Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Göran, Hagman"'
Autor:
Makrina Daniilidou, Jasper Holleman, Göran Hagman, Ingemar Kåreholt, Malin Aspö, Ann Brinkmalm, Henrik Zetterberg, Kaj Blennow, Alina Solomon, Miia Kivipelto, Shireen Sindi, Anna Matton
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Cortisol dysregulation, neuroinflammation, and cerebrovascular dysfunction are biological processes that have been separately shown to be affected in Alzheimer’s disease (AD). Here, we aimed to identify biomarker signatures reflecting thes
Externí odkaz:
https://doaj.org/article/8c7751df030843d785cebe6217f0dcf6
Autor:
Charlotta Thunborg, Rui Wang, Anna Rosenberg, Shireen Sindi, Pia Andersen, Sandrine Andrieu, Laus M. Broersen, Nicola Coley, Celine Couderc, Celine Z. Duval, Gerd Faxen-Irving, Göran Hagman, Merja Hallikainen, Krister Håkansson, Eija Kekkonen, Jenni Lehtisalo, Nicholas Levak, Francesca Mangialasche, Johannes Pantel, Anders Rydström, Anna Stigsdotter-Neely, Anders Wimo, Tiia Ngandu, Hilkka Soininen, Tobias Hartmann, Alina Solomon, Miia Kivipelto
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) showed cognitive benefits from a multidomain lifestyle intervention in at-risk older people. The LipiDiDiet trial highlighted benefit
Externí odkaz:
https://doaj.org/article/989086a951054f3195f215b6ea45f7d8
Autor:
Jonas E. Svensson, Martin Bolin, Daniel Thor, Pete A. Williams, Rune Brautaset, Marcus Carlsson, Peder Sörensson, David Marlevi, Rubens Spin-Neto, Monika Probst, Göran Hagman, Anton Forsberg Morén, Miia Kivipelto, Pontus Plavén-Sigray
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Rapamycin is an inhibitor of the mechanistic target of rapamycin (mTOR) protein kinase, and preclinical data demonstrate that it is a promising candidate for a general gero- and neuroprotective treatment in humans. Results from mo
Externí odkaz:
https://doaj.org/article/6432726833fc4d12a5cd09fe328089f3
Autor:
Sára Mravinacová, Vilma Alanko, Sofia Bergström, Claire Bridel, Yolande Pijnenburg, Göran Hagman, Miia Kivipelto, Charlotte Teunissen, Peter Nilsson, Anna Matton, Anna Månberg
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background Amyloid and tau aggregates are considered to cause neurodegeneration and consequently cognitive decline in individuals with Alzheimer’s disease (AD). Here, we explore the potential of cerebrospinal fluid (CSF) proteins to reflec
Externí odkaz:
https://doaj.org/article/510df6556edb428db18f5039ba357301
Autor:
Dickson O. Adedeji, Jasper Holleman, Robert-Paul Juster, Chinedu T. Udeh-Momoh, Ingemar Kåreholt, Göran Hagman, Malin Aspö, Sofia Adagunodo, Krister Håkansson, Miia Kivipelto, Alina Solomon, Shireen Sindi
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 28, Iss , Pp 100592- (2023)
Background: Allostatic load (AL) is defined as the cumulative dysregulation of neuroendocrine, immunological, metabolic, and cardiovascular systems that increases the susceptibility to stress-related health problems. Several dementia and Alzheimer's
Externí odkaz:
https://doaj.org/article/2fafe853722843eeb3081733d6485019
Autor:
Alina Solomon, Miia Kivipelto, Ingemar Kåreholt, Chinedu T Udeh-Momoh, Jasper Holleman, Sofia Adagunodo, Göran Hagman, Malin Aspö, Shireen Sindi
Publikováno v:
BMJ Neurology Open, Vol 4, Iss 2 (2022)
Objective This study aims to investigate the relationship between diurnal cortisol patterns, cognition and Alzheimer’s disease (AD) biomarkers in memory clinic patients.Method Memory clinic patients were recruited from Karolinska University Hospita
Externí odkaz:
https://doaj.org/article/81075a73adcf4b1f9e0881e837b20306
Publikováno v:
Journal of Rehabilitation Medicine, Vol 53, Iss 9, p jrm00225 (2021)
Background and objective: Individuals with spina bifida often have cognitive impairments leading to dif-ficulties in education and daily activities. The aims of this study were to explore cognitive impairments in adults with spina bifida and to consi
Externí odkaz:
https://doaj.org/article/71de31a533f04a4f9b2afe347c19534a
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2019)
Abstract Background Determination of β-amyloid (Aβ) positivity and likelihood of underlying Alzheimer’s disease (AD) relies on dichotomous biomarker cut-off values. Individuals with mild cognitive impairment (MCI) and Aβ within the normal range
Externí odkaz:
https://doaj.org/article/6ea9f59acff04137b8b162b4c342a2c9
Autor:
Patrik Jonell, Birger Moëll, Krister Håkansson, Gustav Eje Henter, Taras Kucherenko, Olga Mikheeva, Göran Hagman, Jasper Holleman, Miia Kivipelto, Hedvig Kjellström, Joakim Gustafson, Jonas Beskow
Publikováno v:
Frontiers in Computer Science, Vol 3 (2021)
Non-invasive automatic screening for Alzheimer’s disease has the potential to improve diagnostic accuracy while lowering healthcare costs. Previous research has shown that patterns in speech, language, gaze, and drawing can help detect early signs
Externí odkaz:
https://doaj.org/article/0833e68562ee4a96a451e97c15df2cdc
Autor:
Martina Bendt, Hanna Gabrielsson, Dorothee Riedel, Göran Hagman, Claes Hultling, Erika Franzén, Mats Eriksson, Åke Seiger
Publikováno v:
Brain and Behavior, Vol 10, Iss 8, Pp n/a-n/a (2020)
Abstract Objective To describe health issues and living conditions in a cohort of adults living with Spina bifida. Material and methods A cross‐sectional study was conducted by a multidisciplinary team. Adults with spina bifida (n = 219) were invit
Externí odkaz:
https://doaj.org/article/a58059aa31164098b8edd0f8794b9e58