Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Gökhan, Karakülah"'
Autor:
Perihan Yagmur Guneri-Sozeri, Gülden Özden-Yılmaz, Asli Kisim, Ece Cakiroglu, Aleyna Eray, Hamdiye Uzuner, Gökhan Karakülah, Devrim Pesen-Okvur, Serif Senturk, Serap Erkek-Ozhan
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
The transcription factors FRA1 and FLI1 regulate cell migration and cell junction organization genes in muscle-invasive bladder cancer, and loss of these factors reduces cancer cell invasion, pointing toward a therapeutic avenue.
Externí odkaz:
https://doaj.org/article/e4c1a871085b4d33bd8ef8066b1d2292
Autor:
Sinem Gunalp, Derya Goksu Helvaci, Aysenur Oner, Ahmet Bursalı, Alessandra Conforte, Hüseyin Güner, Gökhan Karakülah, Eva Szegezdi, Duygu Sag
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundTNF-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can either induce cell death or activate survival pathways after binding to death receptors (DRs) DR4 or DR5. TRAIL is investigated as a therapeutic agent
Externí odkaz:
https://doaj.org/article/4de8f8e86e3642108304756b87a6437c
Autor:
Melih Özbek, Halil Ibrahim Toy, Yavuz Oktay, Gökhan Karakülah, Aslı Suner, Athanasia Pavlopoulou
Publikováno v:
PeerJ, Vol 11, p e15096 (2023)
Low-grade gliomas (LGG) are central nervous system Grade I tumors, and as they progress they are becoming one of the deadliest brain tumors. There is still great need for timely and accurate diagnosis and prognosis of LGG. Herein, we aimed to identif
Externí odkaz:
https://doaj.org/article/c7d9313953154cd8b42dcd7264135967
Publikováno v:
PeerJ, Vol 11, p e15099 (2023)
Keratins (KRTs) are the intermediate filament-forming proteins of epithelial cells, classified, according to their physicochemical properties, into “soft” and “hard” keratins. They have a key role in several aspects of cancer pathophysiology,
Externí odkaz:
https://doaj.org/article/a71d30a9a1564460948687a7f5d7d572
Autor:
Reza Arshinchi Bonab, Seyedehsadaf Asfa, Panagiota Kontou, Gökhan Karakülah, Athanasia Pavlopoulou
Publikováno v:
PeerJ, Vol 10, p e14149 (2022)
MicroRNAs represent major regulatory components of the disease epigenome and they constitute powerful biomarkers for the accurate diagnosis and prognosis of various diseases, including cancers. The advent of high-throughput technologies facilitated t
Externí odkaz:
https://doaj.org/article/9f634bba1b654661b6b9e82ea5302e14
Autor:
Gülden Özden-Yılmaz, Busra Savas, Ahmet Bursalı, Aleyna Eray, Alirıza Arıbaş, Serif Senturk, Ezgi Karaca, Gökhan Karakülah, Serap Erkek-Ozhan
Publikováno v:
Cells, Vol 12, Iss 6, p 836 (2023)
Epigenetic deregulation is a critical theme which needs further investigation in bladder cancer research. One of the most highly mutated genes in bladder cancer is KDM6A, which functions as an H3K27 demethylase and is one of the MLL3/4 complexes. To
Externí odkaz:
https://doaj.org/article/6f40010068f14d7099c558314aeb9bfc
Autor:
Meltem Kuruş, Soheil Akbari, Doğa Eskier, Ahmet Bursalı, Kemal Ergin, Esra Erdal, Gökhan Karakülah
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The generation and use of induced pluripotent stem cells (iPSCs) in order to obtain all differentiated adult cell morphologies without requiring embryonic stem cells is one of the most important discoveries in molecular biology. Among the uses of iPS
Externí odkaz:
https://doaj.org/article/67779599df244c4ba1ef762e5a5d8f22
Autor:
Melih Özbek, Halil Ibrahim Toy, Işil Takan, Seyedehsadaf Asfa, Reza Arshinchi Bonab, Gökhan Karakülah, Panagiota I. Kontou, Styliani A. Geronikolou, Athanasia Pavlopoulou
Publikováno v:
Viruses, Vol 15, Iss 1, p 104 (2022)
The COVID-19 pandemic has persisted for almost three years. However, the mechanisms linked to the SARS-CoV-2 effect on tissues and disease severity have not been fully elucidated. Since the onset of the pandemic, a plethora of high-throughput data re
Externí odkaz:
https://doaj.org/article/f9b63ca4e1fe44ec9469802909f80f3b
Autor:
Cihangir Yandım, Gökhan Karakülah
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-16 (2019)
Abstract Background The last decade witnessed a number of genome-wide studies on human pre-implantation, which mostly focused on genes and provided only limited information on repeats, excluding the satellites. Considering the fact that repeats const
Externí odkaz:
https://doaj.org/article/80e9530a53a7490089e9a32d92f9e574
Autor:
Halil Ibrahim Toy, Gökhan Karakülah, Panagiota I. Kontou, Hani Alotaibi, Alexandros G. Georgakilas, Athanasia Pavlopoulou
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Eradication of cancer cells through exposure to high doses of ionizing radiation (IR) is a widely used therapeutic strategy in the clinical setting. However, in many cases, cancer cells can develop remarkable resistance to radiation. Radioresistance
Externí odkaz:
https://doaj.org/article/566d512f234a4651951586002f786e5c