Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Göran Selén"'
Autor:
Birgitta Ohman, Catrine E. Nilsson, Solveig Norling, Lars Abrahmsén, Gunnel Klingström, Cecilia Nilsson, Elisabet Bergqvist, Mandana Ashkzari, Eva Björkstrand, Naimie H. M. Edling, Maj Fiedler, Catarina Larsson, Lars O. M. Engblom, Göran Selén, Margareta Forsgren, Peteris Alberts
Publikováno v:
Endocrinology. 144:4755-4762
11 beta-Hydroxysteroid dehydrogenase type 1 (11 beta-HSD1) has been proposed as a new target for type 2 diabetes drugs. The aim of the present study was to assess the effects of inhibition of 11 beta-HSD1 on blood glucose levels, glucose tolerance, a
Publikováno v:
Pigment Cell Research. 13:147-150
Latanoprost, the active principle of Xalatan eye drops, is a prostaglandin F2alpha analogue in widespread use for the treatment of glaucoma. During chronic treatment with the drug, an increased pigmentation of the iris was observed in both primates a
Publikováno v:
Experimental Eye Research. 59:401-408
The effect of nitric oxide synthase inhibition on prostaglandin F2 alpha (PGF2 alpha)-induced ocular hyperemia in the rabbit has been studied. PGF2 alpha was administered topically as the isopropyl ester (PGF2 alpha-IE) unilaterally, with the other e
Publikováno v:
Sensors and Actuators A: Physical. 43:55-58
We have developed a passive pressure sensor intended primarily for intraocular pressure measurements. We have earlier reported the basic sensor and system design concepts, and initial experimental results. In this paper we present a method to improve
Publikováno v:
Journal of Cataract and Refractive Surgery. 18:247-251
In vivo long-term stability of intraocular lens surfaces, modified by immobilized heparin, was studied. Lenses were implanted in the anterior chamber of rabbits and analyzed for surface concentration of heparin after varying periods of time up to two
Autor:
Stephen James, Charlotte Söderberg Nyhem, Victor M. Castro, Eva Björkstrand, Catarina Larsson, Christina Kaiser, Göran Selén, Maj Sundbom
Publikováno v:
BMC Pharmacology
Background A substantial body of evidence indicates that reduced plasma adiponectin levels may be key in the development of insulin resistance, type 2 diabetes and the metabolic syndrome. Glucocorticoids decrease the levels of adiponectin in animals
Autor:
Anna-Lena Gustavsson, Jonas Uppenberg, Lena Jendeberg, Mona Sydow-Bäckman, Stefan Svensson, Markus Thor, Tove Östberg, Göran Selén, Maj Sundbom
Publikováno v:
The Journal of biological chemistry. 279(39)
The peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors belonging to the NR1 subfamily of nuclear receptors. The PPARs play key roles in the control of glucose and lipid homeostasis, and the synthetic isofor
Autor:
Kjell S. Sakariassen, Juleen R. Zierath, Harriet Wallberg-Henriksson, Göran Selén, Maj Fiedler, Yin Liang
Publikováno v:
Diabetologia. 44(12)
5-aminoimidazole-4-carboxy-amide-1-beta-d-ribofuranoside increases 5'-AMP-activated kinase activity in insulin-sensitive tissues known to control glucose homeostasis. We hypothesised that 5-aminoimidazole-4-carboxy-amide-1-beta-d-ribofuranoside treat
Publikováno v:
Progress in retinal and eye research. 19(4)
Prostaglandin F(2alpha) analogues have recently been introduced on the market for glaucoma treatment. While these drugs have a well-documented intraocular pressure reducing effect only a limited number of studies have been published regarding their e
Publikováno v:
Survey of ophthalmology. 41
Latanoprost, a new ocular hypotensive prostaglandin F2 alpha analogue prodrug, was found to induce increased pigmentation of monkey irides in chronic toxicity studies. This prompted us to investigate the effect of naturally occurring prostaglandins o