Výsledky vyhledávání - "Göring Harald H H"

Akademický článek

Association of differential gene expression with imatinib mesylate and omacetaxine mepesuccinate toxicity in lymphoblastoid cell lines

Autor: Kulkarni Hemant, Göring Harald H H, Diego Vincent, Cole Shelley, Walder Ken R, Collier Greg R, Blangero John, Carless Melanie A

Publikováno v: BMC Medical Genomics, Vol 5, Iss 1, p 37 (2012)

Abstract Background Imatinib mesylate is currently the drug of choice to treat chronic myeloid leukemia. However, patient resistance and cytotoxicity make secondary lines of treatment, such as omacetaxine mepesuccinate, a necessity. Given that drug c

Externí odkaz: https://doaj.org/article/6ea2826efcf6495889c70b906f61bd5e

Zobrazit plný text záznamu

A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies

Autor: Li, Zilin, Li, Xihao, Zhou, Hufeng, Gaynor, Sheila M., Selvaraj, Margaret Sunitha, Arapoglou, Theodore, Quick, Corbin, Liu, Yaowu, Chen, Han, Sun, Ryan, Dey, Rounak, Arnett, Donna K., Auer, Paul L., Bielak, Lawrence F., Bis, Joshua C., Blackwell, Thomas W., Blangero, John, Boerwinkle, Eric, Bowden, Donald W., Brody, Jennifer A., Cade, Brian E., Conomos, Matthew P., Correa, Adolfo, Cupples, L. Adrienne, Curran, Joanne E., de Vries, Paul S., Duggirala, Ravindranath, Franceschini, Nora, Freedman, Barry I., Göring, Harald H. H., Guo, Xiuqing, Kalyani, Rita R., Kooperberg, Charles, Kral, Brian G., Lange, Leslie A., Lin, Bridget M., Manichaikul, Ani, Manning, Alisa K., Martin, Lisa W., Mathias, Rasika A., Meigs, James B., Mitchell, Braxton D., Montasser, May E., Morrison, Alanna C., Naseri, Take, O’Connell, Jeffrey R., Palmer, Nicholette D., Peyser, Patricia A., Psaty, Bruce M., Raffield, Laura M., Redline, Susan, Reiner, Alexander P., Reupena, Muagututi‘a Sefuiva, Rice, Kenneth M., Rich, Stephen S., Smith, Jennifer A., Taylor, Kent D., Taub, Margaret A., Vasan, Ramachandran S., Weeks, Daniel E., Wilson, James G., Yanek, Lisa R., Zhao, Wei, Rotter, Jerome I., Willer, Cristen J., Natarajan, Pradeep, Peloso, Gina M., Lin, Xihong

Publikováno v: Nat Methods

Large-scale whole-genome sequencing studies have enabled analysis of noncoding rare-variant (RV) associations with complex human diseases and traits. Variant-set analysis is a powerful approach to study RV association. However, existing methods have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c1582434c49b72b23e89d74944333d
https://doi.org/10.1038/s41592-022-01640-x

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání