential diagnostics of borderline ovarian tumours and ovarian carcinomas is generally based on morphological criteria, which are not always sufficient for final diagnosis. Therefore, we investigated the practical diagnostic application of the CA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::49a1ead9d8e1caa3dc2f4a7841a1d662
https://pubmed.ncbi.nlm.nih.gov/15736472

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Cytokeratin positivity in paraffin-embedded malignant melanomas: comparative study of KL1, A4 and Lu5 antibodies

Autor: Monika, Korabiowska, Gösta, Fischer, Anja, Steinacker, Jerzy, Stachura, Carlos, Cordon-Cardo, Ulrich, Brinck

Publikováno v: Anticancer research. 24(5B)

The unclear role of cytokeratin (CK) in the progression and diagnostics of malignant melanomas stimulated us to compare the reactivity of three antibodies directed to CK in 109 paraffin-embedded melanomas. By far the majority of melanomas did not exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::df30e66c216ec370ea3898a71a61e2d9
https://pubmed.ncbi.nlm.nih.gov/15510611

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