Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Gönül Hiçsönmez"'
Autor:
Gönül Hiçsönmez
Publikováno v:
Turkish Journal of Hematology, Vol 27, Iss 01, Pp 1-7 (2010)
Differentiation-inducing therapy with all-trans retinoic acid significantly improved the outcome in children with acute promyelocytic leukemia (APL). Therefore, use of agents that induce differentiation of leukemic cells in non-APL children appears t
Externí odkaz:
https://doaj.org/article/76dccd4f2ac740b6bd6e559efa99776c
Autor:
Gönül Hiçsönmez
Publikováno v:
International Journal of Stem cell Research & Therapy. 3
Autor:
Fatma Gumruk, Aytemiz Gurgey, Nilufer Karadeniz, Gülyüz Ertürk, Sinasi Özsoylu, A. Murat Tuncer, V. Prozorova Zamani, Gönül Hiçsönmez
Publikováno v:
European Journal of Haematology. 48:215-220
Since the differentiating effect of high-dose methylprednisolone (HDMP) on myeloid leukemic cells has been shown in one of our patients with acute myeloblastic leukemia (AML-M4), 27 previously untreated children with AML were given HDMP (20-30 mg/kg
Autor:
Aytemiz Gurgey, Charlotte M. Niemeyer, Gönül Hiçsönmez, Karl Seeger, Robin van Bruggen, Dirk Roos, Anton T.J. Tool, Nanne Kamerbeek, Taco W. Kuijpers, Arthur J. Verhoeven, A Karow, Ozden Sanal
Publikováno v:
Blood, 109(8), 3529-3537. American Society of Hematology
The syndrome of leukocyte adhesion deficiency (LAD) combined with a severe Glanzmann-type bleeding disorder has been recognized as a separate disease entity. The variability in clinical and cell biological terms has remained largely unclear. We prese
Autor:
Gönül Hiçsönmez
Publikováno v:
Leukemia Research. 30:60-68
Several in vitro studies have shown that dexamethasone (Dex) and prednisolone can induce differentiation of some mouse and human myeloid leukemic cells to macrophages and granulocytes. Based on in vitro experiments, we have shown that short-course (3
Long-term survival in severe combined immune deficiency: The role of persistent maternal engraftment
Autor:
Fügen Ersoy, Francois Le Deist, Tuba Turul, Geneviève de Saint Basile, S. Caillat-Zucmann, Ozden Sanal, Ilhan Tezcan, Duygu Uckan, Sevim Balci, Marguerite Prieur, Gönül Hiçsönmez
Publikováno v:
The Journal of Pediatrics. 146:137-140
Two siblings with severe combined immune deficiency, one with maternal engraftment and detectable immunologic functions who was alive at the age of 8 years are presented. Both patients had the same JAK3 gene mutation, suggesting that maternal engraft
Publikováno v:
American Journal of Hematology. 80:1-5
In our previous studies, short-course high-dose methylprednisolone (HDMP) has been shown to shorten the chemotherapy-induced neutropenic period by stimulating the CD34(+) hematopoietic progenitor cells in children with acute leukemia. In this study,
Autor:
Nazmiye Yüksek, Gunay Balta, Gönül Hiçsönmez, Emel Ozyurek, Aytemiz Gurgey, Cigdem Altay, Ulya Ertem
Publikováno v:
American Journal of Hematology. 73:154-160
The role of methylenetetrahydrofolate reductase (MTHFR C677T), glutathione S-transferases (GSTM1 and GSTT1 null, GSTP1 Ile105Val), and cytochromes p450 (CYP1A1*2A) genotypes in the etiology of childhood leukemia was simultaneously investigated. 144 T
Publikováno v:
Pediatric Hematology and Oncology. 20:373-379
The authors have previously demonstrated a favorable effect of high-dose methylprednisolone (HDMP), which can induce differentiation and apoptosis of leukemic cells in children with acute myeloblastic leukemia (AML). Here, they evaluate the effect of
Publikováno v:
Clinical & Laboratory Haematology. 23:33-37
The effect of single high-dose methylprednisolone (HDMP) on eosinophil and lymphocyte phenotype in two siblings with marked hypereosinophilia was investigated. Since conventional dose steroids failed to produce a haematological and clinical response